The document summarizes research into investigating the neuroprotective effects of the peptide PRARIY in models of spinal cord injury in vitro. The research aimed to characterize neuronal cell death induced by excitotoxic and inflammatory stimuli in cell culture models, study the uptake and localization of fluorescently-labelled PRARIY peptide in neurons, and determine if PRARIY provides neuroprotection compared to a scrambled control peptide. Preliminary results found PRARIY entered neurons and reduced cell death induced by glutamate, though results were inconclusive due to variability between experiments. Future work proposed improving the cell death model and further investigating PRARIY's effects and localization.