This document provides an introduction to the Ayurvedic concepts of Karya (effect) and Karana (cause). It discusses how everything that exists can be explained through the Karya-Karana framework. It describes the three types of causes - Samavayi (inherent), Asamavayi (non-inherent) and Nimitta (instrumental). Various philosophies regarding the manifestation of effects from causes are also mentioned. The significance of Karya-Karana thinking in understanding topics like disease pathogenesis, treatment principles and universal creation/evolution is highlighted. Key Ayurvedic concepts like Doshas, Dhatus, Nidanas etc. can be explained using this causal