1. Demography is the study of population characteristics including size, composition, births, deaths, and migration. Census and vital statistics provide data on population attributes like age, sex, urban/rural distribution, and disease incidence and mortality rates.
2. Health indicators like crude birth rate, death rate, life expectancy, and infant mortality rate are calculated from vital statistics and measure the health status of a population. Rates and ratios reveal risks of diseases and deaths among groups.
3. Epidemiology studies disease distribution and determinants in populations to aid disease prevention and control. It examines historical disease patterns, diagnoses community health issues, evaluates health services, and estimates disease risks.
Predictive analysis WHO's life expectancy dataset using Tableau data visualis...Tarun Swarup
Performed predictive analysis on global Life expectancy dataset (WHO) to analyze the vital factors affecting human health and other societal risks demographically.
Designed a visual dashboard to identify intrinsic patterns in different factors and extract valuable insights to predict life expectancy accordingly.
▪ Infant Death Rate almost reduced by 40% in the last two decades.
▪ Overall adult mortality rate turned down by almost 17% in the previous years.
tHESE SLIDES ARE PREPAREED TO UNDERSTAND about DISPOSAL OF WASTE IN EASY WAY Important links- NOTES- https://mynursingstudents.blogspot.com/ youtube channel https://www.youtube.com/c/MYSTUDENTSU... CHANEL PLAYLIST- ANATOMY AND PHYSIOLOGY-https://www.youtube.com/playlist?list=PL93S13oM2gAPM3VTGVUXIeswKJ3XGaD2p COMMUNITY HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPyslPNdIJoVjiXEDTVEDzs CHILD HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gANcslmv0DXg6BWmWN359Gvg FIRST AID- https://www.youtube.com/playlist?list=PL93S13oM2gAMvGqeqH2ZTklzFAZhOrvgP HCM- https://www.youtube.com/playlist?list=PL93S13oM2gAM7mZ1vZhQBHWbdLnLb-cH9 FUNDAMENTALS OF NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPFxu78NDLpGPaxEmK1fTao COMMUNICABLE DISEASES- https://www.youtube.com/playlist?list=PL93S13oM2gAOWo4IwNjLU_LCuhRN0ZLeb ENVIRONMENTAL HEALTH- https://www.youtube.com/playlist?list=PL93S13oM2gAPkI6LvfS8Zu1nm6mZi9FK6 MSN- https://www.youtube.com/playlist?list=PL93S13oM2gAOdyoHnDLAoR_o8M6ccqYBm HINDI ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAN4L-FJ3s_IEXgZCijGUA1A ENGLISH ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAMYv2a1hFcq4W1nBjTnRkHP facebook profile- https://www.facebook.com/suresh.kr.lrhs/ FACEBOOK PAGE- https://www.facebook.com/My-Student-S... facebook group NURSING NOTES- https://www.facebook.com/groups/24139... FOR MAKING EASY NOTES YOU CAN ALSO VISIT MY BLOG – BLOGGER- https://mynursingstudents.blogspot.com/ Instagram- https://www.instagram.com/mystudentsu... Twitter- https://twitter.com/student_system?s=08 #PEM, #ASHA,#EPIDEMIOLOGY,#ICDS,#nurses,#ASSESSMENT, #APPEARENCE,#PULSE,#GRIMACE,#REFLEX,#RESPIRATION,#RESUSCITATION,#NEWBORN,#BABY,#VIRGINIA, #CHILD, #OXYGEN,#CYANOSIS,#OPTICNERVE, #SARACHNA,#MYSTUDENTSUPPORTSYSTEM, #rashes,#nursingclasses, #communityhealthnursing,#ANM, #GNM, #BSCNURING,#NURSINGSTUDENTS, #WHO,#NURSINGINSTITUTION,#COLLEGEOFNURSING,#nursingofficer,#COMMUNITYHEALTHOFFICE
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Predictive analysis WHO's life expectancy dataset using Tableau data visualis...Tarun Swarup
Performed predictive analysis on global Life expectancy dataset (WHO) to analyze the vital factors affecting human health and other societal risks demographically.
Designed a visual dashboard to identify intrinsic patterns in different factors and extract valuable insights to predict life expectancy accordingly.
▪ Infant Death Rate almost reduced by 40% in the last two decades.
▪ Overall adult mortality rate turned down by almost 17% in the previous years.
tHESE SLIDES ARE PREPAREED TO UNDERSTAND about DISPOSAL OF WASTE IN EASY WAY Important links- NOTES- https://mynursingstudents.blogspot.com/ youtube channel https://www.youtube.com/c/MYSTUDENTSU... CHANEL PLAYLIST- ANATOMY AND PHYSIOLOGY-https://www.youtube.com/playlist?list=PL93S13oM2gAPM3VTGVUXIeswKJ3XGaD2p COMMUNITY HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPyslPNdIJoVjiXEDTVEDzs CHILD HEALTH NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gANcslmv0DXg6BWmWN359Gvg FIRST AID- https://www.youtube.com/playlist?list=PL93S13oM2gAMvGqeqH2ZTklzFAZhOrvgP HCM- https://www.youtube.com/playlist?list=PL93S13oM2gAM7mZ1vZhQBHWbdLnLb-cH9 FUNDAMENTALS OF NURSING- https://www.youtube.com/playlist?list=PL93S13oM2gAPFxu78NDLpGPaxEmK1fTao COMMUNICABLE DISEASES- https://www.youtube.com/playlist?list=PL93S13oM2gAOWo4IwNjLU_LCuhRN0ZLeb ENVIRONMENTAL HEALTH- https://www.youtube.com/playlist?list=PL93S13oM2gAPkI6LvfS8Zu1nm6mZi9FK6 MSN- https://www.youtube.com/playlist?list=PL93S13oM2gAOdyoHnDLAoR_o8M6ccqYBm HINDI ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAN4L-FJ3s_IEXgZCijGUA1A ENGLISH ONLY- https://www.youtube.com/playlist?list=PL93S13oM2gAMYv2a1hFcq4W1nBjTnRkHP facebook profile- https://www.facebook.com/suresh.kr.lrhs/ FACEBOOK PAGE- https://www.facebook.com/My-Student-S... facebook group NURSING NOTES- https://www.facebook.com/groups/24139... FOR MAKING EASY NOTES YOU CAN ALSO VISIT MY BLOG – BLOGGER- https://mynursingstudents.blogspot.com/ Instagram- https://www.instagram.com/mystudentsu... Twitter- https://twitter.com/student_system?s=08 #PEM, #ASHA,#EPIDEMIOLOGY,#ICDS,#nurses,#ASSESSMENT, #APPEARENCE,#PULSE,#GRIMACE,#REFLEX,#RESPIRATION,#RESUSCITATION,#NEWBORN,#BABY,#VIRGINIA, #CHILD, #OXYGEN,#CYANOSIS,#OPTICNERVE, #SARACHNA,#MYSTUDENTSUPPORTSYSTEM, #rashes,#nursingclasses, #communityhealthnursing,#ANM, #GNM, #BSCNURING,#NURSINGSTUDENTS, #WHO,#NURSINGINSTITUTION,#COLLEGEOFNURSING,#nursingofficer,#COMMUNITYHEALTHOFFICE
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Best Ayurvedic medicine for Gas and IndigestionSwastikAyurveda
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. 1. Tools
1. Demography
Study of population size, composition and spatial distribution as affected by
births, deaths and migration.
a. Sources of Data
Census – complete enumeration of the population
2 Ways of Assigning People
1. De Jure – People were assigned to the place where assigned to the place
they usually live regardless of where they are at the time of census.
2. De Facto – People were assigned to the place where they are physically
present at are at the time of census regardless, of their usual place of
residence.
3. b. Population Size
c. Composition
Age Distribution
Sex Ratio
Population Pyramid
Median age – age below which 50% of the population falls and above which 50% of the
population falls. The lower the median age, the younger the population (high fertility, high
death rates).
Age – Dependency Ratio – used as an index of age-induced economic drain on human
resources
4. Other characteristics:
a. occupational groups
b. economic groups
c. educational attainment
d. ethnic group
d. Distribution
Urban-Rural – shows the proportion of people living in urban compared to
the rural areas
Crowding Index – indicates the ease by which a communicable disease can
be transmitted from 1 host to another susceptible host.
Population Density – determines congestion of the place
6. VITALSTATISTICS
Statistics refers to a systematic approach of
obtaining, organizing and analyzing numerical
facts so that conclusion may be drawn from
them.
Vital statistics refers to the systematic study of
vital events such as births, illnesses, marriages,
divorce, separation and deaths.
Statistics of disease(morbidity) and
death(mortality) indicate the state of health of
the community and the success or failure of the
health work.
Statistic on population and the characteristic
such as age and sex, distribution are obtained
from the National Statistics Office(NSO).
7. Use of Vital Statistics:
Indices of the health and illness status of a
community.
Serves as bases for planning, implementing,
monitoring and evaluating community health
nursing programs and services.
Sources of Data:
Population census
Registration of vital data
Health survey
Studies and researches
8. Rates and Ratios:
Rate- shows the relationship between a vital
event and those persons exposed to the
occurrence of said event, within a given area
and during a specifies unit of time.
Ratio- is used to describe the relationship
between two (2) numerical quantities or
measures of events without taking particular
considerations to the time or place.
Crude or General Rates- referred to the total
living population.
Specific Rate- specific population, class or
group.
9. Crude Birth Rate- measure of one characteristic of the natural growth or
increase of a population.
Total No. of live births registered in a given calendar year
CBR= ---------------------------------------------------------------- X 1,000
Estimated population as of July 1 of same year
Crude Death Rate- a measure of one mortality from all causes which may
result in a decrease of population
Total No. of live deaths registered in a given calendar year
CDR= ---------------------------------------------------------------------- X 1,000
Estimated population as of July 1 of same year
10. Infant Mortality Rate- measure the risk of dying during the first year of life.
Total No. of live death under 1 year of age registered in a given calendar year
IMR= -------------------------------------------------------------------------- X 1,000
Total No. of registered live births of same calendar year
Maternal Mortality Rate- measure the risk of dying from all causes related to
pregnancy, childbirth and puerperium.
Total No. deaths from maternal causes registered each year
MMR= ------------------------------------------------------------------------- X 1,000
Total No. of registered live births of same year
11. Infant Mortality Rate- measure the risk of dying during the first year of life.
Total No. of live death under 1 year of age registered in a given calendar year
IMR= -------------------------------------------------------------------------- X 1,000
Total No. of registered live births of same calendar year
Maternal Mortality Rate- measure the risk of dying from all causes related to
pregnancy, childbirth and puerperium.
Total No. deaths from maternal causes registered in a given year
MMR= -------------------------------------------------------------------------- X 1,000
Total No. of registered live births of same year
12. Specific Death Rate- describes more accurately the risk of exposure
of certain classes or groups to a particular disease.
Deaths in specific class/group registered in a given calendar year
Specific Death Rate= ------------------------------------------------------- X 100,000
Estimated population as of July 1 in same specified class/group of said year
13. Adjusted or Standardized Rate
Methods:
By applying observed specific rates to some standard population
By applying specific rates of standard population to corresponding classes or
groups of the local population
Case Fatality Ratio- index of a killing power of disease and is influenced by
incomplete reporting and poor morbidity data.
No. of registered deaths from a specific disease for a given year
PM= -------------------------------------------------------------- X 100
No. of registered cases from specific disease in same year
14. Presentation of Data
Line or curved graphs- shows peaks, valleys and seasonal trends
Bar graphs- represents or expresses a quantity in terms of rates or
percentages of a particular observation
Area Diagram- (Pie Charts)- shows the relative importance of parts
to the whole.
Functions of the Nurse
Collects data
Tabulates data
analyzes and interprets data
Evaluates data
Recommends redirection and/ or strengthening of specific areas
of health programs as needed.
15. Philippine Health Situation
Population
Chart and table of Philippines population from 1950 to 2020. United Nations
projections are also included through the year 2100.
The current population of Philippines in 2020 is 109,581,078, a 1.35% increase
from 2019.
The population of Philippines in 2019 was 108,116,615, a 1.37% increase from
2018.
The population of Philippines in 2018 was 106,651,394, a 1.41% increase from
2017.
The population of Philippines in 2017 was 105,172,925, a 1.46% increase from
2016.
16. Life Expectancy
Chart and table of Philippines life expectancy from 1950 to 2020.
United Nations projections are also included through the year
2100.
The current life expectancy for Philippines in 2020 is 71.28 years, a
0.18% increase from 2019.
The life expectancy for Philippines in 2019 was 71.16 years, a
0.18% increase from 2018.
The life expectancy for Philippines in 2018 was 71.03 years, a
0.23% increase from 2017.
The life expectancy for Philippines in 2017 was 70.87 years, a
0.23% increase from 2016.
17. Crude Birth Rate
Chart and table of the Philippines birth rate from 1950 to
2020. United Nations projections are also included through
the year 2100.
The current birth rate for Philippines in 2020 is 20.177
births per 1000 people, a 0.98% decline from 2019.
The birth rate for Philippines in 2019 was 20.377 births per
1000 people, a 0.97% decline from 2018.
The birth rate for Philippines in 2018 was 20.576 births per
1000 people, a 3.31% decline from 2017.
The birth rate for Philippines in 2017 was 21.280 births per
1000 people, a 3.2% decline from 2016.
18. Infant Mortality Rate
Chart and table of the Philippines infant mortality rate from
1950 to 2020. United Nations projections are also included
through the year 2100.
The current infant mortality rate for Philippines in 2020 is
18.815 deaths per 1000 live births, a 2.2% decline from 2019.
The infant mortality rate for Philippines in 2019 was 19.239
deaths per 1000 live births, a 2.16% decline from 2018.
The infant mortality rate for Philippines in 2018 was 19.663
deaths per 1000 live births, a 3.96% decline from 2017.
The infant mortality rate for Philippines in 2017 was 20.474
deaths per 1000 live births, a 3.81% decline from 2016.
19.
20.
21.
22. EPIDEMIOLOGY
Epidemiology is the study of occurrences and distribution of diseases as well as
the distribution and determinants of health states or events in specified
population, and the application of this study to the control of health problems.
This emphasizes that epidemiologist are concerned not only with deaths, illness
and disability, but also with more positive health states and with the means to
improve health.
Two main areas of investigation are concerned in the definition, the study of the
distribution of disease and the search for the determinants (causes) of the
disease and its observed distributions. The first area describes the distribution of
health status in terms of age, gender, race, geography, time and so on might be
considered in an expansion of the discipline of demography to health and
diseases. The second area involves explanations of the patterns of disease
contribution in terms of casual factors.
Epidemiology , therefore is the backbone of the prevention disease.
23. Uses of Epidemiology:
According to Morris, epidemiology is used to:
Study the history of the health population and the rise and fall of diseases
and changes in their character.
Diagnose the health of the community and the condition of people to
measure the distribution and dimension of illness in terms of incidence,
prevalence, disability and mortality, to set health problems in perspective
and to define their relative importance and to identify groups needing
special attention.
Study the work of health services with the view of improving them.
Operational research shows how the community expectations can result in
the actual provisions of service .
Estimate the risk of disease, accidents , defects and the changes of avoiding
them.
Identify syndromes by describing the distribution and association of clinical
phenomena in the population.
Complete the clinical picture of chronic disease and describe their natural
history.
Search for causes of health and disease by comparing the experience of
groups that are clearly defined by their composition, inheritance,
experience, behavior and environments.
24. Figure 4- The Epidemiology Triangle
HOST
AGENT
ENVIRONMENT
25. The Epidemiology Triangle
The Epidemiology Triangle consists of three component –
host, environment and agent. The model implies that each
must be analyzed and understood for comprehensions and
prediction of patterns of a disease. A change in any of the
component will alter an existing equilibrium to increase or
decrease of the disease.
The host is any organism that harbors and provides
nourishment for another organism.
Agent is the intrinsic property of microorganism to survive
and multiply in the environment to produce disease.
Environment is the sum total of all external condition and
influences that effects the development of an organism
which can be biological, social and physical.
26. The three component of the environment:
Physical Environment – composed of the inanimate
surroundings such as the geophysical conditions of
the climate.
Biological environment makes up the living things
around us such as plants and animal life.
Socio-economic environment which may be in the
form of level of economic development of the
community, presence of social disruptions and the
like.
27. Approach to Disease and its Determinants
The present epidemiology approach is based on
the interaction of the host, the causative agent,
and the environment.
The presence of infectious materials varies with
the duration and the extent of its excretion from
an infected person the climactic conditions
affecting survival of the agent, route of entry into
the host and the existence of alternative
reservoirs or host of the agent.
28. Classifications of Agents, Hosts and Environmental Factors which determine the
occurrence of Disease in Human Population
1.Agents of Disease
a. Nutritive elements
b. Chemical agents
c. Physical agents
d. Infectious agents
29. 2. Host factors ( Intrinsic Factors) – influences
exposure, susceptibility or response to agents.
a.Genetic
b. Age
c. Sex
d. Ethnic group
e. Physiologic
f. Immunologic Experience
g. Inter- current or pre-existing disease
h. Human behavior
30. 3. Environmental factors (Extrinsic factors)
– influences existence of the agent,
exposure, or susceptibility to agent.
A. Physical environment
B. Biologic environment
C. Socio-economic environment
31. Disease Distribution
The methods and technique of epidemiology are
desired to detect the cause of a disease in
relation to the characteristics of the person who
ahs it or to a factor present in his environment.
Since neither population and environment of
different times or places are similar, these
characteristics and factors are called
epidemiology variables.
32. Time refers to both the period during which the cases of the
disease being studied were exposed to the source of infection
and the period during which the illness occurred.
Persons refers to the characteristics of the individual who were
exposed and who contacted the infection or the disease in
question.
Place refers to the features, factors or conditions which existed
in or described the environment in which the disease
occurred.
33. Patterns of Occurrence and
Distribution
The variables of disease as to person, time, and place are
reflected in distinct patterns of occurrence and distribution in
each community.
1.Sporadic occurrence is the intermittent occurrence of e few
isolated and unrelated cases in each locality. The cases are few
and scattered, so that there is no apparent relationship
between them, and they occur on and off, intermittently,
through a period.
2.Endemic occurrence is the continuous occurrence throughout a
period, of the usual number of cases in each locality. The
disease is therefore always occurring in the locality and the
level of occurrence is less or more constant through a period.
34. 3.Epidemic occurrence is of unusually large number
of cases in a relatively short period of time.
There is no disproportionate relationship
between the number of cases and the period of
occurrence, the more acute is the disproportion,
the more urgent and serious is the problem.
4. Pandemic is the simultaneous occurrence of
epidemic of the same disease in several
countries.
35. Epidemics
Factor’s Contributory to Epidemic Occurrence:
Agent Factor – the result of the introduction of new
disease agents in the population.
Host Factors – are related to lower resistance as a result
of exposure to the elements during floods or other disaster,
to relaxed supervision of water and milk supply or sewage
disposal, or to changed habit of eating.
Environmental factors – changes in the physical
environment: temperature, humidity, rainfall may directly
or indirectly influence equilibrium of agent and host.
36. Outline of Plan for Epidemiological Investigation
1. Establish fact of presence of epidemic
2. Establish time and space relationship
of the disease
3. Establish time and space relationship
of the disease
4. Correlation of all data
37. Epidemiology and Surveillance Units
Epidemiology and Surveillance Units have been established
in regional and some local office as support to the public
health system. As an epidemiologic information service, the
unit is mainly responsible for providing timely and accurate
information on diseases in the locality.
Among its responsibility includes:
Surveillance of infectious diseases with outbreak potential
Assisting local government units in investigation of outbreak
and their control
Developing information package on public health.
Providing technical assistance related to epidemiology.
38. Public Health Surveillance
Public Health Surveillance is an on-going systematic
collection, analysis, interpretation and
dissemination of health data.
Surveillance system is often considered in
information loops or cycles involving health care
providers, public health agencies and the public.
39. ROLEOFTHENURSEIN SURVEILLANCE
One of the areas where public health nurse function as
researcher is disease surveillance.
Surveillance is a continuous collection and analysis of data of
cases and death.
The objectives of surveillance are:
1.To measure the magnitude of the problem.
2. To measure the effect of the control program.
40. The National Epidemic Sentinel Surveillance
System (NESSS) and its Role
National Epidemic Sentinel Surveillance System
is a hospital-based information system that
monitors the occurrence of infectious diseases
with outbreak potential. It also serves as a
supplemental information system of the
Development of Health.
41. Objectives:
To provide early warning on occurrence of outbreaks
To provide program managers, policy makers, and public
administrators, rapid accurate and timely information so
that inventive and control measures can be instituted.
The NESSS Data shows:
Trends of cases across time
Demographic characteristics of cases
Estimates of case fatality ratio
Clustering of cases in geographical area
Information to formulate hypothesis for disease causation
42. Disease Under Surveillance (NESSS)
Laboratory Diagnosed
Cholera
Hepatitis A
Hepatitis B
Malaria
Typhoid Fever
44. Under Surveillance System:
Acute Flaccid paralysis
Measles
Maternal and neonatal tetanus
Paralytic shellfish poisoning
fireworks and related injury
HIV / AIDS
45. Importance of Outbreak Investigation:
Control and prevention measure
Severity and risk to others
Research opportunities
Public, political or legal concerns
Training
Sources:
Surveillance data
Medical practitioner
Affected persons / group
Concerned citizen
Media
46. Steps in Outbreak Investigation:
Step 1 – Prepare for field work
Investigation
Scientific knowledge
Supplies / equipment
Administration
Administrative procedures like travel documents, allowance
Consultation
Know expected role
Local contact person
47. Step 2 – Establish the existence or an outbreak
Cluster – is an aggregation of cases in each are over a
particular period without regards to whether the number of
cases is more than the expected.
Outbreak or an epidemic – is the occurrence of more cases of
disease rather than expected in each area or among a specific
group of people over a particular period.
Compare the current number of cases with the numbers of
cases from comparable period during the previous years.
Surveillance records
Hospital records, registries, mortality statistics
Data from neighboring areas
Community survey
48. Step 3 – Verify diagnosis
Ensure proper diagnosis of reported cases
Rule out laboratory error as basis for the
increase in diagnosed cases
Reviews clinical findings
Review laboratory results
Summarize clinical findings with the frequency
distribution
Visit patients
49. Step 4 – Define and Identify cases
A. Establish a case definition
Standards set of criteria for the health condition;
Clinical criteria ( signs and symptoms)
Restrictions by time, place, persons
Apply without bias
Note – exposure or risk factor is not included in the case
definition
B. Identify and count cases
Identify information – name, address, contact number
Demographic information – age, sex, race and occupation
Clinical information – death of onset, hospitalization,
death
Risk factors information – food or water sources, toilet
facility
Reporter information
50. Step 5 – Perform descriptive
epidemiology
Describe and orient the data in terms of time, place and
person
Characterized by time
Characterized by place
Characterized by persons
51. Step 6 – Developing Hypothesis
Consider
Source of agent
Mode of transmission
Vectors of transmission
Risk Factors
Hypothesis should be testable
52. Step 7 – Evaluate hypothesis by:
Comparing with established facts
Use of analytical epidemiology
Case control studies
Retrospective control studies
53. Step 8 – Refine hypothesis and execute
additional studies because:
Unrevealing analytical studies = poor hypothesis
May need more specific exposure histories
May need mire specific control group
Step 9 – Implement control and prevention
measures
Prevent additional cases
Prevent outbreaks in the future
54. Step 10 – Communicate findings
Through;
Writing and disseminating full report
Meetings and discussions
Local and mass media
Step 11 - Follow- up Recommendations
What activities have been undertaken?
If health status has improved
If health problems has been reduced
55. Function of the Epidemiology Nurse:
Implement public health surveillance
Monitor local health personnel conducting disease
surveillance
Conduct and / or assist other health personnel in
outbreak investigation
Assist in the conduct of rapid surveys and
surveillance during disasters
Assist in the conduct of surveys, program evaluation,
and other epidemiologic studies.
Assist in the conduct of training course in
epidemiology
Assist the epidemiologist in preparing the annual
report and financial plan.
Responsible for inventory and maintenance of
epidemiology and surveillance unit (ESU) equipment
56. Specific Role during Epidemiological
Investigations:
Maintains surveillance of the occurrence of
notifiable disease.
Coordinates with other members of the health
team during the disease outbreak
Participates in case findings and collection of
laboratory specimens
Isolates cases of communicable disease.
Renders nursing care, teaches and supervises
giving care.
Performs and teach household members
method, concurrent and terminal disinfection.
57. Gives health teachings to prevent further spreads of
disease to individual and families.
Follow up cases and contacts
Organizes, coordinates and conducts community
health education campaign / meetings.
Refers cases when necessary
Coordinates with other concerned community
agencies.
Accomplishes and keeps records and reports and
submits to proper office / agency.