This document outlines a proposed structure and initial results from modelling the global macroeconomic impacts of decarbonizing the energy system using an integrated energy-economy model called ETSAP-TIAM-MSA. The model links the bottom-up energy system model ETSAP-TIAM with a macroeconomic model called MSA. Initial results show that meeting climate targets leads to lower carbon emissions but can reduce GDP by up to 5% in some regions by 2050 compared to baseline scenarios without climate policy. The model captures non-linear demand responses to energy costs that cannot be represented by simple demand elasticities. Further work is needed to refine regional calibrations and test sensitivities.