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MEGHA SURESH
55 Park Drive Apt. G 4, Boston, MA - 02215 ●meghasuresh91@gmail.com ●617-992-4333
WORK EXPERIENCE:
 Intern 09/2015-04/2016
(Modeling and Simulation Group, DMPK, Takeda Pharmaceuticals, Cambridge, MA)
 Proficient in polymer conjugate synthesis and purification through dialysis.
 Adept at formulation and characterization of polymer-based nanoparticles through dynamic light scattering and
transmission electron microscopy.
 Collaborated with cross-functional teams for identification of critical physicochemical and micro-environmental
parameters involved in nanoparticle uptake in spheroids models through fluorescence-based cell-uptake studies and
confocal microscopy.
 Graduate Research Assistant 12/2013-04/2016
(Dr. Mansoor Amiji’s Laboratory of Biomaterials and Nano-Delivery systems, Northeastern University,
Boston, MA)
Master’s Thesis Project: Successfully developed a co-culture 3 dimensional in vitro model of pancreatic cancer as a
mimic of inflammatory, hypoxic and cancer stem cell signaling in cancer and formulated a polymeric microRNA
delivery platform to induce apoptotic and tumor suppressive effects.
Heavily involved in training master’s students in lab techniques listed below. Providing continued guidance to students
to facilitate success of their new projects.
Skills acquired:
Cell culture experience:
Expertise in mammalian cell culture and aseptic technique (tumor, immune and stromal cell lines), cryopreservation,
thawing, maintenance and expansion of cell lines, bacterial cell culture, extensive experience in spheroid plating and
analysis
Nucleic acid-based experience:
Strong experience in nucleic acid techniques including RNA extraction, RT-PCR, qPCR, gel electrophoresis to assess
expression of inflammatory, hypoxic and cancer stem cell markers at the gene level.
Experienced in Taqman transfection and nucleic acid labeling assays.
Protein-based experience:
Protein extraction and concentration, bicinchonic acid assay, western blot and SDS-PAGE electrophoresis to study
expression of inflammatory and hypoxia markers at protein level.
Competent in immuno-fluorescence and fluorescence-activated cell sorting to analyze stem cell markers on 2D and 3D
In vitro tumor models, and immunohistochemistry to compare expression on orthotopic pancreatic tumor samples.
Cell-based assays:
Developed competency in uptake studies through nucleic acid and polymer labeling and optimized transfection
protocols to evaluate delivery.
Devised protocols for cytotoxicity assays to evaluate RNA interference-induced cell death across various in vitro models.
Formulation/other experience:
▪ Preparation & analysis of Polymeric Nanoparticles ▪ Confocal Microscopy ▪ Dynamic Light Scattering
▪ Polymer synthesis ▪ TEM ▪ Affinity Chromatography
▪ Enzyme Kinetics
In vivo techniques:
Intravenous, Intra-peritoneal and Subcutaneous Injections; Blood collection; Tumor measurement; Tissue collection;
Oral gavage; Basic Animal handling.
Software: Gaining proficiency in MATLAB, Python.
Adept at MS Office - Word, Excel, PowerPoint; GraphPad; ImageJ, Malvern Zetasizer and Zen Confocal microscopy
software.

2. 2
 Teaching Assistant
(Master’s Level Pharmaceutical Sciences Lab, Northeastern University, Boston, MA) 09/2014 to 04/2015
Awarded an assistantship on account of academic standing to work with professor to set-up, demonstrate and teach
aforementioned laboratory skills to master’s students.
 Student Trainee
(Meyer Organics Private Limited, Mumbai, India) 06/2012 to 06/2012
 Successfully completed on-site training and worked in QA, QC, Production departments.
 Gained proficiency in QC analysis of tablets including dissolution, disintegration, friability, hardness, diameter, thickness
and weight variation techniques.
 Developed a consolidated understanding of SOPs, and large-scale manufacturing, packaging and labeling of solid oral
dosage forms.
EDUCATION:
▪ M.S in Pharmaceutical Sciences with Specialization in Pharmaceutics and Drug Delivery (with Thesis) GPA: 3.76
Northeastern University, Boston, MA Expected date of graduation: 04/2016
Relevant Coursework:
▪ Advanced Pharmacokinetics and Toxicology ▪ Tissue Engineering
▪ Pharmacokinetics and Drug Metabolism ▪ Cellular Physiology
▪ Concepts in Pharmaceutical Sciences ▪ Advanced Physical Pharmacy
▪ Experimental Design and Biometrics ▪ Drug discovery and development
▪ Advanced Drug Delivery Systems ▪ Human Anatomy and Physiology
▪ Bachelor of Pharmacy GPA: 3.64
S.N.D.T. Women's University, Mumbai, India 2013
Relevant Coursework:
▪ Pharmaceutical Chemistry ▪ Pharmaceutical Analysis
▪ Pharmacology ▪ BioPharmaceutics
▪ Practical training in preparing and evaluating powders, tablets, creams, ointments, gels, injectables, suspensions and
emulsions.
HONORS, AWARDS, PRESENTATIONS AND LEADERSHIP EXPERIENCE:
▪ Recipient of Student Fellowship at World Preclinical Congress 2015 and presenter, Boston, MA 04/2015
▪ Recipient of Shevell/Cohen Cancer Research Award, Northeastern University, Boston, MA 05/2015
▪ Recipient of Discovery on Target 2015 Student Fellowship, Boston, MA 07/2015
▪ Presented at AAPS-NERDG 2015 Conference, Farmington, Connecticut 07/2015
▪ Teaching Assistantship Award, Northeastern University, Boston, Massachusetts 09/2014 – 04/2015
▪ Invited to present at AAPS Annual Meeting and Exposition, Orlando, Florida 10/2015
▪ President, Northeastern University AAPS Student Chapter 01/2015-09/2015
▪ Huntington Hundred – Outstanding Graduate Student Award, Northeastern University, Boston, MA 04/2016
PUBLICATIONS:
Exosome mediated communication within the tumor microenvironment; Lara Milane, Amit Singh, George Mattheolabakis,
Megha Suresh, Mansoor M. Amiji; Journal of Control Release, July 2015.
Reversing Epigenetic Mechanisms of Drug Resistance in Solid Tumors using Targeted MicroRNA Delivery; Melissa
Berman, George Matthiaolabakis, Megha Suresh, and Mansoor Amiji; Expert Opinion on Drug Delivery – Communicated
in February 2016.