MesoBotox: a New Technique in Aesthetic Treatments”: a lecture by Dr. Naya Hassan in “the Sixth Scientific Conference for Dermatology and Cosmetic Surgery” that was held in La Mira Resort, Latakia, Syria.

1. MesoBotox
(MicroBotox)
a New Technique for Aesthetic
Treatments
By:
Naya Hassan

2. What is Mesobotox?
MESO BOTOX

3.  Mesotherapy stimulates the skin to self-renewal by the stitches of fine
needles.
 Botulinumtoxin relaxes the muscles and smoothes out the overlying skin.
What is Mesobotox?
Mesobotox unites the advantages of both treatments
The application of botulinum to skin by papule needle injection into the
dermis of the skin.
Meso + Botox?
Dr. Naya Hassan

4. Injection
Techniques
Mesotherapy Gun
Microneedling
Botox Syringe
Dr. Naya Hassan

5.  Injection botox into the dermis of the skin
(not muscles)  preservation of a certain
degree of facial mobility 
more aesthetic result.
 toxins are more dilute.
 relax the orbicular muscles.
(Botox can’t be used for this).
Mesobotox vs Botox
Dr. Naya Hassan

6. Botox
Mesobotox
Dr. Naya Hassan

7. Advantages
 reduce the action of:
- sweat and sebaceous glands.
- superficial layer of facial muscles.
 improved sheen of the face with smooth skin, tighter pores
and yet the ability to move all the deeper muscles of the face
thus retaining a natural, non “plastic” appearance.
 One of the consequences of aging in humans is that natural body
openings progressively close. At a facial level, it is very common to see
this effect in the eye and mouth.
The main objective of Mesobotox is to relax the good muscles
(orbicular muscles) to cause the reopening of orifices.
Dr. Naya Hassan

8. Injection Technique
1- Cleansing of facial skin.
2- Careful and detailed visual assessment of the
patient's face: visual assessment and palpation of muscles.
3- Accurate Assessment of Appropriate Application:
“Excess” areas should be identified with dots or small circles.
“Depressed” areas, wrinkles and lines should be identified
with dashes or “line shadowing”.
Dr. Naya Hassan

9. FORMULA 1 - High Concentration 100U Botulinum Toxin 1ml
Physiological Saline.
FORMULA 2 - Standard Concentration: 100U Botulinum Toxin 5ml
Physiological Saline 0.15ml Xylocaine 2% with adrenaline.
FORMULA 3 - Diluted Botulinum Toxin 100U Botulinum Toxin 7ml
Physiological Saline 0.2ml Xylocaine 2% with adrenaline.
FORMULA 4 - Highly-Diluted Botulinum Toxin: Used in
microinjections into enlarged pores in nose and chin 100U Botulinum
Toxin 1ml Physiological Saline.
FORMULA 5 - “Mesolift and Botox” Combination: 10IU Botulinum
Toxin - diluted in a 5ml syringe with procaine + vitamin C
Dr. Naya Hassan

10.  Highly concentrated Botulinum Toxin should be used in short
and thick muscles, whereas the diluted botulinum Toxin should
be used in flat and thin muscles.
The injection of the diluted toxin on a short
muscle always implies a certain degree of
inaccuracy and uncertain results. On the
contrary, a greater and inaccurate diffusion of
the product is preferred in flat muscles.
Dr. Naya Hassan

11. If injections are too superficial, papules
will turn into vesicles and the injected
drugs will remain at a superficial dermal
level with virtually no underlying effect.
Mesobotox results last 4-6 months
Dr. Naya Hassan

12. Disadvantages
 Pain: “A topical anesthetic can be applied”.
Usually disappears within a day or two.
 Bruising & Swelling: “The most frequent reaction”
These irritations usually clear within two weeks.
 Itch: A minor itch that lasts from a few hours to a few days.
Rare Sideeffects:
- Temporary areas of numbness and skin discoloration.
- Hematomas.
- Scarring at the site of the injection.
- Infection.
Dr. Naya Hassan

13. Results
Dr. Naya Hassan

14. Neck
Dr. Naya Hassan

15. Before
After
Dr. Naya Hassan

16. Before After
Dr. Naya Hassan

17. Before After
Dr. Naya Hassan

18. Before After
Dr. Naya Hassan

19. AfterBefore
Dr. Naya Hassan

20. Before After
Dr. Naya Hassan

21. Before After
Dr. Naya Hassan

22. “The MesoBotox technique preserves what
is natural”
“MesoBotox is about achieving beauty, but
with no traces of Botulinum Toxin ever being
used!”
B Hertogz

23. Thank
You!
Dr. Naya Hassan

24. referances- https://aestheticsjournal.com
- https://www.medicalnewstoday.com
- What Is Mesotherapy Treatment?: Published Wednesday 30 January 2008
By Sherry King
- F Gao, Y Liu, Y He, Y Wang, X Shi, G Wei, ‘Hyaluronan oligosaccharides promote excisional wound healing through enhanced
angiogenesis.’ Matrix Biologu 29 (2010), 107-116.
- JC Geesin, LJ Hendricks, PA Falkenstein, JS Gordon, RA Berg. ‘Regulation of collagen synthesis by ascorbic acid:
Characterization of the role of ascorbate- stimulated lipid peroxidation.’ Archives of Biochemisty and biophysics 290 (1991), 127-
132.
- Rose, DJ Goldberg, ‘Safety and efficacy of intradermal injection of botulinum toxin for the treatment of oily skin’ Dermatological
Surgery, 39 (2013), 443-448.
- AR Shah, ‘Use of intradermal botulinum toxin to reduce sebum production and facial pore size’, Journal of Drugs in Dermatology,
7 (2008), 847-850.
- C Petchnagaovilai, ‘Midface lifting with botulinum toxin: intradermal technique’, Journal of Cosmetic Dermatology, 8 (2009), 312-
316.
- C Le Louarn. ‘Botulinum toxin A and facial lines: The variable concentration’, Aesthetic Plastic Surgery, 25 (2001), 73-84.
- MI Tammi, AJ Day, EA Turley, ‘Hyaluronan and homeostasis: A balancing act’, Journal of Biological Chemistry, 277 (2002), 4581-
4594.
- H Kurzen, KU Schallreuter. ‘Novel aspects in cutaneous biology of acetylcholine synthesis and acetylcholine receptors’,
Experimental Dermatology, 13 (2004, 27-30. H Kurzen, KU Schallreuter.
- E Geddoa, AK Balakumar, TRF Paes, ‘The successful use of botulinum toxin for the treatment of nasal hyperhidrosis’,
International Journal of Dermatology 47 (2008) 1079-1080.
- SH Chang, HH Tsai, WU Chen, WR Lee, PL Chen, TH Tsai.‘The wrinkles soothing effect on the middle and lower face by
intradermal injection of botulinum toxin type A’, International Journal of Dermatology 47 (2008), 1287-1294. SH Chang, HH Tsai,
WU Chen, WR Lee, PL Chen, TH Tsai.
Dr. Naya Hassan