The document discusses the use of a 6.5F sheathless guiding catheter for transradial percutaneous coronary interventions (PCI) in patients with small radial arteries. The sheathless guiding catheter has an external diameter smaller than a 5F sheath but an internal diameter larger than a standard 6F guiding catheter. Several studies found that using the 6.5F sheathless guiding catheter for transradial PCI was feasible, effective, and safe for treating all lesion types and with various interventional techniques. The sheathless guiding catheter was particularly useful in cases where there was friction during intervention with smaller 4F-5F diagnostic catheters and sheaths or when a vessel was very small after use of a 6