1. EVAR was found to have a 3% reduced 30-day mortality but increased long-term reintervention rates compared to open repair in trials. However, the rate of reintervention continues to increase over time for both methods.
2. While EVAR provides an initial survival benefit for ruptured AAA, the results are inconclusive due to heterogeneity and many patients still require open repair due to anatomical limitations.
3. Open repair remains the gold standard treatment for AAA due to the increasing long-term reintervention rates with EVAR and concerns about the overuse and liberal guidelines for device usage not aligning with patient risk factors and life expectancy.
Repositioning the future of evar real life experience with the gore excluder ...uvcd
Repositioning the future of evar real life experience with the gore excluder featuring c3 delivery system and one year results of the european registry
Repositioning the future of evar real life experience with the gore excluder ...uvcd
Repositioning the future of evar real life experience with the gore excluder featuring c3 delivery system and one year results of the european registry
Review of Randomized Controlled Trials Comparing Endovenous Thermal and Chemi...Vein Global
By: Edward G. Mackay, MD
Visit VeinGlobal at http://www.veinglobal.com/ for more presentations and videos on this topic, or for more information on venous disease news, education and research.
DETAILS OF EVIDENCE TAVI FROM ITS EXISTENCE IN INTERVENTIONAL CARDIOLOGY TO THE SURTAVI REGISTRY ..AS AN OPTION FROM HIGH RISK UNOPERABLE PATIENTS TO INTERMEDIATE AND LOW RISK PATIENTS
Fundación EPIC _ Tendencias actuales en TAVI y desafíos futuros.Fundacion EPIC
Presentación de la ponencia "Tendencias actuales en TAVI y desafíos futuros" por el Doctor Rodés-Cabau en los Diálogos EPIC_Retos Clínicos en Válvulas Transcatéter/ Clinical Challenges in TAVR today, el 10 de Mayo de 2018 en Barcelona (España)
Review of Randomized Controlled Trials Comparing Endovenous Thermal and Chemi...Vein Global
By: Edward G. Mackay, MD
Visit VeinGlobal at http://www.veinglobal.com/ for more presentations and videos on this topic, or for more information on venous disease news, education and research.
DETAILS OF EVIDENCE TAVI FROM ITS EXISTENCE IN INTERVENTIONAL CARDIOLOGY TO THE SURTAVI REGISTRY ..AS AN OPTION FROM HIGH RISK UNOPERABLE PATIENTS TO INTERMEDIATE AND LOW RISK PATIENTS
Fundación EPIC _ Tendencias actuales en TAVI y desafíos futuros.Fundacion EPIC
Presentación de la ponencia "Tendencias actuales en TAVI y desafíos futuros" por el Doctor Rodés-Cabau en los Diálogos EPIC_Retos Clínicos en Válvulas Transcatéter/ Clinical Challenges in TAVR today, el 10 de Mayo de 2018 en Barcelona (España)
Long-Term Durability of Transcatheter Aortic Valve ProsthesesShadab Ahmad
Assessments of valve function in the early randomized trial cohorts and registries have consistently shown preserved valve function up to 5 years after TAVR. However, it is well recognized that structural valve degeneration (SVD) with surgical aortic valve bioprostheses is usually not seen until 5 to 10 years post-procedure, and data in this time frame following TAVR are very sparse
Annual Academic Conference
SLSVS 23
Joel Arudchelvam
MBBS, MD ( SUR ), MRCS (ENG), FCSSL
Consultant Vascular and Transplant Surgeon
Aortic aneurysms
Abnormal focal dilatation of a vessel of more than 50 % of its normal diameter
Abdominal aorta more than 3 cms (normal diameter - 2 cms)
Open AAA repair
Endo Vascular Aneurysm Repair (EVAR)
Arch de-branching
Sri Lankan Experience
15 Vascular and transplant units
Emergency AAA repair
Open TAA repair
Future directions
Similar to Medium and long term results following evar success or disappointment (20)
Have you ever wondered how search works while visiting an e-commerce site, internal website, or searching through other types of online resources? Look no further than this informative session on the ways that taxonomies help end-users navigate the internet! Hear from taxonomists and other information professionals who have first-hand experience creating and working with taxonomies that aid in navigation, search, and discovery across a range of disciplines.
This presentation, created by Syed Faiz ul Hassan, explores the profound influence of media on public perception and behavior. It delves into the evolution of media from oral traditions to modern digital and social media platforms. Key topics include the role of media in information propagation, socialization, crisis awareness, globalization, and education. The presentation also examines media influence through agenda setting, propaganda, and manipulative techniques used by advertisers and marketers. Furthermore, it highlights the impact of surveillance enabled by media technologies on personal behavior and preferences. Through this comprehensive overview, the presentation aims to shed light on how media shapes collective consciousness and public opinion.
This presentation by Morris Kleiner (University of Minnesota), was made during the discussion “Competition and Regulation in Professions and Occupations” held at the Working Party No. 2 on Competition and Regulation on 10 June 2024. More papers and presentations on the topic can be found out at oe.cd/crps.
This presentation was uploaded with the author’s consent.
Acorn Recovery: Restore IT infra within minutesIP ServerOne
Introducing Acorn Recovery as a Service, a simple, fast, and secure managed disaster recovery (DRaaS) by IP ServerOne. A DR solution that helps restore your IT infra within minutes.
0x01 - Newton's Third Law: Static vs. Dynamic AbusersOWASP Beja
f you offer a service on the web, odds are that someone will abuse it. Be it an API, a SaaS, a PaaS, or even a static website, someone somewhere will try to figure out a way to use it to their own needs. In this talk we'll compare measures that are effective against static attackers and how to battle a dynamic attacker who adapts to your counter-measures.
About the Speaker
===============
Diogo Sousa, Engineering Manager @ Canonical
An opinionated individual with an interest in cryptography and its intersection with secure software development.
Sharpen existing tools or get a new toolbox? Contemporary cluster initiatives...Orkestra
UIIN Conference, Madrid, 27-29 May 2024
James Wilson, Orkestra and Deusto Business School
Emily Wise, Lund University
Madeline Smith, The Glasgow School of Art
16. 16Schanzer A - Circulation 2011;123:2848
EVAR – Instructions for use (IFU)
17. 17Schanzer A - Circulation 2011;123:2848
Aneurysm sac enlargement following EVAR
conservative IFU liberal IFU date of implantation
n = 10.228 (1999-2008)
AAA Ø < 55 mm 59 %
Conservative IFU 42 %
Liberal IFU 69 %
Sac enlargement at 5 yrs 41 %
18. 18Wyss TR – Ann Surg 2010;252:805
Complications following EVAR
n = 848 (EVAR 1 & 2) mean F-U 4.8 a
Late rupture: 27 (3 % - mortality 67 %) Crude rate 0.7/100 pt.yr
HR complication/rupture: 8.83 (p<0.0001)
19. 19
CAESAR trial – Surveillance vs small AAA repair
AAA 4.1 to 5.4 cm - n=360 – f-u 54 months
Cao P – Eur J Vasc Endovasc Surg 2011;41:13
24. 24
Lesperance K - JVS 2008;47:1165
National Inpatient SampleMedicare Inpatient Database
Mureebe L - JVS 2008;48:1101
Visser JJ - Radiology 2007;245:122
EVAR for ruptured AAA - mortality
Review - n=478 - EVAR vs OPEN = 22% vs 38%
25. 25
Diagnosis: rAAA
permissive hypotension, no intubation, sonography
OPEN
EVAR suitable & available
EVAR
CTA
no yes
Stable hemodynamicsUnstable hemodynamics
Treatment algorithm for ruptured AAA
26. 26
Consideration
for repair
Assessment of fitness Assessment of morphology
Fit for repair
optimisation Standard
AAA repair
OPEN or EVAR
Transabdominal
Unfit for repair
optimisation
Fit
Unfit for
OPEN or EVAR
Manage conservatively
Suitable for
EVAR
Not suitable for
EVAR
Custom Open Laparoscopic
Retroperitoneal
Patient preference
Center preference
> 8cm
urgent
Guidelines from the European Society for Vascular Surgery – EJVES 2011;41:S1
Treatment algorithm for unruptured AAA
27. 27
Choosing the best management of AAA for individual pts.
Cronenwett JL – Lancet 2005;365:2156
28. 28
Conclusions
The anatomical suitability for EVAR is a proxy for
subsequent complications and potential aneurysm-
related mortality
The rate of re-intervention continues to increase with
time regardless of the device
The compliance with EVAR device guidelines is far too
liberal (demand & supply, profiling, curiosity,
industrial interests)
Patients with acceptable operative risk and longer
life-expectancy are the best candidates for open
repair
29. 29
Conclusions
High-risk patients with marginal anatomical suitability
or short life-expectancy will not benefit from EVAR
Early repair of small aneurysms gives no substantive
advantage over surveillance
The promising results of EVAR for ruptured AAA are
not fairly conclusive because of the heterogenity of
the cases and significant logistic limitations
Whilst the overall management of abdominal aortic
aneurysms has undoubtedly benefited from the
introduction of stent-grafts, open repair currently
remains the gold standard treatment
Editor's Notes
There was no significant difference in cumulative mortality for open vs endovascular repair (hazard ratio, 0.7; 95% confidence interval, 0.4-1.1; log-rank P = .13).
Kaplan-Meier curve of survival free of death or reintervention after open surgical repair (OSR) or endovascular aneurysm repair (EVAR).
Kaplan–Meier estimates for time to first cardiovascular event stratified by randomised group.
Multiple correspondence analysis (MCA); the original variables are represented in a space defined by factorial axes, which are characterized by a percentage of inertia (i.e. the amount of total variability explained by the axis itself). The distance between points indicates the dissimilarities between categories, while categories that plot close to each other are statistically related and are similar with regard to the pattern of relative frequencies.12 COPD, chronic obstructive pulmonary disease.
Hilpold, Hermann – 04.08.33
Aortic aneurysm sac freedom from enlargement after endovascular aortic repair stratified according to (A) conservative instructions for use (IFU), (B) liberal instructions for use, (C) time-dependent instructions for use, and (D) year of procedure performed before or after January 1, 2004.