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1. Çocuklarda Kalp Yetmezliği Doç.Dr.Zülal Ülger

7. Çocuklarda Kalp Yetmezliği- Tele M iyokardit (a kut ) Dilate KMP(Kronik )

8. Çocuklarda Kalp Yetmezliği-EKO Restri k ti f KMP H i pertro fik KMP Dilate KMP –4 boşluk Dilate KMP – Uzun eksen axis

9. Endomiyokardiyal Biyopsinin Rolü Normal Restri ktif KMP EMB ile miyokardit dışlanabilir. Ayrıca depo hastalığı, sarkoidoz, amiloidoz ve dev hücreli miyokardit ayırıcı tanısında yardımcı . Dilate KMP M iyokardit

12. Kalp Yetmezliği- N örohormonal aks Epinephrine Norepinephrine Hypertrophy Increased O 2 Consumption Poor systolic function Decreased compliance Poor diastolic function Arrhythmogenicity Increased afterload Oxidative damage Platelet aggregation Myocardial ischemia NO secretion Prostacyclin Bradykinin ENDOTHELIUM Hyperplasia Collagen deposition Fibrosis FIBROBLASTS MYOCYTES Increased contractility Increased rate Increased wall stress Aldosterone • Sodium retention • Potassium depletion • Magnesium depletion • Catecholamine potentiation • Decrease arterial compliance • Cardiac remodeling Angiotensin II • Sodium retention • Increase vascular tone • Cardiac remodeling • Aldosterone release • Pro - inflammatory Renin Cardiac Dysfunction Decreased Cardiac Output Epinephrine Norepinephrine Hypertrophy Increased O 2 Consumption Poor systolic function Decreased compliance Poor diastolic function Arrhythmogenicity Increased afterload Oxidative damage Platelet aggregation Myocardial ischemia NO secretion Prostacyclin Bradykinin ENDOTHELIUM NO secretion Prostacyclin Bradykinin ENDOTHELIUM Hyperplasia Collagen deposition Fibrosis FIBROBLASTS Hyperplasia Collagen deposition Fibrosis FIBROBLASTS MYOCYTES Increased contractility Increased rate Increased wall stress MYOCYTES Increased contractility Increased rate Increased wall stress Aldosterone • Sodium retention • Potassium depletion • Magnesium depletion • Catecholamine potentiation • Decrease arterial compliance • Cardiac remodeling Angiotensin II • Sodium retention • Increase vascular tone • Cardiac remodeling • Aldosterone release • Pro - inflammatory Renin Renin Cardiac Dysfunction Decreased Cardiac Output

17. Berlin Heart Ventricular Assist Device