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Lesson 5 - The role of Neurons in Memory formation




Friday, 13 April 2012
Last lesson......


  From which form of declarative memory is retrieval of
  information often more difficult? Why?
                                                          3 marks




Friday, 13 April 2012
Last lesson......


  From which form of declarative memory is retrieval of
  information often more difficult? Why?
                                                          3 marks


  Answer
  Retrieval of information is often more difficult from episodic
  memory.There memories are less well learned, and are more
  context dependent and state-dependent in nature.



Friday, 13 April 2012
Todays lesson............

 •Review the function of a neuron
 •Explain the role of the neuron in memory formation informed by the work of E.
 Richard Kandel!




Friday, 13 April 2012
Revision - The Neuron




Friday, 13 April 2012
Kandel found that any experience resulting in memory produces
 physical changes in the brain at the neuronal level, changes in
 structure and function of neurons.




Friday, 13 April 2012
Kandel’s Research on the role of neurons
   Eric Kandel studies the sea slug Aplysia for the following reasons:
     •Very simple nervous system
     •Only 20,000 neurons
     •Largest neurons in the world and can be seen with the naked eye




Friday, 13 April 2012
Kandel’s experiments
  Studied simple learning and remembering of the gill-
  withdrawal reflex of Aplysia

  Observed changes at the synapse (i.e. point of
  communication by adjacent neurons) in the structure and
  function of neurons in three ways:
  •Release extra neurotransmitter
  •Increase number of receptor sites
  •Growth of new synapses

  These changes are called collectively Long Term
  Potentiation

Friday, 13 April 2012
Long Term Potentiation




Friday, 13 April 2012
Friday, 13 April 2012
Friday, 13 April 2012

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Lesson 5 the role of the neuron in memory formation 2012 sh

  • 1. Lesson 5 - The role of Neurons in Memory formation Friday, 13 April 2012
  • 2. Last lesson...... From which form of declarative memory is retrieval of information often more difficult? Why? 3 marks Friday, 13 April 2012
  • 3. Last lesson...... From which form of declarative memory is retrieval of information often more difficult? Why? 3 marks Answer Retrieval of information is often more difficult from episodic memory.There memories are less well learned, and are more context dependent and state-dependent in nature. Friday, 13 April 2012
  • 4. Todays lesson............ •Review the function of a neuron •Explain the role of the neuron in memory formation informed by the work of E. Richard Kandel! Friday, 13 April 2012
  • 5. Revision - The Neuron Friday, 13 April 2012
  • 6. Kandel found that any experience resulting in memory produces physical changes in the brain at the neuronal level, changes in structure and function of neurons. Friday, 13 April 2012
  • 7. Kandel’s Research on the role of neurons Eric Kandel studies the sea slug Aplysia for the following reasons: •Very simple nervous system •Only 20,000 neurons •Largest neurons in the world and can be seen with the naked eye Friday, 13 April 2012
  • 8. Kandel’s experiments Studied simple learning and remembering of the gill- withdrawal reflex of Aplysia Observed changes at the synapse (i.e. point of communication by adjacent neurons) in the structure and function of neurons in three ways: •Release extra neurotransmitter •Increase number of receptor sites •Growth of new synapses These changes are called collectively Long Term Potentiation Friday, 13 April 2012