This chapter introduces double multi-layer potential operators associated with elliptic, higher-order, homogeneous, constant coefficient differential operators. It first discusses the nature of fundamental solutions for such operators. It defines various types of ellipticity for a differential operator, including W-ellipticity, ellipticity satisfying the Legendre-Hadamard condition, and S-ellipticity. It also discusses properties like symmetry and self-adjointness of differential operators and their relationship to the coefficients.