Ortho and grid drawing aids can help with positioning and alignment when drawing in AutoCAD. Ortho constrains movement to axes while grid provides regularly spaced dots. There are three main ways to draw in AutoCAD - using the draw toolbar, draw pull down menu, or keyboard shortcuts like 'L' for line. Text, hatching and other objects can be drawn using specific toolbars and menu options. Layers allow organizing and managing objects in AutoCAD.