1. The document discusses the challenges of implementing augmented intelligence in the life sciences industry. It notes that achieving the right human-AI partnership requires having the right intelligence, mindset, data, and expertise. 2. Three key challenges are highlighted - ensuring relevant data, developing deep subject matter expertise, and cultivating a growth mindset. Overcoming these challenges requires aligning human-centered solutions using the appropriate intelligence supported by data and relying on expert knowledge. 3. The hardest part of augmented intelligence in life sciences is implementing it in a way that improves clinical outcomes for healthcare providers and patients through better decision making and performance. This requires getting the right balance of intelligence, data, expertise, and mindset.

1. 1. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Augmented (Generative) Intelligence
in the Life Sciences:
The Hardest Thing
Matt Lewis, MPA
GLOBAL CHIEF ARTIFICIAL AND
AUGMENTED INTELLIGENCE OFFICER
matt.lewis@inizio.health | www.linkedin.com/in/matthewevanlewis
AI and augmented intelligence - Inizio

2. 2. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Disclosures
I am a partner in Inizio and have equity interests in the firm. I am a minority shareholder in both
Diviner, a startup focusing on forecasting biotechnology clinical trial outcomes, and AVOMD, a no-
code digital innovation form speeding time-to-clinical decisions
My comments are mine and mine alone. They are not the official, endorsed position of Inizio,
any firm in which I have or do not have an equity position, and have not been reviewed or
approved by anyone prior to this discussion

3. 3. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Engage
Medical
We are a global life sciences powerhouse
About Inizio
Global capabilities covering the full value chain from the drug development stage to post-launch.
Advisory
MarComms
DISCOVERY DEVELOPMENT PRELAUNCH LAUNCH POST LAUNCH
Creative communication
Medical communication
Public and media relations
Market access
HEOR and RWE
Medical engagement
Promotional engagement
Market research
Patient engagement
Scientific medical communications (incl. medical writing)
Expert engagement
Meetings & events
Clinical and medical education
Strategy and consulting

4. 4. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
4. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Gartner’s Definition of Augmented Intelligence
Augmented (generative) intelligence is a design
pattern for a human-centered partnership model
of people and artificial intelligence (AI)
working together to enhance cognitive performance,
including learning, decision making and new experiences.

5. 5. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Augmented (Generative) Intelligence
in the Life Sciences:
What Makes Human Partnership So Hard?
PRACTICAL
INTELLIGENCE
GROWTH
MINDSET
RELEVANT
DATA
DEEP AND BROAD
EXPERTISE

6. 6. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Data: It Ain’t What It Used To Be
1951 2000
40 years
to double
medical
knowledge
40 days
to double
medical
knowledge
2021 2050
PHYSICIAN TYPICALLY INTERACTS WITH
1 new person/day
PHYSICIAN TYPICALLY INTERACTS WITH
5 new people/day

7. 7. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Triarchic Intelligence
Multiple Types of
Intelligence
ANALYTICAL INTELLIGENCE
Mental steps or components
used to solve problems
CREATIVE INTELLIGENCE
Use of previous experience in
ways that foster insight
PRACTICAL INTELLIGENCE
Ability to read and
adapt to everyday life

8. 8. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Humans in
the Enterprise
Humans in
Regulated Industries
(Life Sciences)
You Can Take the Human Out of the Cave,
But You Can’t Take the Human’s Mind Out…
Humans in their
Natural Environment

9. 9. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Humans in
the Enterprise
Humans in
Regulated Industries
(Life Sciences)
You Can Take the Human Out of the Cave,
But You Can’t Take the Mindset Out of the Human…
Humans in their
Natural Environment
“
“
The human “default mindset” wired into our
brain 100,000 years ago is fear and scarcity.
It’s time for a mindset upgrade.
Peter Diamandis, Founder,
X Prize, Chairman of Singularity University

10. 10. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Right Expertise
Experience
Research
Education
Writing and
Publications
SUBJECT MATTER
EXPERTS
Greater than the
sum of their parts

11. 11. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Key elements of generative AI tech stack
Vertical AI applications
Generative AI applications tailored to solve industry-specific use
cases. May be embedded in larger enterprise software suites
Horizontal AI applications
Generative AI applications that solve cross-cutting functional
dept. use cases. May be embedded in enterprise software suites.
General productivity applications
Generative AI embedded in core office applications –
comms, Office suite, software development, etc.
Model infrastructure
Platforms for deployment, integration, training, optimization,
performance monitoring
Model Providers / Model APIs
Providers of foundation models who support downstream applications;
may also provide fine-tuned models and model infrastructure
Foundation Model training, Responsible AI
Approach & principles governing FM creation
Generative AI tech stack
Applications
Infrastructure
Text Code Image Video Audio Other
Vertical applications
Life sciences
Technology
Healthcare
Industrials/CPG
Other
Horizontal applications
Sales/mktg
HR
Legal
Finance
General productivity applications
Software dev
Office productivity
MLOps, model distribution
Model experimentation, prompting
Fine-tuned domain models
Foundation models
Foundation model training, (hopefully) Responsible AI
Closed-source
Open-source
Data modality
Focus of today’s talk

12. 12. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Aligning Human-Centered Solutions utilizing
the Right Intelligence supported by the Right
Data, Relying on the Right Expertise led by
Humans in the Right Mindset to Improve
(Cognitive Performance…Decision Making and)
Clinical Outcomes for HCPs and Patients
So, What’s The Hardest Thing,
for Augmented (Generative)
Intelligence in the Life Sciences?

13. 13. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Let’s Say What We Can Access/
What We Think Should Be Said
In the old world…

14. 14. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
14. INIZIO
Leveraging NLP, our data science team ingests the full corpus of
a scientific therapeutic footprint (>10,000
papers/posters/preprints)
We build a curated vocabulary for the project including key
terms, important concepts, and the like
Strategists evaluate competitive and contextual considerations,
and we produce a heatmap, where the interactive platform
illustrates how often the terms appear together in the same
sentence
Dark colors show terms that appear together many times
Drill-down functionality to review all sentences where the terms
appear together
Putting Our Best Foot Forward:
The Augmented Scientific Narrative

15. 15. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
In the old world, we were limited by our time and our
memory in identifying scientific and competitive intelligence

16. 16. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Augmented Identification of search
Terms, automated Screening and
auto-Summarization, Knowledge graph
• How the work gets done sees AI simplifying and
strengthening what is possible
• Team is able to get more done, faster, with outsized value
• Client can partner with Inizio on more than previously
possible
In the modern world, SMEs
collaborate with AI/GenAI to
augment the possible:
Intelligent Literature Monitoring

17. 17. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
In the old world, teams were lucky if they could figure
out what customers found insightful…

18. 18. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Private and Confidential.
The Advanced Analytics platform informs KOL
engagement with near real-time quantitative &
qualitative analysis and dynamic content
generation for Life Sciences Strategic Excellence
Field Medical Collaborative Intelligence
• Accelerate insight generation, engagement analysis,
geotargeting, and sentiment validation
• Communicate actionable insights to stakeholders with more
context and less bias in near real-time
• Identify trends and develop strategy based on insight analysis
from the field
• Develop and refine scientific communication and content for
expert-facing considerations
In the emerging world, generative
closes the feedback loop, speeds
time to content, helps SMEs
surface meaningful insights and
improves customer decisions

19. 19. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Augmented (Generative) Intelligence
in the Life Sciences:
“Sometimes the Hardest Thing
and the Right Thing Are the Same”
RIGHT
INTELLIGENCE
RIGHT MINDSET
RIGHT DATA
RIGHT EXPERTISE

20. 20. INIZIO ADVISORY | MEDICAL | MARCOMMS | ENGAGE | BIOTECH
Sometimes the
Hardest Thing
and the
Right Thing
are the Same