This document discusses advancements in time-delay estimation (TDE) and acoustic source localization using supervised neural networks, presenting results that outperform traditional methods such as cross-correlation and adaptive eigenvalue decomposition in challenging environments. The authors argue that classical TDE techniques fail to adequately address the complexities of real-world acoustic scenarios, and their neural network-based approach leverages large datasets to yield robust estimates. A comprehensive statistical analysis demonstrates that neural network estimators significantly reduce estimation error and variance compared to non-supervised techniques, particularly in the presence of noise.