Matt MacEwan -- Disruptive Diner: Nano Possibilities

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Presentation from 10/15/13 on Nano-Materials, highlighting those used in surgical meshes. Retectix founder Matt MacEwan explains how they make nano-materials and why they solve such a major problem for so many. Join OpenlyDisruptive.org for live access to more disruptive innovation events.

Technology Business

Matthew MacEwan, MD, PhD*
Founder / President
Property of Retectix, LLC. Confidential. © 2013.

OUTDATED TECHNOLOGY
Macroscopic

Nanoscopic

≠

Woven Mesh

Human Tissue

A BETTER SOLUTION?
Nanoscopic

Nanoscopic

? ≠

Synthetic, Non-Woven Material?

Human Tissue

APPLIED NANOTECHNOLOGY
Manufacturing Process:

Nanofiber Deposition
A.) Instrumentation:

Nanofiber Monolayers
B.) Collector:

C.) Resulting Fibers
Random

+

Planar Collector
Radial

Circular Collector +
Central Point Electrode

L

BIO-INSPIRED DESIGN
Nanoscopic

Nanoscopic

=

RETECTIX Nanofibers

Human Tissue

NOVEL BIOLOGICAL PROPERTIES
Random

Aligned

BENCHTOP TO BUSINESS

>$2 Billion Market / ASP $500
(1)  Millennium Research Report,
(2)  IMS 2010/2011

SCALING UP PRODUCTION
Nanofiber Deposition
A.) Instrumentation:

Nanofiber Monolayers
B.) Collector:

Layer Assembly

Surgical Mesh

• Proprietary methods
• Proprietary features

• Proprietary devices
• Proprietary uses
and applications

C.) Resulting Fibers
Random

+

Planar Collector
Radial

Circular Collector +
Central Point Electrode

• Proprietary method
• Proprietary equipment
• Proprietary process

• Proprietary patterns
• Proprietary designs
• Proprietary materials

INNOVATIVE SOLUTION

A new class of surgical mesh…

RAPID WOUND HEALING
Manufacturing Process:

Nanofiber Deposition

Novel Method
A.) Instrumentation:

Dura
Repaired
with

Unoperative Dura
Layer Assembly
Surgical Mesh
Cell Ingrowth
Regeneration
Radial
Nanofiber
Mesh
Nanomaterial
B.) Collector:
C.) Resulting Fibers
Nanofiber Monolayers

Dura
Re
Collag

Random

+

Planar Collector
Radial

Circular Collector +
Central Point Electrode

Animal Tissue

Unoperative Dura
Treated Collagen

(Cortical
view)

(Cortical
view)

Dura
Repaired
with

No Ingrowth
Radial
Nanofiber
Mesh

(Cortical
view)

(Cortical
view)

Dura
Repaired
with

Poor Healing
Collagen
Matrix

(Cortical
view)

(Cor

UNIQUE HANDLING & STRENGTH
Suture Pullout Strength (N)

18
16

14
12

10
8
6

4
2
0

DuraGen™

DuraMatrix™ DuraPatch™

DuraStar™
Cerafix™

Resistant to tears /suture pullout

POISED FOR GROWTH
Finished Device Manufacturer

Research & Development

Regulatory / Legal

OEM Manufacturing

BREAKING BOUNDARIES

Est. clinical release: Q2 2014

RETECTIX, LLC
4633 World Parkway Circle
St. Louis, MO 63134
info@retectix.com
www.retectix.com
Property of Retectix, LLC. Confidential. © 2013.

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