Durable medical equipment (DME) provides therapeutic benefits for long-term home use. The Centers for Medicare and Medicaid Services uses HCPCS codes and modifiers to identify DME parameters and make codes valid for claims processing. Modifiers are divided into categories like routinely purchased items, capped rental items, oxygen equipment, prosthetics, and more. They provide essential details about equipment usage, replacements, and prescriptions to facilitate reimbursement.