This document provides biographical and professional information about Mukulesh Baruah, including his educational background, research interests, professional experience, skills, awards, publications, and contact information. It summarizes that he is an Associate Professor in the Department of Chemistry at Apex Professional University in India, with research interests in organic synthesis, medicinal chemistry, and natural products. He has over 30 publications and extensive professional experience in both academia and industry.

1. Mukulesh Baruah, Ph.D.
Associate Professor
Department of Chemistry
Apex Professional University
Pasighat, East Siang District.
Arunachal Pradesh-791102
India.
Phone:+91 9706527537 or +91 8119961330
mukulesh.baruah@gmail.com
Research Overview
• Synthetic methodologies in organic chemistry.
• Diverse medicinal chemistry background as drug discovery for multiple therapeutic areas, viz,
hormone dependent (breast and prostate) cancers and preparation of drug intermediates.
• Isolation, structure elucidation of natural products and total synthesis of selected targets.
• Contribute some part in a research project for discovery of HIV vaccine.
• Synthesis of fluorescent probes for biologically important ions and molecules.
• Synthesis of fluorescent enzyme substrate for studying enzyme kinetics.
Professional Experience
Apex Professional University
Pasighat, Arunachal Pradesh, India
Associate Professor
February, 2016 – Present
ChemCare
Guwahati, Assam, India
Research and Production Manager
June, 2012- December, 2015
►Preparation of bleaching agents, homecare products and fluorescent dyes.
South Dakota State University
Department of Chemistry and Biochemistry,
Brookings, SD, USA
Postdoctoral Research Associate
Oct, 2009- Nov, 2011.
► Design, Synthesis and biological evaluation of steroid based compounds as potential cytotoxic
agents for hormone dependent cancers.

2. University of Texas Health Science Center at Houston
Houston, TX, USA
Postdoctoral Research Associate
Sept, 2007 -Sept, 2009
► Synthesis and modification of peptides and proteins for producing catalytic antibodies in mice
(antibody engineering) in the research of co-valent vaccination for HIV and autoimmune disease.
Antibody generation to prevent aggregation of amyloid beta 40 and 42 for treatment of Alzheimer's
disease.
Molecular Mechanism of Apoptosis in Cancer Cells.
McMaster University
Department of Chemistry,
Hamilton, ON, Canada.
Postdoctoral Research Associate
Jan, 2007-Aug, 2007.
►Phosphorus derived Organocatalysis.
Catholic University
Department of Chemistry,
Leuven, Belgium
Postdoctoral Research Associate
Oct, 2003 – Dec, 2006
► Synthesis of fluorescent probes for biologically important ions and molecules.
Synthesis of fluorescent enzyme substrate for studying enzyme kinetics.
National Taiwan Normal University
Department of Chemistry,
Taipei, Taiwan.
Postdoctoral Research Associate
Nov, 2002 – Apr, 2003
►Vanadyl Catalyzed Asymmetric Synthesis
Aarhus University
Department of Chemistry,
Aarhus, Denmark.
Postdoctoral Research Associate
Nov, 2000 – Oct, 2001
► Solution phase Combinarorial Chemistry.
Council of Scientific and Industrial Research (CSIR, India)
Jorhat, Assam, India.
Senior Research Fellow
Sept, 1996 – Sept, 2000
►For pursuing PhD. in Synthetic Methodologies and Cycloaddition Chemistry.

3. Education
Ph.D. (Organic Chemistry)
Thesis Title: "Some Functional Group Transformations and Aziridines in Cycloaddition Reaction."
Supervisor: Dr. Jagir S. Sandhu.
North Eastern Institute of Science and Technology / Dibrugarh University, Assam, India
1995-1999
M.Sc. in Chemistry (Organic Special.)
Dibrugarh University, Assam, India
1993-1995
B.Sc. in Chemistry
Dibrugarh University, Assam, India
1989-1992
Technical Skills
• Multiple step reactions in Organic synthesis.
• Electrophoresis, Elisa, Western-blotting, Immunohistochemistry.
• Operation of NMR, Mass (ESI, EI, CI), IR
• HPLC, AFM, and Spectrophotometer/Fluorometer
Awards
1] J. M Borthakur Memorial award in J.B. College, Jorhat, for first position in Chemistry (Major) B.Sc.
Final Examination, 1992.
2] J. N Bora Memorial award in JB College, Jorhat, for first position in Chemistry (Major) B.Sc Final
Examination, 1992.
3] Senior Research Fellowship for Council of Scientific and Industrial Research (CSIR, India) for research
to do Ph.D. 1997-2000.
4] Research Associate of CSIR (India) in October 2000.
Conferences attended with Poster Presentation
• International conference on OLED and PLED. Dec 2002, Taipei, Taiwan.
• 7th Sigma-Aldrich Organic Synthesis Meeting. Dec 2003, Spa, Belgium

4. • IDO-meeting. "Calcium imaging: From Probes to Physiology". Nov 2004, Leuven, Belgium.
• 9th
International Conference on Methods and Applications of Fluorescence (MAF9) Sept
2005, Lisbon, Portugal.
• FNRS contact group (A meeting of fluorescent technology). Sept 2005, Brussels, Belgium.
• 9th Sigma-Aldrich Organic Synthesis Meeting. Dec 2005. Spa, Belgium. Poster presentation.
• 32nd National Medicinal Chemistry Symposium, Minneapolis, MN, USA, June 6th-
June9th
2010.
Cucurbitane and estrone analogs: Targeting AR, HSP90, COX II, NFkB, and iNOS receptors for
prostate cancer treatment.
Nichole Rice, Mukulesh Baruah, and Fathi Halawish
• 241st National ACS Meeting and Exposition March 2731, 2011 Anaheim, CA; USA.
Novel estrogen and cucurbitane analogs: Potential drug candidates targeting breast cancer.
Abdulrhman Alsayari, Fathi Halaweish, Mukulesh Baruah.
241st National ACS Meeting and Exposition March 2731, 2011 Anaheim, CA; USA.
List of Publications
1] Baruah, M.; Huntimer, E. D.; Mahmoud, S. A.; Hoppe, A. D.; Halaweish, F. T. Selective BODIPY®
Based
Fluorescent Chemosensor for imaging Pb2+
ion in living cells. Tetrahedron. Letters. 53 (33), 4273-4275,
2012.
2] Baruah M. Facile synthesis of bis(indolyl)alkanes catalyzed by Cu(ClO4)2.6H2O under solvent free
conditions, Letters in Organic Chemistry, 8 (7), 461-463, 2011.
3] Boens N, Qin W, Baruah M, De Borggraeve WM, Filarowski A, Koll A, Smisdom N, Ameloot M,
Crovetto KL, Talavera EM, and Alvarez-Pez JM. Rational Design, Synthesis Spectroscopic and
Photophysical Properties of a Visible Light Excitable, Ratiometric, Fluorescent, Near-Neutral pH
Indicator Based on the BODIPY.Chemistry: A European Journal, 17, 10924-10934, 2011.
4] Ameloot R, Roeffaers M, Baruah M, De Cremer G, Sels B, De Vos DE, and Hofkens J. Towards direct
monitoring of discrete events in a catalytic cycle at the single molecule level. Photochem Photobiol Sci.
8(4): 453-456, 2009.
5] Martínez VM, De Cremer G, Roeffaers MB, Sliwa M, Baruah M, De Vos DE, Hofkens J, and Sels BF.
Exploration of single molecule events in a haloperoxidase and its biomimic: localization of halogenation
activity. J Am Chem Soc. 130(40):13192-13193, 2008.
6] Qin W, Baruah M, Sliwa M, Van der Auweraer M, De Borggraeve WM, Beljonne D, Van Averbeke B,
and Boens N. Ratiometric, fluorescent BODIPY dye with aza crown ether functionality: synthesis,
solvatochromism, and metal ion complex formation. J Phys Chem A. 112(27):6104-6114, 2008.
7] Roeffaers MB, Ameloot R, Baruah M, Uji-I H, Bulut M, De Cremer G, Müller U, Jacobs PA, Hofkens J,
Sels BF, and De Vos DE. Morphology of large ZSM-5 crystals unraveled by fluorescence microscopy. J
Am Chem Soc. 130(17):5763-5772, 2008.

5. 8] De Cremer G, Roeffaers MB, Baruah M, Sliwa M, Sels BF, Hofkens J, and De Vos DE. Dynamic
disorder and stepwise deactivation in a chymotrypsin catalyzed hydrolysis reaction. J Am Chem Soc.
129(50):15458-15459, 2007.
9] Vallée RA, Baruah M, Hofkens J, De Schryver FC, Boens N, Van der Auweraer M, and Beljonne D.
Fluorescence lifetime fluctuations of single molecules probe the local environment of oligomers
around the glass transition temperature. J Chem Phys. 126(18):184902, 2007. [Also selected for
Publication in the May 21, 2007 issue of Virtual Journal of Nanoscale Science & Technology]
10] Baruah M, Qin W, Flors C, Hofkens J, Vallée RA, Beljonne D, Van der Auweraer M, De Borggraeve
WM, and Boens N. Solvent and pH dependent fluorescent properties of a dimethylaminostyryl
borondipyrromethene dye in solution. J Phys Chem A. 110(18):5998-6009, 2006.
11] Qin W, Baruah M, De Borggraeve WM, and Boens N. Photophysical properties of an on/off
fluorescent pH indicator excitable with visible light based on a borondipyrromethene-linked phenol.
Journal of Photochemistry and Photobiology A: Chemistry. 183(1-2):190-197, 2006.
12] Rohand T, Baruah M, Qin W, Boens N, and Dehaen W. Functionalisation of fluorescent BODIPY
dyes by nucleophilic substitution. JCSChem Commun (Camb). (3):266-268, 2006.
13] Qin W, Rohand T, Baruah M, Stefan A, Van der Auweraer M, Dehaen W, and Boens N. Solvent-
dependent photophysical properties of borondipyrromethene dyes in solution. Chemical Physics
Letters. 420(4-6):562-568, 2006.
14] Baruah M, Qin W, Vallée RA, Beljonne D, Rohand T, Dehaen W, and Boens N. A highly potassium-
selective ratiometric fluorescent indicator based on BODIPY azacrown ether excitable with visible light.
Org Lett. 7(20):4377-4380, 2005.
15] Qin W, Baruah M, Stefan A, Van der Auweraer M, and Boens N. Photophysical properties of
BODIPY-derived hydroxyaryl fluorescent pH probes in solution. Chemphyschem. (11):2343-2351, 2005.
16] Baruah M, Qin W, Basarić N, De Borggraeve WM, and Boens N. BODIPY-based hydroxyaryl
derivatives as fluorescent pH probes. J Org Chem. 70(10):4152-4157, 2005.
17] Basarić N, Baruah M, Qin W, Metten B, Smet M, Dehaen W, and Boens N. Synthesis and
spectroscopic characterisation of BODIPY based fluorescent off-on indicators with low affinity for
calcium. Org Biomol Chem. 3(15):2755-2761, 2005.
18] Qin W, Baruah M, Van der Auweraer M, De Schryver FC, and Boens N. Photophysical properties of
borondipyrromethene analogues in solution. J Phys Chem A. 109(33):7371-7384, 2005.
19] Baruah M, and Bols M. Substitution of a-azido ethers with Grignard reagents and its use in
combinatorial chemistry. J. Chem. Soc., Perkin Trans. 1 (4):509-512, 2002.
20] Baruah M, and Bols, M. An Azido-Hanessian Reaction. Synlett. 07: 1111-1112, 2002.
21] Gadhwal S, Baruah M, Prajapati D, and Sandhu J.S. Microwave-Assisted Regioselective Synthesis of
β-Aminoketones via the Mannich Reaction. Synlett. 03:341-342, 2000.
22] Gadhwal S, Baruah M, and Sandhu JS. Microwave Induced Synthesis of Hydrazones and Wolff-
Kishner Reduction of Carbonyl Compounds. Synlett. 10:1573-1574, 1999.

6. 23] Thakuria JA, Baruah M, and Sandhu JS. Microwave Induced an Efficient Synthesis of Alcohols via
Cross-Cannizzaro Reaction. Chemistry Letters. 28(9):995-996, 1999.
24] Baruah M, Boruah A, Prajapati D, and Sandhu JS. Bi or Cd-Induced Coupling of Sulfonyl Chlorides
with Allylic Halides. A Simple Synthesis of Allylic Sulfones. Synlett. 10: 1083-1084, 1998.
25] Baruah M, Prajapati D, and Sandhu JS. Regeneration of Carbonyl Compounds from Semicarbazones
Under Microwave Irradiations. Synthetic Communications. 28(22):4157-4163, 1998.
26] Boruah A, Baruah M, Prajapati D, and Sandhu JS. Cerium Catalyzed Michael Addition of 1,3-
Dicarbonyl Compounds Under Microwave Irradiation. Synthetic Communications. 28(4):653-658, 1998.
27] Baruah M, Hussain A, Prajapati D, and Sandhu JS. New and Efficient Method for the
Chemoselective Reduction of Azidoarenes and Aroylazides: Use of Zinc-Cobalt Chloride. Chemistry
Letters. 26(8):789-790, 1997.
28] Boruah A, Baruah M, Prajapati D, and Sandhu JS. The Efficient Chemoselective Reduction of Azides
to Primary Amines. Synlett. 11: 1253-1254, 1997.
29] Baruah M, Boruah A, Prajapati D, and Sandhu J.S. Bakers’ Yeast Mediated Chemoselective
Reduction of Azidoarenes. Synlett. 12:1193-1194, 1996.
30] Boruah A, Baruah M, Prajapati D, and Sandhu JS. Michael Reaction in the Solid State under
Microwave Irradiations. Chemistry Letters. 25 (11):965-966, 1996.
31] Baruah M, Boruah A, Prajapati D, Sandhu JS, and Ghosh AC. A new method for the chemoselective
reduction of aryl and aroylazides. Tetrahedron Letters. (26): 4559-4560, 1996.
32] Dane’s Diene: A review. Under preparation.
Additional Information
Reviewer for the journal: Synthetic Communications, since 2010.
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