Versatile and experienced chemist with seven years of expertise in research and development. Proficient in gas chromatography, mass spectrometry, HPLC, UVFNIL, ICPFAES, and wastewater analysis. Collaborative leader with demonstrated history of providing solutions to challenging problems facing industry managers and organizational teams. Bilingual in French and English.
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
TIE microplastics immersed in Muskegon Lake, Michiganjeanniekane
Toxicity analysis of three different types of microplastics - polyethylene, polypropylene, and polystyrene - immersed in the benthic and pelagic regions of Muskegon Lake, Michigan
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
TIE microplastics immersed in Muskegon Lake, Michiganjeanniekane
Toxicity analysis of three different types of microplastics - polyethylene, polypropylene, and polystyrene - immersed in the benthic and pelagic regions of Muskegon Lake, Michigan
Is Marcellus Shale Frack Wastewater More Radioactive Than Previously Thought?Marcellus Drilling News
A study by the University of Iowa researchers, titled "Understanding the Radioactive Ingrowth and Decay of Naturally Occurring Radioactive Materials in the Environment: An Analysis of Produced Fluids from the Marcellus Shale" and published in the peer reviewed journal Environmental Health Perspectives in April 2015. The research reportedly shows a new method for testing the total potential radioactivity of shale wastewater not previously considered. The chief shortcoming of the research is that it is based on a single sample from a single Marcellus Shale well.
A review on nickel(II) adsorption in single and binary component systems and ...Dr. Md. Aminul Islam
Waterpollutedwithheavy-metalionhasbeenamajorprobleminrecentyears.Amongvariousmetalions,nickel (II) is a priority pollutant commonly found in industrial wastewater. As a highly toxic element at an elevated concentration, Ni(II) can pose a serious threat to our ecological environment as well as human being. Ni(II) adsorption from wastewater is a must for environmental management and sustainability. Remediation of Ni(II) contaminated water is possible through adsorption onto various innovative adsorbents from the aquatic environment. The current review looks at the present status of the research done so far Ni(II) adsorption using various adsorbents from wastewater. Ni(II) adsorption kinetics, edges, isotherm, thermodynamic parameters, and Ni(II) adsorption mechanism have also been talked over. Efforts have also been made to steer out of the advantages and disadvantages of adsorbents and the future research need in Ni(II) adsorption by adsorbents. Agricultural based substrates and nanosized metal oxides have been found a hopeful alternative for Ni(II) adsorption from wastewater. The Ni(II) primarily adsorbed ontoa homogeneous substrate forming a monolayer. Ni (II) generally formed outer-sphere complexes at low pH values while it formed inner-sphere complexes at higher pH. More than one species is being sorbed, or more than one type of surface site is involved in Ni(II) adsorption process or both. However, significant research is needed to understand Ni(II)-surface interaction mechanism at the solid-water interface. This review can fill the lacuna of researchers who would like to do more research in this related area in depth.
I am a graduate from Saint Michael's College with over a year's experience in the Biotech industry. I am interested in any opportunity to grow in the scientific field.
Is Marcellus Shale Frack Wastewater More Radioactive Than Previously Thought?Marcellus Drilling News
A study by the University of Iowa researchers, titled "Understanding the Radioactive Ingrowth and Decay of Naturally Occurring Radioactive Materials in the Environment: An Analysis of Produced Fluids from the Marcellus Shale" and published in the peer reviewed journal Environmental Health Perspectives in April 2015. The research reportedly shows a new method for testing the total potential radioactivity of shale wastewater not previously considered. The chief shortcoming of the research is that it is based on a single sample from a single Marcellus Shale well.
A review on nickel(II) adsorption in single and binary component systems and ...Dr. Md. Aminul Islam
Waterpollutedwithheavy-metalionhasbeenamajorprobleminrecentyears.Amongvariousmetalions,nickel (II) is a priority pollutant commonly found in industrial wastewater. As a highly toxic element at an elevated concentration, Ni(II) can pose a serious threat to our ecological environment as well as human being. Ni(II) adsorption from wastewater is a must for environmental management and sustainability. Remediation of Ni(II) contaminated water is possible through adsorption onto various innovative adsorbents from the aquatic environment. The current review looks at the present status of the research done so far Ni(II) adsorption using various adsorbents from wastewater. Ni(II) adsorption kinetics, edges, isotherm, thermodynamic parameters, and Ni(II) adsorption mechanism have also been talked over. Efforts have also been made to steer out of the advantages and disadvantages of adsorbents and the future research need in Ni(II) adsorption by adsorbents. Agricultural based substrates and nanosized metal oxides have been found a hopeful alternative for Ni(II) adsorption from wastewater. The Ni(II) primarily adsorbed ontoa homogeneous substrate forming a monolayer. Ni (II) generally formed outer-sphere complexes at low pH values while it formed inner-sphere complexes at higher pH. More than one species is being sorbed, or more than one type of surface site is involved in Ni(II) adsorption process or both. However, significant research is needed to understand Ni(II)-surface interaction mechanism at the solid-water interface. This review can fill the lacuna of researchers who would like to do more research in this related area in depth.
I am a graduate from Saint Michael's College with over a year's experience in the Biotech industry. I am interested in any opportunity to grow in the scientific field.
I am a second year Doctor of Pharmacy student at the University of Michigan, Ann Arbor. I am currently seeking out a summer internship in the healthcare field and I am providing you with my resume in hopes I may fulfill needs of a position between the months of May and August. I have a strong interest in the pharmaceutical industry as well as clinical trials and drug design. However, my mind is open to anything!
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
1. MICHAEL D. VINCENT
Phone: 337.849.8349
Email: mdv4838@yahoo.com
PRO F E S S IO N AL CHE M IS T
Versatile and experienced chemist with seven years of expertise in research and development. Proficient in gas
chromatography, mass spectrometry, HPLC, UVFNIL, ICPFAES, and wastewater analysis. Collaborative leader with
demonstrated history of providing solutions to challenging problems facing industry managers and organizational
teams. Bilingual in French and English.
PROFESSIONAL EXPERIENCE
LEAD CHEMIST- SPECTROCHEM, Baton Rouge, LA 2017-Present
▪ Carry out different experiments for clients
POSTDOCTORAL RESEARCHER – AUDUBON SUGAR INSTITUTE, ST. GABRIEL, LA 2015-2017
▪ WORK WITH THERMOSET RESINS USING BYFPRODUCTS FROM SUGARCANE
SUBMITTED INVENTIONS TO THE LSU AGCENTER FOR POLYESTERS, EPOXIDE, AND COMPOSITE MATERIALS
INDEPENDENT CONTRACT CHEMIST – NEW ORLEANNS BIOINNOVATION CENTER, New Orleans, LA 2015-2016
▪ INSTALLED GAS SENSOR USING AN OPEN SOURCE ELECTRONIC PROTOTYPING PLATFORM CALLED ARDUINO
▪ WORKED ON INSTALLING SUPERCRITICAL FLUID GAS CHROMATOGRAPHY INSTURMENT
LOUISIANA STATE UNIVERSITY – DEPARTMENT OF CHEMISTRY, BATON ROUGE, LA 2008-2014
GRADUATE RESEARCHER (2008F2014)
▪ Design protocol for development of instrumentation to be utilized in High Throughput Screening (HTS).
▪ Utilize UV LiGA technology to develop microfabrication methods and create high aspect ratiomicrostructures.
▪ Characterize samples using TEM, DLS, UVFVis Spectroscopy, XPS, SEM, and AFM instruments.
MASTER TEACHING ASSISTANT (2012)
▪ Conducted weekly meetings with all first year Teaching Assistants and reviewed laboratoryprocedures.
▪ Supervised first year TAs and coordinated performance reviews andevaluations.
TEACHING ASSISTANT (2008F2012)
▪ Taught undergraduate level Chemistry laboratories, including two semesters of HonorsChemistry.
BASE OPERATORS, INC., LAKE CHARLES, LA 2011-2014
DIRECTOR
▪ Lead research and development of naturalproducts.
▪ Develop strategic and marketing plans for allproducts.
▪ Design and maintain website and marketing materials forproducts.
NATURAL ADVANTAGE, OAKDALE, LA 2006
CHEMIST
▪ Identified substances utilizing gas chromatography to perform various chemicalreactions.
▪ Managed research and development of products and implemented new organizationalpolicies.
▪ Analyzed procedures and made recommendations for changes to save time andmoney.
EDUCATION
Doctor of Philosophy, Chemistry, Louisiana State University, December 2014
Concentration in Analytical and Bioanalytical Chemistry
Master of Science, Chemical and Environmental Sciences, McNeese State University, 2008
Concentration in Oyster and Wastewater analyses using Gas Chromatography Mass Spectrometry
Completed one year as Microbiology lab TA for Department of Biology (2007D2008)
Bachelor of Science, Chemistry, University of Louisiana, 2005
2. Michael D. Vincent
Resume, Page 2
PUBLICATIONS AND PRESENTATIONS
• "Fabrication and characterization of stable hydrophilic microfluidic devices prepared via the in
situ tertiaryF amine catalyzed Michael addition of multifunctional thiols to multifunctional
acrylates “Bounds, Christopher; Upadhyay, Jagannath; Totaro, Nicholas; Thakuri, Suman; Garber,
Leah; Vincent, Michael; Huang, Zhaoyang; Hupert, Mateusz; Pojman, John. ACS Applied Materials &
Interfaces. ACS Appl. Mater. Interfaces 2013, 5, 1643F 1655.
• Vincent, Michael D., and Joseph Sneddon. "Nonylphenol: An overview and its determination in
oysters and wastewaters and preliminary degradation results from laboratory experiments."
Microchemical Journal 92.1 (2009): 112FFF118.
• Sneddon, Joseph, and Michael D. Vincent. "ICPFFFOES and ICPFFFMS for the Determination of
Metals: ApplicationtoOysters."AnalyticalLetters41.8(2008):1291FFF1303.
• Thibodeaux, Chad A., Michael D. Vincent, and Joseph Sneddon. "Determination of Cadmium,
Cobalt, and Lead in Oysters From Southwest Louisiana by Flame Atomic Absorption
Spectrometry." Spectroscopy Letters 43.7/8 (2010):524FFF527.
• Presentation at Pittcon 2012 Orlando, Florida Microfabrication of a PolymerFFFBased
MultiFFFChannel Fluidic Network for High Throughput Processing for Drug Discovery Michael D
Vincent, Louisiana State University, Mateusz L Hupert, Daniel S Park, Varshni Singh, Steven A
Soper.
• Presentation at International Student Conference on Microtechnology: research highlights –
networking – career building, IMTEK – Department of Microsystems Engineering, University of
Freiburg, Germany, 8th – 14th October 2012 Nanofabrication Techniques used in the Production
of Devices for BioFAnalytical Applications.
AFFILIATIONS
Student Government M LSU, Graduate School President and Former Senator and Treasurer
Consulat général de France à La NouvelleMOrléans, Chef d’Ilot 8
Alliance française de Lafayette, President
Louisiana State University Friends of French,
VicePresident Lafayette Farmers and Artisans
Market, Secretary Louisiane Acadie, Board
member
FELLOWSHIPS AND AWARDS
World Class University Fellow, Ulsan National Institute of Science and Technology, South Korea, 2013
National Science Foundation East Asia Pacific Summer Institute Fellowship, South Korea, 2012
Attendee, International Conference at Pohang University of Science and Technology, South