Global Medical Cures™ | Cirrhosis of the Liver
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices
AIP is an enzyme which is width sprid through the body tissue has an important role in alkaline medium for the conversion of phospate from one substance. to remove phosphate group.
Global Medical Cures™ | Cirrhosis of the Liver
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices
AIP is an enzyme which is width sprid through the body tissue has an important role in alkaline medium for the conversion of phospate from one substance. to remove phosphate group.
Fatty Liver Fix & Rapid Fat Loss FrameworkAjay Agnihotri
The Rapid Fat Loss Framework Forces Your Body To Lose Weight Without Hunger and Stress Imagine eating much less and feeling happy.You can experience both if you choose to try the Rapid Fat Loss Framework.
It might sound impossible, but we have developed a 10-day system that nourishes your body in a way that silences the hunger signals that force you to eat.You're encouraged to eat a lot on the Rapid Fat Loss Framework.
In this article of liver cleansing, we'll show how to cleanse your liver naturally by following a diet routine that consists of liver cleansing foods. For more https://www.livealittlelonger.com/liver-cleansing/
In this article of liver cleansing, we'll show how to cleanse your liver naturally by following a diet routine that consists of liver cleansing foods. For More https://www.livealittlelonger.com/liver-cleansing/
In this PDF of liver cleansing, we'll show how to cleanse your liver naturally by following a diet routine that consists of liver cleansing foods. For More https://www.livealittlelonger.com/liver-cleansing/
Like diabetes, Fatty liver disease is also considered a Silent Killer disease because people don’t feel any symptoms in the initial stage of fatty liver disease.
It slowly comes into your body and causes chronic liver disease.
The severity of the fatty liver disease depends on fatty liver grades. Your liver condition will become more vulnerable if fatty liver grades get increase.
Fatty liver disease is a metabolic disease where fat gets stored in your hepatocytes or liver cells that, cause inflammation.
There are two main types of fatty liver disease – alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD).
Fatty liver disease is generally graded based on the amount of fat stored and the degree of liver damage. This is called Fatty Liver Grades.
Simply, this fatty liver grade represents stages of fatty liver. There are four grades of fatty liver – Grade 1, Grade 2, Grade 3 and Grade 4.
Fatty liver disease is a silent disease; it comes with no signs or symptoms.
NAFLD (non-inflammatory or Grade 1 fatty liver) is asymptomatic, meaning you don’t feel any symptoms.
Still, you may have fatigue, thirst, anxiety, upper abdominal pain, bloating or discomfort, etc. These are the most common symptoms of NAFLD.
As the disease progresses, symptoms start appearing, usually in advance grading of fatty liver disease such as NASH (inflammatory fatty liver)
If left untreated, you may have a more severe liver condition that gets more complicated.
Although the exact cause of fatty liver is still unclear, but there are certain possible reasons to cause fatty liver.
A bad lifestyle is the most significant risk factor for developing NAFLD (Non-alcoholic fatty liver disease).
The good news is that you can reverse your fatty liver disease and even cure it.
If you get diagnosed early, it can be treated because some fatty liver grades are reversible, such as grade 1, grade 2 and grade 3.
But if you get liver cirrhosis or grade 4 fatty liver, that is irreversible. At this stage, your liver cells cannot reduce fat and can’t return to a healthy liver.
This post will discuss fatty liver grades, types, causes, pathology, symptoms, complications, diagnostic tests and treatment.
Effective treatment for obesity in Mindheal Homeopathy clinic ,Chembur, Mum...Shewta shetty
"Obesity- Obesity refers to excessive fat accumulation in the body. Mindheal homeopathy induces the patient to make a dietary and lifestyle changes to control obesity"/>
The human body is made up, among others, of billions of fat cells. These fat cells are in a way important for our body’s functioning however too much body fat can give way to many health problems. The methods on how to lose stomach fat provided in this report are your first steps towards a fit physique and healthier lifestyle.
Effective treatment for obesity in Mindheal Homeopathy clinic ,Chembur, Mum...Shewta shetty
"Obesity- Obesity refers to excessive fat accumulation in the body. Mindheal homeopathy induces the patient to make a dietary and lifestyle changes to control obesity"/>
What is liver Cirrhosis?
Liver cirrhosis is a devastating condition affecting thousands of people every year. It is a condition that results from chronic alcohol consumption and has many other reasons behind it. Liver cirrhosis is an end-stage liver disease characterized by the deep scarring of the liver tissue. In this condition, the healthy liver tissue is replaced with damaged tissue leaving a permanent scar in the liver. The damaged liver tissue may keep your liver from functioning properly.
Also, various liver diseases and conditions injure the healthy liver cells and result in hepatocyte cell death and inflammation. This is followed by cell repair and, finally, tissue scarring due to the repair process.
The damaged/scarred tissue inhibits the blood flow towards the liver. It hampers its ability to digest and process the various nutrients, medications, hormones, and natural toxins (poisons) that we consume in our day to day life. The liver also plays a vital role in producing proteins and other substances, which may be hampered due to liver disease like liver cirrhosis. Liver Cirrhosis treatment, when not undertaken at the right time, can become a life-threatening disorder.
Liver Cirrhosis is one of the deadliest complications, which is caused by liver diseases. Irreversible scarring and loss of liver cells are involved in Liver Cirrhosis. The major causes of Liver Cirrhosis are consumption of alcohol and Hepatitis B and Hepatitis C as well. There can be other causes and diseases which may lead to cirrhosis of the liver.
Liver Cirrhosis
Symptoms Of Liver Cirrhosis
People in the initial stages may go through a feeling of weakness, and there might be a sudden loss in weight without any particular reason. In the later stages, the patients may have jaundice. The following are the symptoms that a person suffering from Liver Cirrhosis may have in different parts of the body:
Abdomen: There may be severe pain in the abdomen region, and veins around the belly button may get enlarged.
Gastrointestinal: There may be bleeding occurrences, and fluids may start to accumulate in the abdomen. There can be an excessive formation of gas. The Excretion of dark stool is also a visible symptom.
Skin: Skin may turn yellow along with swelling of blood vessels that can be visible through the skin.
Mind: It not only affects the body but the mind as well; you may go through nausea and may feel a sense of confusion all the time.
Whole Body: You may gain or lose weight unintentionally without doing anything about it. There can be breast enlargement, dark urine, breathlessness, itching, vomiting of blood, etc
Other Services
Endoscopy
Colonoscopy
ERCP
Sigmoidoscopy
Pancreatic Disease
Liver Cirrhosis Treatment in Chandigarh
How can I prevent cirrhosis of the liver?
Liver cirrhosis treatment involves many lifestyle and dietary modifications which needs to be followed along with the medical treatment. Some of the lifestyle modifications for liver cirrhosis treat
Fatty Liver Fix & Rapid Fat Loss FrameworkAjay Agnihotri
The Rapid Fat Loss Framework Forces Your Body To Lose Weight Without Hunger and Stress Imagine eating much less and feeling happy.You can experience both if you choose to try the Rapid Fat Loss Framework.
It might sound impossible, but we have developed a 10-day system that nourishes your body in a way that silences the hunger signals that force you to eat.You're encouraged to eat a lot on the Rapid Fat Loss Framework.
In this article of liver cleansing, we'll show how to cleanse your liver naturally by following a diet routine that consists of liver cleansing foods. For more https://www.livealittlelonger.com/liver-cleansing/
In this article of liver cleansing, we'll show how to cleanse your liver naturally by following a diet routine that consists of liver cleansing foods. For More https://www.livealittlelonger.com/liver-cleansing/
In this PDF of liver cleansing, we'll show how to cleanse your liver naturally by following a diet routine that consists of liver cleansing foods. For More https://www.livealittlelonger.com/liver-cleansing/
Like diabetes, Fatty liver disease is also considered a Silent Killer disease because people don’t feel any symptoms in the initial stage of fatty liver disease.
It slowly comes into your body and causes chronic liver disease.
The severity of the fatty liver disease depends on fatty liver grades. Your liver condition will become more vulnerable if fatty liver grades get increase.
Fatty liver disease is a metabolic disease where fat gets stored in your hepatocytes or liver cells that, cause inflammation.
There are two main types of fatty liver disease – alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD).
Fatty liver disease is generally graded based on the amount of fat stored and the degree of liver damage. This is called Fatty Liver Grades.
Simply, this fatty liver grade represents stages of fatty liver. There are four grades of fatty liver – Grade 1, Grade 2, Grade 3 and Grade 4.
Fatty liver disease is a silent disease; it comes with no signs or symptoms.
NAFLD (non-inflammatory or Grade 1 fatty liver) is asymptomatic, meaning you don’t feel any symptoms.
Still, you may have fatigue, thirst, anxiety, upper abdominal pain, bloating or discomfort, etc. These are the most common symptoms of NAFLD.
As the disease progresses, symptoms start appearing, usually in advance grading of fatty liver disease such as NASH (inflammatory fatty liver)
If left untreated, you may have a more severe liver condition that gets more complicated.
Although the exact cause of fatty liver is still unclear, but there are certain possible reasons to cause fatty liver.
A bad lifestyle is the most significant risk factor for developing NAFLD (Non-alcoholic fatty liver disease).
The good news is that you can reverse your fatty liver disease and even cure it.
If you get diagnosed early, it can be treated because some fatty liver grades are reversible, such as grade 1, grade 2 and grade 3.
But if you get liver cirrhosis or grade 4 fatty liver, that is irreversible. At this stage, your liver cells cannot reduce fat and can’t return to a healthy liver.
This post will discuss fatty liver grades, types, causes, pathology, symptoms, complications, diagnostic tests and treatment.
Effective treatment for obesity in Mindheal Homeopathy clinic ,Chembur, Mum...Shewta shetty
"Obesity- Obesity refers to excessive fat accumulation in the body. Mindheal homeopathy induces the patient to make a dietary and lifestyle changes to control obesity"/>
The human body is made up, among others, of billions of fat cells. These fat cells are in a way important for our body’s functioning however too much body fat can give way to many health problems. The methods on how to lose stomach fat provided in this report are your first steps towards a fit physique and healthier lifestyle.
Effective treatment for obesity in Mindheal Homeopathy clinic ,Chembur, Mum...Shewta shetty
"Obesity- Obesity refers to excessive fat accumulation in the body. Mindheal homeopathy induces the patient to make a dietary and lifestyle changes to control obesity"/>
What is liver Cirrhosis?
Liver cirrhosis is a devastating condition affecting thousands of people every year. It is a condition that results from chronic alcohol consumption and has many other reasons behind it. Liver cirrhosis is an end-stage liver disease characterized by the deep scarring of the liver tissue. In this condition, the healthy liver tissue is replaced with damaged tissue leaving a permanent scar in the liver. The damaged liver tissue may keep your liver from functioning properly.
Also, various liver diseases and conditions injure the healthy liver cells and result in hepatocyte cell death and inflammation. This is followed by cell repair and, finally, tissue scarring due to the repair process.
The damaged/scarred tissue inhibits the blood flow towards the liver. It hampers its ability to digest and process the various nutrients, medications, hormones, and natural toxins (poisons) that we consume in our day to day life. The liver also plays a vital role in producing proteins and other substances, which may be hampered due to liver disease like liver cirrhosis. Liver Cirrhosis treatment, when not undertaken at the right time, can become a life-threatening disorder.
Liver Cirrhosis is one of the deadliest complications, which is caused by liver diseases. Irreversible scarring and loss of liver cells are involved in Liver Cirrhosis. The major causes of Liver Cirrhosis are consumption of alcohol and Hepatitis B and Hepatitis C as well. There can be other causes and diseases which may lead to cirrhosis of the liver.
Liver Cirrhosis
Symptoms Of Liver Cirrhosis
People in the initial stages may go through a feeling of weakness, and there might be a sudden loss in weight without any particular reason. In the later stages, the patients may have jaundice. The following are the symptoms that a person suffering from Liver Cirrhosis may have in different parts of the body:
Abdomen: There may be severe pain in the abdomen region, and veins around the belly button may get enlarged.
Gastrointestinal: There may be bleeding occurrences, and fluids may start to accumulate in the abdomen. There can be an excessive formation of gas. The Excretion of dark stool is also a visible symptom.
Skin: Skin may turn yellow along with swelling of blood vessels that can be visible through the skin.
Mind: It not only affects the body but the mind as well; you may go through nausea and may feel a sense of confusion all the time.
Whole Body: You may gain or lose weight unintentionally without doing anything about it. There can be breast enlargement, dark urine, breathlessness, itching, vomiting of blood, etc
Other Services
Endoscopy
Colonoscopy
ERCP
Sigmoidoscopy
Pancreatic Disease
Liver Cirrhosis Treatment in Chandigarh
How can I prevent cirrhosis of the liver?
Liver cirrhosis treatment involves many lifestyle and dietary modifications which needs to be followed along with the medical treatment. Some of the lifestyle modifications for liver cirrhosis treat
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
2. Do you really love your liver ?Do you really love your liver ?
How can you love your liverHow can you love your liver
without knowing it ?without knowing it ?
After knowing it how can you doAfter knowing it how can you do
injustice to it ?injustice to it ?
3. Hi... I'm Your Liver !Hi... I'm Your Liver !
Let me tell you what I do forLet me tell you what I do for
you…inyou…in 99 waysways
4. II store the ironstore the iron reserves youreserves you
need, as well as a lot ofneed, as well as a lot of
vitamins and other minerals.vitamins and other minerals.
Without me, you wouldn'tWithout me, you wouldn't
have the strength to carryhave the strength to carry
on!on!
1.
I am responsible for up to 500
separate functions, usually in
combination with other systems
and organs.
5. I makeI make bilebile to help digestto help digest
your food,your food, without me,without me,
you'd wasteyou'd waste away to nothingaway to nothing
& dump me& dump me with poisonswith poisons..
2.
The bile produced by me is collected
in bile canalliculi, which merge to
form bile ducts.
6. II detoxify poisonousdetoxify poisonous
chemicalschemicals you give me, andyou give me, and
that includes alcohol, beer,that includes alcohol, beer,
wine and drugswine and drugs (prescribed(prescribed
and OTC)and OTC) as well as illegalas well as illegal
substances.substances.
3
Without me, your "bad“
habits would kill you.
7. I storeI store energyenergy,,
Like a battery, byLike a battery, by
Stockpiling sugarStockpiling sugar
(carbohydrates,(carbohydrates,
glucose and fat)glucose and fat)
Until you need it.Until you need it.
44
Without me, the sugar level in your
blood could fall dramatically and you'd
go into a coma.go into a coma.
8. You cann’t start your day in theYou cann’t start your day in the
morning, if I am not on the job !morning, if I am not on the job !
9. II make the bloodmake the blood that gotthat got
your system going evenyour system going even
before you were born,before you were born,
without me, you wouldn'twithout me, you wouldn't
be here !be here !
55
10. II manufacture new proteinsmanufacture new proteins that yourthat your
body needs to stay healthy and grow.body needs to stay healthy and grow.
Without me, you wouldn't grow properly!Without me, you wouldn't grow properly!
6
11. II remove poisonsremove poisons from thefrom the
air, exhaust smoke andair, exhaust smoke and
chemicals you breathe.chemicals you breathe.
7
Without me, you'd be
poisoned by
pollutants!
12. II make clotting factorsmake clotting factors thatthat
stop the bleeding when youstop the bleeding when you
accidentally prick yourself.accidentally prick yourself.
8
Without me, you'd
bleed To death !
13. I helpI help defend youdefend you against the germs goingagainst the germs going
into your body all the time. I take thoseinto your body all the time. I take those
cold germs, flu bugs and other germs youcold germs, flu bugs and other germs you
encounter, and knock them dead - or atencounter, and knock them dead - or at
least weaken them.least weaken them.
9
Without me,Without me,
you'd be ayou'd be a
sitting ducksitting duck
for everyfor every
infectioninfection
14. I hope now you understandI hope now you understand
how much I love you……..how much I love you……..
15. Let us understand the most commonLet us understand the most common
diseases that affect me……diseases that affect me……
16. FATTY LIVER DISEASEFATTY LIVER DISEASE
What is it?What is it?
• Fatty liverFatty liver is the collection ofis the collection of excessiveexcessive
amounts of fat inside liver cellsamounts of fat inside liver cells, also called, also called
steatosis.steatosis.
• Mostly triglycerides & CholesterolsMostly triglycerides & Cholesterols
• Reversible condition.Reversible condition.
17. FATTY LIVER - CAUSESFATTY LIVER - CAUSES
Fatty liver is commonly caused by AlcoholAlcohol oror
MetabolicMetabolic
Syndrome (Diabetes, Hypertension, Obesity and Dysli
demia), but can also be due to any one of many
causes.
1.1. NUTRITIONAL (MALNUTRITION/WEIGHT LOSS)NUTRITIONAL (MALNUTRITION/WEIGHT LOSS)
2.2. DRUGS & TOXINSDRUGS & TOXINS
3.3. VIRAL HEPATITISVIRAL HEPATITIS
4.4. AUTOIMMUNE LIVER DISEASEAUTOIMMUNE LIVER DISEASE
18. FATTY LIVER - CAUSESFATTY LIVER - CAUSES
• MetabolicMetabolic
AbetalipoproteinemiaAbetalipoproteinemia, G, Glycogen storage diseaseslycogen storage diseases, , Weber-Christian diseaseWeber-Christian disease, A, A
cute fatty liver of pregnancycute fatty liver of pregnancy, L, Lipodystrophyipodystrophy
• NutritionalNutritional
MalnutritionMalnutrition, T, Total parenteral nutritionotal parenteral nutrition, Severe , Severe weight lossweight loss, R, Refeedingefeeding
syndromesyndrome, J, Jejunoileal bypassejunoileal bypass, G, Gastric bypassastric bypass, Jejunal, Jejunal diverticulosisdiverticulosis
with with bacterial overgrowthbacterial overgrowth..
• Drugs and toxinsDrugs and toxins
AmiodaroneAmiodarone, M, Methotrexateethotrexate, D, Diltiazemiltiazem, Expired , Expired tetracyclinetetracycline, H, Highly activeighly active
antiretroviral therapyantiretroviral therapy, G, Glucocorticoidslucocorticoids, T, Tamoxifenamoxifen, Environmental , Environmental hepatotoxinshepatotoxins
Inflammtory bowel disease, HIV, hepatitis C and alpha 1-antitrypsin deficiencyInflammtory bowel disease, HIV, hepatitis C and alpha 1-antitrypsin deficiency
19. Alcoholic FattyAlcoholic Fatty
Liver orLiver or
AlcoholicAlcoholic
SteatosisSteatosis
causedcaused
By alcoholBy alcohol
abuseabuse
All body organs areAll body organs are
affected,affected,
with the liver and brainwith the liver and brain
suffering most seriously.suffering most seriously.
Alcoholic liver disease does not usually
cause any symptoms until the liver has
been extensively damaged. When this
happens, symptoms can include:
• NauseaNausea
• Weight lossWeight loss
• AnnorexiaAnnorexia
• Yellowing of the eyes and skin (Yellowing of the eyes and skin (jaundicejaundice))
• Swelling in the ankles and abdomenSwelling in the ankles and abdomen
• Confusion or drowsinessConfusion or drowsiness
20. Non-Alcoholic Fatty Liver DiseaseNon-Alcoholic Fatty Liver Disease
Affect people whoAffect people who
drink little or nodrink little or no
alcohol.alcohol.
Simple fatty liver (steatosis),Simple fatty liver (steatosis),
usually causes no liverusually causes no liver
damage but may lead to NASHdamage but may lead to NASH
Exact casue not knownExact casue not known
but Obesity & Insulinbut Obesity & Insulin
resistance lead toresistance lead to
progress of NAFLDprogress of NAFLD
Most patients have few or no symptoms,Most patients have few or no symptoms,
may complain of fatigue, malaise, andmay complain of fatigue, malaise, and
dull right-upper-quadrant abdominaldull right-upper-quadrant abdominal
discomfort.discomfort.
21. NonalcoholicNonalcoholic
steatohepatitis (NASH),steatohepatitis (NASH),
aa
more serious type.more serious type.
Caused by hepatitisCaused by hepatitis
infection, malnutrition,infection, malnutrition,
obesity, diabetesobesity, diabetes
mellitus,mellitus,
andand Reye's syndromeReye's syndrome ..
In some cases, this canIn some cases, this can
progress either toprogress either to
cirrhosis, which cancirrhosis, which can
produce progressive,produce progressive,
irreversible liver scarring,irreversible liver scarring,
or to liver cancer.or to liver cancer.
Fat in the liver, with inflammation
and damage, can occur in
children. Weight loss & weakness
may begin once the disease is
advanced or cirrhosis is present.
Reduce body weight, eat a
balanced diet, engage in physical
activity, and avoid alcohol and
unnecessary medications may
help in treatment as no specific
treatment available till date.
22. Reye's Syndrome:Reye's Syndrome:
A deadly disease, attack any child or adult without warning. A deadly disease, attack any child or adult without warning.
All body organs are affected, with theAll body organs are affected, with the
liver and brain suffering most seriously. liver and brain suffering most seriously.
Cause & cure remain unknown, research hasCause & cure remain unknown, research has
established a link between Reye's Syndromeestablished a link between Reye's Syndrome
And the use of aspirin and other salicylateAnd the use of aspirin and other salicylate
containing medications. containing medications.
23. Causes of NAFLD/NASH:Causes of NAFLD/NASH:
Unclear but researchers believe the contributing factors are:Unclear but researchers believe the contributing factors are:
• Obesity / Hypertension / Abnormal cholesterol levelsObesity / Hypertension / Abnormal cholesterol levels
• Insulin Resistance / DiabetesInsulin Resistance / Diabetes
• The fat may come from other parts of the body, or the liver mayThe fat may come from other parts of the body, or the liver may
absorbabsorb anan increasedincreased amount of fat from the intestine.amount of fat from the intestine.
• Another possible explanation is that the liver loses its ability toAnother possible explanation is that the liver loses its ability to
change fat into a form that can be eliminated.change fat into a form that can be eliminated.
24. What are the symptoms ?What are the symptoms ?
Fatty liver usually produces no symptoms butFatty liver usually produces no symptoms but
few patients may show the following symptoms:few patients may show the following symptoms:
• JaundiceJaundice
• Right-side abdominal painRight-side abdominal pain
• Abdominal swellingAbdominal swelling
• Fever.Fever.
• AnnorexiaAnnorexia
• FatigueFatigue
• Swollen LegsSwollen Legs
25. At more advanced stage, liverAt more advanced stage, liver
becomesbecomes cirrhotic:cirrhotic:
• Cirrhosis refers to scarring ofCirrhosis refers to scarring of
the liver. It replaces healthythe liver. It replaces healthy
tissue, cannot do what healthytissue, cannot do what healthy
liver tissue does.liver tissue does.
• Scar tissue also blocks theScar tissue also blocks the
normal flow of blood throughnormal flow of blood through
the liver, can be life-the liver, can be life-
threatening.threatening.
26. A fatty liver is enlarged and has a greasy, pale yellow look.A fatty liver is enlarged and has a greasy, pale yellow look.
27. NAFLD / NASH: Diagnosis ?NAFLD / NASH: Diagnosis ?
• The liver may be tender when the abdomen isThe liver may be tender when the abdomen is
pressed.pressed.
• Blood tests - for liver function (Enzymes)Blood tests - for liver function (Enzymes)
• Ultrasound or abdominal CT scan.Ultrasound or abdominal CT scan.
• Liver Biopsy (Grading of Steatosis)Liver Biopsy (Grading of Steatosis)
• Fibro-ScanFibro-Scan
• TSH Estimation (NASH-Marker)TSH Estimation (NASH-Marker)
28. NAFLD/NASH – Treatment ?NAFLD/NASH – Treatment ?
• Treatment for fatty liver is aimed at eliminating or treatingTreatment for fatty liver is aimed at eliminating or treating
the cause of the condition.the cause of the condition.
• In some cases, fatty liver is reversible if caught early in itsIn some cases, fatty liver is reversible if caught early in its
development.development.
• Pregnancy-related fatty liver is treated by delivering thePregnancy-related fatty liver is treated by delivering the
baby, if viable.baby, if viable.
• In severe cases, the patient may eventually require a liverIn severe cases, the patient may eventually require a liver
transplant.transplant.
• Drugs like: UDCA, Pentoxifylline, Vitamin-E, Statins,Drugs like: UDCA, Pentoxifylline, Vitamin-E, Statins,
Metformin, Pioglitazone, Metadoxine may help immensely.Metformin, Pioglitazone, Metadoxine may help immensely.
• Nutritional counselling, Weight reduction also helpNutritional counselling, Weight reduction also help
31. Fatty liver % detection vs no of check-up 2006Fatty liver % detection vs no of check-up 2006
Modality
2005
total check-up
2005
%
2006- total
check-up
2006
%
Ct Scan 1661 17.52 1132 24.12
Ultrasound 2627 9.82 3566 18.82
32. I KNOW STILL SOME PEOPLEI KNOW STILL SOME PEOPLE
DON’T LOVE ME ……DON’T LOVE ME ……
33. Let me tell you some easy waysLet me tell you some easy ways
to love me, ….. your liverto love me, ….. your liver
34. • Don't drown me in beer, alcohol orDon't drown me in beer, alcohol or
wine !wine !
• Even one drink is too much for someEven one drink is too much for some
people and could scar me for life.people and could scar me for life.
• Watch those drugs!Watch those drugs!
All drugs are chemicals, and when youAll drugs are chemicals, and when you
mix them up without a doctor's advicemix them up without a doctor's advice
you could create something poisonousyou could create something poisonous
35. • I scar easily due to repeatedI scar easily due to repeated
alcohol / drug abuse.. and thosealcohol / drug abuse.. and those
scars, called "cirrhosis" arescars, called "cirrhosis" are
permanent.permanent.
• TTaking unnecessary medicine isaking unnecessary medicine is
a bad habita bad habit. All those chemicals. All those chemicals
can really hurt me (liver).can really hurt me (liver).
• Sedentary life style or metabolicSedentary life style or metabolic
syndrome damage me most …syndrome damage me most …
please take careplease take care
36. Be careful withBe careful with aerosol spraysaerosol sprays !!
Remember, I have to detoxify what you breathe in, too. SoRemember, I have to detoxify what you breathe in, too. So
when you are cleaning with aerosol cleaners, make sure thewhen you are cleaning with aerosol cleaners, make sure the
room is ventilated, or wear a mask.room is ventilated, or wear a mask.
That goes double for bugThat goes double for bug
sprays, mildew sprays,sprays, mildew sprays,
Paint sprays and all thosePaint sprays and all those
Other chemical spraysOther chemical sprays
you use. Be careful whatyou use. Be careful what
you breathe!you breathe!
37. Watch what gets on your skin!Watch what gets on your skin! Those insecticides you put onThose insecticides you put on
trees and shrubs not only kill bugs they can get to me righttrees and shrubs not only kill bugs they can get to me right
through your skin and destroy my cells, toothrough your skin and destroy my cells, too. Remember. Remember
they're all chemicalsthey're all chemicals. Cover your skin with gloves, long. Cover your skin with gloves, long
sleeves, a hat and mask every time insecticides are in thesleeves, a hat and mask every time insecticides are in the
air or if you're handling them.air or if you're handling them.
38. Don't eat too muchDon't eat too much fattyfatty
foodfood !!
I make the cholesterol yourI make the cholesterol your
body needs,body needs, and I try to makeand I try to make
the right amount.the right amount.
Give me a break.Give me a break. Eat a good,Eat a good,
well balanced nourishing diet.well balanced nourishing diet.
If you eat the right stuff forIf you eat the right stuff for
me, I'll really do my stuff forme, I'll really do my stuff for
you!you!
39. WARNING:WARNING:
I can't and won't tell you I'm inI can't and won't tell you I'm in
trouble until I'm almost at thetrouble until I'm almost at the
end of my rope... and yours.end of my rope... and yours.
Remember:Remember: I am a nonI am a non
complainer.complainer.
Overloading me with drugs, alcoholOverloading me with drugs, alcohol
and other junk can destroy me !and other junk can destroy me !
This may be the only warning youThis may be the only warning you
will ever getwill ever get..
40. Take My Advice, Please!Take My Advice, Please!
• Check me out with your doctor regularly.Check me out with your doctor regularly.
• Blood screening tests can identify some trouble.Blood screening tests can identify some trouble.
If I'm soft and smooth, that's good. If
I'm hard and bumpy, that could mean
a trouble, take needful actions.
If your doctor suspects trouble, USG
and CT scans can look into it.
My life, and yours, depends on how
you treat me and love me.
41. Now you know how much I care forNow you know how much I care for you.you.
Please treatPlease treat meme with tender loving care.with tender loving care.
I am your silent partner in all vitalI am your silent partner in all vital
Actions of life and …. Love youActions of life and …. Love you