Mr. S, a 74-year-old male with diabetes, hypertension, heart disease, and kidney failure, presented to the emergency room with a fever of 38.6°C for one day and neck pain radiating to his head for five days. Examination was unremarkable. Blood cultures grew methicillin-sensitive Staphylococcus aureus sensitive to cefazolin. A CT scan and MRI of the neck showed abnormalities. The plan is to remove the permacath catheter, perform an echocardiogram, continue IV antibiotics, correct hyperkalemia, and follow up with spine surgery. The diagnosis is bacteremia likely from the intravascular catheter.
Weekly Case Presentation. Department of Medicine. EMCH.
Case: Tuberculous Pleural Effusion.
Our case this week (Nov. 5th, 2017) was 19 year old male presenting with fever, weight loss and cough for a prolonged duration. By means of proper history taking, physical evaluation and clinical investigation we have tried to adequately manage the case and it was presented before an audience comprising of clinical students to professors at our institute.
P.S. This presentation was made by interns of the institute. Hope any mistakes or faults will be met with constructive criticism as we look forward to improving ourselves.
Thank you.
Weekly Case Presentation. Department of Medicine. EMCH.
Case: Tuberculous Pleural Effusion.
Our case this week (Nov. 5th, 2017) was 19 year old male presenting with fever, weight loss and cough for a prolonged duration. By means of proper history taking, physical evaluation and clinical investigation we have tried to adequately manage the case and it was presented before an audience comprising of clinical students to professors at our institute.
P.S. This presentation was made by interns of the institute. Hope any mistakes or faults will be met with constructive criticism as we look forward to improving ourselves.
Thank you.
left ventricular hypertrophy, coarcatation of the aorta. contains case discussion, diagnosis, management, discussion, pathophysiology, treatment and labs.
Breast Cancer SOAP noteName Sharon BroomDate JanuarCicelyBourqueju
Breast Cancer SOAP note
Name Sharon Broom
Date: January/17/2020.
Age: 45 years old
Gender: Female
Time:12:45
SUBJECTIVE:
Chief Complaint:
“I have a sore lump on the left breast."
History of Present Illness:
Sharon is a 45-year-old female with complaints of a painful lump on her left breast for a month. The patient indicates that she feels unbalanced lumps on her left breast that are painful on the outer and upper corners. The patient observed the areas of the left outer breast worsening in terms of size and pain in the past week. She has experienced the pain of level four out of ten. Her mother was detected to have breast cancer prior to the age of 50. She has had a history of hysterectomy because of irregular periods, menorrhagia. The patient refutes swelling, increased warmth, and redness of the left breast. She repudiates nipple discharge swollen glands, chills, and fever.
History
Past Medical History:
Fibrocystic breast disease, Vitamin D deficiency, Urinary tract infection, Hypothyroidism, Hypocalcemia, and Constipation
Screenings:
Blood Pressure screening (2016 N/A)
Dental Examination (2016 N/A)
Eye Examination (2016 N/A)
Mammogram (2016 BiRad 2)
Pap smear- normal
HPV test- normal
GTPAL: G=1.T=0. P=0. A=0. L=1 (Normal vaginal delivery without complication)
Menstrual Hx: started at the age of 14. Normal PAP outcomes. LMP (cannot recall)-hysterectomy (07.2012)
Post Hospitalizations: Admitted to hospital for hysterectomy for one week
Past Surgical History: Hysterectomy (07. 2012)
Medications:
Armour Thyroid 30mg oral tablet: consume two pills on Monday, Wednesday, and Friday and three pills other days.
Therapy: 15 May 2015
Last Rx: 5 April 2016
Allergies:
Food allergies, Penicillin Triple Sulfa Vaginal CREA
Family History:
The patient’s mother passed away at the age of fifty, with a medical history of breast cancer. Sharon’s father is still alive at the age of seventy, with a medical record of hypertension. The patient has a younger brother aged 35 years and has no medical glitches. The patient has a sixteen-year-old son, who is healthy.
Social History:
The patient is divorced, and she lives with her son. She does not smoke but consumes alcohol irregularly. Sharon takes a regular diet that has no restrictions. She has no worries about weight loss or gains since she exercises two to three times weekly. The patient continually puts on a seatbelt when driving, wears sunscreen.
Sexual/Contraceptive History:
She has not been sexually active for at least a year, but previously, she had a monogamous relation. Birth control: Utilized condoms before. The patient has no fears with sexual performance or feelings.
...
A case of 42 year old male presented with fever, weight loss and axillary swelling and shortness of breath. so what will be diagnosis and further management?
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
2. Chief Complain
• Mr.S is a 74 years old presented to ER complaining
of Documented Spiking of 38.6 and Neck pain
3. History of Presenting Illness
• Mr.S is a 74 years old male KCO DM , HTN , IHD (PCI to LAD 2010 ) and recent
diagnosis of Unstable Angina , and ESRD on PermaCath since last 6 months
• He presented to our ER complaining of Documented spiking fever of 38.6
(highest) that started 1 day ago and , no diurnal variation , not associated with
weight loss or night sweats and Neck pain that is constant but radiates to the upper
shoulders and back of his head as a shock wave , started 5 days ago with no change
in course , no exacerbating or aggravating factors , pain is sever effecting pt sleep
• No Photophobia , no phonophobia , lasted more then 72 hours , never had
similar episodes , no lacrimation or rhinorea
• No Seasonal variation , doesn’t change with position , doesn’t have a stressful or
tense life , No Rash , no Hx of recent Travel outside Saudi Arabia
4. • Past Medical and surgical :
– Kco DM , HTN , IHD and ESRD
– Hernia Repair 30 years ago , and Cardiac Catheterization with PCI 10 years ago
– No Hx of blood Transfusion or Allergy
– He is using Aspirin , Clopidogrel , Bisoprolol , Isosorbide Dinitrate , Hydralazine , Amlodipine ,
Insulin NPH , and Sodium Bicarbonate
• Family Hx :
– His Mother was diagnosed with HTN
– His Father was diagnosed with DM
– No Family Hx of similar Episodes in the family
• Social Hx :
– he lives in Al-Biasha
– He is a retired
– He doesn’t smoke , and doesn’t exercise requlerly
5. Review of Systems
• Respiratory :
– No chough , no SOB , no hemoptysis
• Gastrointestinal :
– No abdominal pain , no dysphagia , no diarrhea
• Genitourinary :
– No dysuria , no flank pain , No Hesitancy
• Neurological :
– No weakness , no dizziness , Neck pain with radiation to upper shoulder and scalp
• Musculoskeletal :
– No joint pain , no muscle pain , no history of Trauma
• Hematology :
– No Bruising , no history of ease of bleeding, no history of Autoimmune disease
• Endocrine :
– No history of cold intolerance or Polyuria
6. General Examination :
Patient was Lying comfirtabilly on bed , with Peripheral IV line and PermaCath on the right
side , he looks in mild pain with acceptable body weight
Hand Examination :
-there was no rashes , ulcers , or discolorations
-No jenway lesions or Splinter Hemorrhage
-no joint pain , redness , tenderness , swelling , or change in temperature
-no limitation in range of motion
Head and Neck :
-no Malar rash , no Jaundice , no hair loss , no evidence of Annuler stomatitis , no Cyanosis
- JVP wasn’t raised
- No Generalized Lymphadenopathy
- Limited movement of the neck to the right side due to pain
7. CardioVasculer Exam
• Reguler pulse with rate of 78
• Inspection : no visible prominent veins , no visible pulsation , no
Scars , No discoloration , JVP wasn’t raised
• Palpation : no palpable thrills or Parasternal heaves , PMI was in
midclavicular line 5th intercostal space , No tenderness
• Auscultation : First and Second Heart sounds are audiable in all
auscultatory areas with no added sounds , no Murmurs
• No Basal Crackles , No lower limbs edema , no splenomegaly
• PermaCath looks clean , no redness surrounding it , no pus or
discharge
8. Respirstory Examination
• Inspection :
– Chest movement was symmetrical , RR : 18
• Palpation :
– Trachea was central ,equal chest expansion , no Subcutaneous
emphysema
– No palpable lymph nodes (anterior and posterior triangle ,
Supraclavicular , and axillary region)
• Percussion :
– Bilateral Resonant all over chest
• Auscultation :
– Vesicular Breathing equal bilaterally all over chest
– No Wheezing or crackles
9. Gastrointestinal Examination
• Inspection :
– Normal Abdominal Contour , symmetrical , Umbilicus is inverted
– No visible hernia , no visible dilated veins , no visible masses
• Palpation :
– Soft and lax , no tenderness , no palpable masses
– No Hepatomegaly or Splenomegaly
• Percussion :
– No shifting dullness
– Liver span is approximately 10 cm
• Auscultation :
– Audible bowel sounds , no renal bruit
10. Musculoskeletal Examination
• Joints :
– No visible joint or bone deformities
– No tenderness on movement or palpation , no swelling
, no difference in temperature
– No decreased ROM , swelling or erythema
• Muscle :
• No Proximal or Distal Weakness , no Tenderness
11. Neurological Examination
• GCS : 15/15
• Upper limbs :
– Sensory : intact for touch and pain
– Normal power , tone and reflexes
• Lower Limbs :
– Sensory : intact to touch and pian
– Normal power , tone and reflexes
• Limited movement of the neck to the right side due to pain
• Negative Brudzinksi and Kernigy’s sign
12. Summary
• Mr.S is a 74 years old male kco DM , HTN , IHD ,
and ESRD presented to ER complaining of Spiking
fever of 38.6 last 1 day and Hx of Neck pain with
radiation to scalp and upper shoulder since 5 days
• Examination was unremarkable
19. Plan :
• To Remove PermiCatheter (source of infection)
• Echo to rule Infective Endocarditis
• Repeat Blood Culture until negative
• Follow up with Spine Surgery
• IV ABX Cefazolin to be continued for 14 days from
last negative Blood culture
• Correct Hyperkalemia
20. Bactremia
• Primary Infection : due to direct inoculation of the blood ,
in pts on Intravasculer Catheter
• Secondary Infection : due to infection in another site
spreading to blood stream like due to UTI
• Common organisms : S.Aureus , Beta hemolytic strep ,
Enterococci , GNR
• Time To grow :
– High risk : <24 hours
– Low risk : >72 h unless slow growing organisms HACEK
21. Diagnosis
• Obtain Blood culture prior to abx if possible >2
sets (2 bottles in each set , each with 10 cc blood)
• If proven bactremia then daily surveillance cxs
until negative for 48 hours
• If S.Aureus obtain TEE or TTE