SlideShare a Scribd company logo
به نام کسی که اون بالاست و همه رو دوس داره به نام کسی که اون بالاست و همه رو دوس داره به نام کسی که اون بالاست و همه رو دوس داره
Zeffix® Lamivudine (3TC) Class:NRTI Structre & SAR: 2',3'-dideoxy-3'-thiacytidine
Trade Names & dosage forms  zeffix® Epivir-HBV® Epivir® Heptovir® (Canada) combivir® trizivir® - FcTab.     100 mg - Oral solution  5 mg/ml - Tab. 150 , 300  mg- Solution, oral 10 mg/mL
Trade Names & dosage forms  Biovudine ®  -Scored F.C. Tab.  100,150 mg  Exivudin® -Tab.  150 mg
Indications and Dosage Zeffix®
Absorption Distribution Metabolism Elimination Pharmacokinetics Zeffix®
Contraindications & precautions Hypersensitivity to drug Pancreatitis Impaired renal function Zeffix® Lactation Obesity  Pregnancy Pregnancy & lactation Category C
Interactions tmp-smx zidovudone   Interferon Ribavirin Zalcitabine Zeffix®
AdverseReactions CNS GI pancreatitis LabTests ANC, platelets Metabolic:  lactic acidosis Zeffix® Overdosage
     PatientInformation not a cure lactic acidosis Breast feedingh children & pancreatitis Zeffix®
Refrences: Applied Therapeutics - The Clinical Use Of Drugs,   Mary annekoda-kimble [et al.], 9th Ed.( 2009), p:69-4 , 69-4, 73-26 AHFS drug information essentials (2006-7) Gerald K. McEvoy P:8.18.08.20 Textbook of therapeutics – drug and disease management,   Richard A. Helms [et al.], 8th ed. P: 1339  Drug information handbook, Charles F. lacy[et al.] 14th ed.(2006)P:967 Physician Drug Handbook, Michael F. beer, 12th ed.(2008) P:688 Drug interaction facts , David s. tatro ,12th ed. (2006) P:855 www.drugs.com/ppa/lamivudine-3tc.html
الا ای طوطی گویای اسرار     مبادا خالیت شکر ز منقار شنیدین که شاعر میگه:     روزی خواهم آمد و پیامی خواهم آورد         خواهم آمد گل یاسی به گدا خواهم داد               خواهم آمد سر هر دیواری میخکی خواهم کاشت...

More Related Content

What's hot

Pharmacology of Ondansetron (Zofran)
Pharmacology of Ondansetron (Zofran)Pharmacology of Ondansetron (Zofran)
Pharmacology of Ondansetron (Zofran)
Dana Luery
 
Antiscabies agents
Antiscabies agentsAntiscabies agents
Antiscabies agents
RijoLijo
 
Drug presentation on diazepam
Drug presentation on diazepam Drug presentation on diazepam
Drug presentation on diazepam
SUJAYS22
 
Nifedipine (procardia)
Nifedipine (procardia)Nifedipine (procardia)
Nifedipine (procardia)
brhodes4
 
Aspirin (drug presentation) for medical students .
Aspirin (drug presentation) for medical students .Aspirin (drug presentation) for medical students .
Aspirin (drug presentation) for medical students .
NehaNupur8
 
Voveran (Generic Diclofenac Sodium Tablets)
Voveran  (Generic Diclofenac Sodium Tablets)Voveran  (Generic Diclofenac Sodium Tablets)
Voveran (Generic Diclofenac Sodium Tablets)
The Swiss Pharmacy
 
Gentamicin
GentamicinGentamicin
Presentation On ‘‘Esomeprazole’’
Presentation On ‘‘Esomeprazole’’Presentation On ‘‘Esomeprazole’’
Presentation On ‘‘Esomeprazole’’
Anm Sharif
 
Furosemide DRUG PROFILE
Furosemide DRUG PROFILEFurosemide DRUG PROFILE
Furosemide DRUG PROFILE
Irfan Ahmed
 
Pantoprazole
PantoprazolePantoprazole
Ceftriaxone
CeftriaxoneCeftriaxone
Ceftriaxone
aleeshba usman
 
Metronidazole.ppt
Metronidazole.pptMetronidazole.ppt
Metronidazole.ppt
Dr Ndayisaba Corneille
 
Diuretics II
Diuretics IIDiuretics II
Diuretics II
Pravin Prasad
 
Bronchodilators
BronchodilatorsBronchodilators
Bronchodilators
bhavesh vaghela (M.Pharm)
 
Tramadol
TramadolTramadol
Nasogastric Tube.pptx
Nasogastric Tube.pptxNasogastric Tube.pptx
Nasogastric Tube.pptx
AbrahamSheriff1
 
Theophylline-CNS stimulant
Theophylline-CNS stimulantTheophylline-CNS stimulant
Theophylline-CNS stimulant
Mosese HULKSTAH Tuapati JNR
 
Hematinics
HematinicsHematinics
Ciprofloxacin Antibiotic
Ciprofloxacin AntibioticCiprofloxacin Antibiotic
Ciprofloxacin Antibiotic
Mosese HULKSTAH Tuapati JNR
 
Calcium gluconate
Calcium gluconateCalcium gluconate
Calcium gluconate
Anubliss
 

What's hot (20)

Pharmacology of Ondansetron (Zofran)
Pharmacology of Ondansetron (Zofran)Pharmacology of Ondansetron (Zofran)
Pharmacology of Ondansetron (Zofran)
 
Antiscabies agents
Antiscabies agentsAntiscabies agents
Antiscabies agents
 
Drug presentation on diazepam
Drug presentation on diazepam Drug presentation on diazepam
Drug presentation on diazepam
 
Nifedipine (procardia)
Nifedipine (procardia)Nifedipine (procardia)
Nifedipine (procardia)
 
Aspirin (drug presentation) for medical students .
Aspirin (drug presentation) for medical students .Aspirin (drug presentation) for medical students .
Aspirin (drug presentation) for medical students .
 
Voveran (Generic Diclofenac Sodium Tablets)
Voveran  (Generic Diclofenac Sodium Tablets)Voveran  (Generic Diclofenac Sodium Tablets)
Voveran (Generic Diclofenac Sodium Tablets)
 
Gentamicin
GentamicinGentamicin
Gentamicin
 
Presentation On ‘‘Esomeprazole’’
Presentation On ‘‘Esomeprazole’’Presentation On ‘‘Esomeprazole’’
Presentation On ‘‘Esomeprazole’’
 
Furosemide DRUG PROFILE
Furosemide DRUG PROFILEFurosemide DRUG PROFILE
Furosemide DRUG PROFILE
 
Pantoprazole
PantoprazolePantoprazole
Pantoprazole
 
Ceftriaxone
CeftriaxoneCeftriaxone
Ceftriaxone
 
Metronidazole.ppt
Metronidazole.pptMetronidazole.ppt
Metronidazole.ppt
 
Diuretics II
Diuretics IIDiuretics II
Diuretics II
 
Bronchodilators
BronchodilatorsBronchodilators
Bronchodilators
 
Tramadol
TramadolTramadol
Tramadol
 
Nasogastric Tube.pptx
Nasogastric Tube.pptxNasogastric Tube.pptx
Nasogastric Tube.pptx
 
Theophylline-CNS stimulant
Theophylline-CNS stimulantTheophylline-CNS stimulant
Theophylline-CNS stimulant
 
Hematinics
HematinicsHematinics
Hematinics
 
Ciprofloxacin Antibiotic
Ciprofloxacin AntibioticCiprofloxacin Antibiotic
Ciprofloxacin Antibiotic
 
Calcium gluconate
Calcium gluconateCalcium gluconate
Calcium gluconate
 

lamivudine

  • 1. به نام کسی که اون بالاست و همه رو دوس داره به نام کسی که اون بالاست و همه رو دوس داره به نام کسی که اون بالاست و همه رو دوس داره
  • 2. Zeffix® Lamivudine (3TC) Class:NRTI Structre & SAR: 2',3'-dideoxy-3'-thiacytidine
  • 3. Trade Names & dosage forms zeffix® Epivir-HBV® Epivir® Heptovir® (Canada) combivir® trizivir® - FcTab. 100 mg - Oral solution 5 mg/ml - Tab. 150 , 300 mg- Solution, oral 10 mg/mL
  • 4. Trade Names & dosage forms Biovudine ® -Scored F.C. Tab. 100,150 mg Exivudin® -Tab. 150 mg
  • 6. Absorption Distribution Metabolism Elimination Pharmacokinetics Zeffix®
  • 7. Contraindications & precautions Hypersensitivity to drug Pancreatitis Impaired renal function Zeffix® Lactation Obesity Pregnancy Pregnancy & lactation Category C
  • 8. Interactions tmp-smx zidovudone Interferon Ribavirin Zalcitabine Zeffix®
  • 9. AdverseReactions CNS GI pancreatitis LabTests ANC, platelets Metabolic: lactic acidosis Zeffix® Overdosage
  • 10. PatientInformation not a cure lactic acidosis Breast feedingh children & pancreatitis Zeffix®
  • 11.
  • 12. Refrences: Applied Therapeutics - The Clinical Use Of Drugs, Mary annekoda-kimble [et al.], 9th Ed.( 2009), p:69-4 , 69-4, 73-26 AHFS drug information essentials (2006-7) Gerald K. McEvoy P:8.18.08.20 Textbook of therapeutics – drug and disease management, Richard A. Helms [et al.], 8th ed. P: 1339 Drug information handbook, Charles F. lacy[et al.] 14th ed.(2006)P:967 Physician Drug Handbook, Michael F. beer, 12th ed.(2008) P:688 Drug interaction facts , David s. tatro ,12th ed. (2006) P:855 www.drugs.com/ppa/lamivudine-3tc.html
  • 13. الا ای طوطی گویای اسرار مبادا خالیت شکر ز منقار شنیدین که شاعر میگه: روزی خواهم آمد و پیامی خواهم آورد خواهم آمد گل یاسی به گدا خواهم داد خواهم آمد سر هر دیواری میخکی خواهم کاشت...