This document describes the hospital course of a 57-year-old male with end-stage liver disease and a history of alcoholism. He was admitted with gastrointestinal bleeding from esophageal varices caused by cirrhosis. During his hospital stay, he developed worsening encephalopathy and required placement of a jejunostomy tube and later total parenteral nutrition (TPN) using Hepatamine. His condition stabilized and he was discharged on a soft diet with nutrition counseling and follow up.