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Combined Computerized Cognitive Remediation Treatment and Vocational Services for Schizophrenia   Morris Bell, Ph.D. Yale University Department of Psychiatry Schizophrenia Research Forum Webinar December 15, 2011
Mission Statement “ Exploring Ways to Restore Cognitive and Work Capacity” Learning Based Recovery Center
Predictors of work performance Substance use Symptoms Insight Cognition
Predictors of work performance improvement ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Bell & Bryson, 2001 Bryson & Bell, 2003
Neurocognition, social cognition, perceived social discomfort and vocational outcomes in schizophrenia.  Bell, Tsang, Greig & Bryson, Schizophrenia Bulletin, 2008
Neurocognitive Enhancement Therapy (NET) and Work Therapy (WT) Rehabilitation Research and Development, Department of Veterans Affairs
Active Intervention  Follow-up Time by condition p < .05 H O U R S W O R K E D
Hours Worked for NET Responders and Non-responders over Time Active Intervention  Follow-up P < .02
Work Status at 12 Month Follow-up ,[object Object],P = .12
NET and Supported Employment (SE) Funded by National Institute of Mental Health
Work Performance During Rehabilitation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Work Performance Composite Score at 12-months ,[object Object],[object Object],[object Object],[object Object]
Figure 4: Cumulative Rates of Employment Transitional + Competitive Quarters Weeks Competitive p < .05
Active Intervention Follow-up Quarters H O U R S Quarterly Work Hours (Transitional and Competitive) by Condition P<.05* P<.05* *  Significant group-by-time (p <.01) and linear trend (p < .01).  Same results using ranked data.
Active Intervention Follow-up Quarters H O U R S Quarterly  Competitive  Work Hours by Condition P<.05* *  Significant difference in linear trend for Quarters Q5-Q8 (p<.05).
Effect Size Differences at 2 yr FU between Cog Tx and No Cog Tx using Z scores adjusted for Baseline Functioning N = 92
Community Function at Intake and Competitive Employment over 2 years (N = 174)  (Bell MD, Corbera S, Wexler B. SIRS 2012) Rates of employment for Poor QLS differ significantly by condition p<.007 %

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Morris Bell Schiz res forum webinar

  • 1. Combined Computerized Cognitive Remediation Treatment and Vocational Services for Schizophrenia Morris Bell, Ph.D. Yale University Department of Psychiatry Schizophrenia Research Forum Webinar December 15, 2011
  • 2. Mission Statement “ Exploring Ways to Restore Cognitive and Work Capacity” Learning Based Recovery Center
  • 3. Predictors of work performance Substance use Symptoms Insight Cognition
  • 4.
  • 5. Neurocognition, social cognition, perceived social discomfort and vocational outcomes in schizophrenia. Bell, Tsang, Greig & Bryson, Schizophrenia Bulletin, 2008
  • 6. Neurocognitive Enhancement Therapy (NET) and Work Therapy (WT) Rehabilitation Research and Development, Department of Veterans Affairs
  • 7. Active Intervention Follow-up Time by condition p < .05 H O U R S W O R K E D
  • 8. Hours Worked for NET Responders and Non-responders over Time Active Intervention Follow-up P < .02
  • 9.
  • 10. NET and Supported Employment (SE) Funded by National Institute of Mental Health
  • 11.
  • 12.
  • 13. Figure 4: Cumulative Rates of Employment Transitional + Competitive Quarters Weeks Competitive p < .05
  • 14. Active Intervention Follow-up Quarters H O U R S Quarterly Work Hours (Transitional and Competitive) by Condition P<.05* P<.05* * Significant group-by-time (p <.01) and linear trend (p < .01). Same results using ranked data.
  • 15. Active Intervention Follow-up Quarters H O U R S Quarterly Competitive Work Hours by Condition P<.05* * Significant difference in linear trend for Quarters Q5-Q8 (p<.05).
  • 16. Effect Size Differences at 2 yr FU between Cog Tx and No Cog Tx using Z scores adjusted for Baseline Functioning N = 92
  • 17. Community Function at Intake and Competitive Employment over 2 years (N = 174) (Bell MD, Corbera S, Wexler B. SIRS 2012) Rates of employment for Poor QLS differ significantly by condition p<.007 %

Editor's Notes

  1. Our results and those of other labs indicate important relationships between cognition and vocational functioning Cognitive ability also relevant for many other interventions and outcomes This underscores the importance of searching for ways to remediate cognitive impairments in schizophrenia.