This document presents the results of a parametric study to optimize the design of post-tensioned concrete box-girder pedestrian bridges with main spans ranging from 30 to 60 meters. An optimization algorithm called SAMO2 was used to minimize the cost by varying 33 design variables related to geometry, materials, and construction. The optimal solutions showed that depth and number of prestressing strands correlated with main span length, while slab thicknesses generally took minimum allowed values. Increasing the main span by 1 meter on average increased total cost by 6.38 euros per square meter. Concrete strength varied between 35 to 55 MPa but tended to increase with longer spans.