A 32-year-old woman developed a liver abscess 44 days after undergoing a laparoscopic sleeve gastrectomy (LSG) for treatment of morbid obesity and diabetes. She initially recovered well from the LSG but later developed abdominal pain, vomiting, and fever. A CT scan revealed a 12x5 cm abscess in her liver. Drainage of the abscess yielded 400ml of pus. Antibiotic treatment and drainage of the abscess over subsequent days led to improvement of her symptoms and laboratory abnormalities. The abscess was considered a rare but possible complication of LSG due to the surgery being classified as clean-contaminated and the patient's comorbidities compromising her immune system.