Jules bordet
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Jules Bordet was a Belgian bacteriologist and immunologist who was born in 1870. He studied medicine at the Free University of Brussels and graduated in 1892. In 1919, Bordet received the Nobel Prize in Physiology or Medicine for his discoveries relating to immunity. Through his studies of cholera in 1896, Bordet concluded that there are two types of factors in the blood that fight infection: antibodies formed during immunization against specific bacteria, and complement proteins that exist in non-immunized blood. This established the principle that antibodies and complement proteins work together, a principle still used today in disease testing.
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Jules bordet
- 1. Jules Bordet (13 Jun 1870 - 6 Apr 1961) Belgian bacteriologist and immunologist “ Science defeats Darkness” Prepared by : Jyotirmayee Sahoo Aakash Verma Aditya Amrut Pawar 1
- 2. Early Life and Education • Jules Bordet was born at Soignies , Belgium in 1870 • He graduated as Doctor of Medicine from the Free University of Brussels in 1892 • He got Noble Prize in Physiology or Medicine in 1919 for his discoveries relating to immunity • He was affiliated to Brussels University, Brussels, Belgium at the time when he got Noble Prize 2
- 3. Noble Prize Work • Our immune system protects us from attacks by microorganisms and poisonous substances • The blood includes factors or bodies that destroy bacteria • By doing studies of cholera in 1896, Jules Bordet came into conclusion that there are two types of factors in the blood: 1.Antibodies formed by immunization against specific bacteria 2.Complement proteins that also exist in blood that is not immunized. • Antibodies and complement proteins are bound to one another, which can be used to detect certain diseases, including syphilis • By following the principles of Bordet work, the same principle is used today in serologic testing of countless diseases 3
- 4. References • Jules Bordet – Facts. NobelPrize.org. Nobel Media AB 2018. Sun. 19 Aug 2018. https://www.nobelprize.org/prizes/medicine/1919/bordet/facts/> • Schmalstieg Jr, Frank C., and Armond S. Goldman. "Jules Bordet (1870–1961): a bridge between early and modern immunology." Journal of medical biography 17.4 (2009): 217- 224. 4
Editor's Notes
- The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane. It is part of the innate immune system