This document provides an overview of Industry 4.0 and how manufacturers can achieve digital transformation. It discusses what Industry 4.0 is, the current landscape of disconnected systems in manufacturing, and how solving problems and creating value through data insights. It also addresses common challenges of strategy, culture, leadership, focus and infrastructure for manufacturers. Finally, it outlines step-by-step recommendations for manufacturers to make Industry 4.0 a reality, including forming a digital team, learning from others, scaling initiatives, rethinking goals, and stimulating experiments.