Here are the responses to your questions: 1. Comeaux and Comeaux identified unrelieved postoperative pain as the clinical problem, while Li et al. identified insufficient evidence on the effects of music therapy on state anxiety of breast cancer patients following radical mastectomy. 2. Comeaux and Comeaux used a quasi-experimental nonequivalent control group design, while Li et al. used a randomized controlled design. A randomized controlled design is more powerful because it reduces selection bias. The researchers could have improved their designs by randomizing participants to increase internal validity. 3. Comeaux and Comeaux may have selected their design because randomization was not feasible due to room assignments. 4. The control groups in both studies received