4. Introduction to BONE SCAN-1
• BONE SCAN is one of the most commonly
performed nuclear medicine procedure
world wide.
• Its very feasible and cost effective way of
scanning whole of the skeleton with single
injection at very low cost financially and
lower radiation exposure burden.
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY,
BANNU
5. Introduction to BONE SCAN-2
• Very important fact while
referring for bone scan and
interpreting the bone scan is…
HIGH SENSITIVITY
LOW SPECIFICITY
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY,
BANNU
6. Introduction to BONE SCAN-3
• Various chemical agents have been used
for bone scan and Technetium 99m
labeled MDP is agent of choice these days
• The mechanism of localization of Tc99m-
MDP is dependant on blood flow and
adsorption of agent on hydroxy-appatite of
the bones
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
7. Introduction to BONE SCAN-4
• Bone scan may performed in
many ways according to
indication for it
Whole body bone scan
Spot views
Three phase bone scan
SPECT bone scan
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
9. INDICATIONS for BONE SCAN
• Oncology
• Orthopedics
• Others
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
10. INDICATIONS for BONE SCAN/
ONCOLOGY
• Primary bone tumors
• Skeletal Metastasis (staging)
• Extension of soft tissue
neoplasms to bone
• Treatment Response evaluation
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
11. INDICATIONS for BONE SCAN/
ORTHOPEDICS
• Trauma
• Fractures
• Prosthesis evaluation
• Infectious bone diseases
• Bone viability
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
12. INDICATIONS for BONE SCAN/
others
• Metabolic bone disease
• Paget’s disease
• A-symmetric mandibular
growth
• Un-explained bone pain
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU