This document discusses the cardiovascular health benefits of omega-3 polyunsaturated fatty acids (PUFAs). It summarizes that omega-3 PUFAs from foods like fish, flaxseeds and nuts have anti-inflammatory and inflammation resolving effects. They act through multiple mechanisms such as inhibiting inflammatory gene expression, producing anti-inflammatory mediators, and altering cell membrane composition. Omega-3 PUFAs help prevent cardiovascular disease by reducing arrhythmias, lowering triglycerides, decreasing endothelial activation and vascular smooth muscle growth, and stabilizing atherosclerotic plaques.