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BONE SCINTIGRAPHY
INTRODUCTION &
INDICATIONS
Dr. AMIR BAHADUR
Nuclear Medicine Physician
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
Presentation Outline
• Introduction to bone scan
• Indications for bone scan
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY,
BANNU
Introduction to BONE SCAN-1
• BONE SCAN is one of the most commonly
performed nuclear medicine procedure
world wide.
• Its very feasible and cost effective way of
scanning whole of the skeleton with single
injection at very low cost financially and
lower radiation exposure burden.
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY,
BANNU
Introduction to BONE SCAN-2
• Very important fact while
referring for bone scan and
interpreting the bone scan is…
HIGH SENSITIVITY
LOW SPECIFICITY
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY,
BANNU
Introduction to BONE SCAN-3
• Various chemical agents have been used
for bone scan and Technetium 99m
labeled MDP is agent of choice these days
• The mechanism of localization of Tc99m-
MDP is dependant on blood flow and
adsorption of agent on hydroxy-appatite of
the bones
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
Introduction to BONE SCAN-4
• Bone scan may performed in
many ways according to
indication for it
 Whole body bone scan
 Spot views
 Three phase bone scan
 SPECT bone scan
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
INDICATIONS for BONE SCAN
• Oncology
• Orthopedics
• Others
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
INDICATIONS for BONE SCAN/
ONCOLOGY
• Primary bone tumors
• Skeletal Metastasis (staging)
• Extension of soft tissue
neoplasms to bone
• Treatment Response evaluation
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
INDICATIONS for BONE SCAN/
ORTHOPEDICS
• Trauma
• Fractures
• Prosthesis evaluation
• Infectious bone diseases
• Bone viability
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
INDICATIONS for BONE SCAN/
others
• Metabolic bone disease
• Paget’s disease
• A-symmetric mandibular
growth
• Un-explained bone pain
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU

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Introduction and indications of BONE SCAN

  • 1. BONE SCINTIGRAPHY INTRODUCTION & INDICATIONS Dr. AMIR BAHADUR Nuclear Medicine Physician BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 2. Presentation Outline • Introduction to bone scan • Indications for bone scan BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 3. BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 4. Introduction to BONE SCAN-1 • BONE SCAN is one of the most commonly performed nuclear medicine procedure world wide. • Its very feasible and cost effective way of scanning whole of the skeleton with single injection at very low cost financially and lower radiation exposure burden. BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 5. Introduction to BONE SCAN-2 • Very important fact while referring for bone scan and interpreting the bone scan is… HIGH SENSITIVITY LOW SPECIFICITY BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 6. Introduction to BONE SCAN-3 • Various chemical agents have been used for bone scan and Technetium 99m labeled MDP is agent of choice these days • The mechanism of localization of Tc99m- MDP is dependant on blood flow and adsorption of agent on hydroxy-appatite of the bones BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 7. Introduction to BONE SCAN-4 • Bone scan may performed in many ways according to indication for it  Whole body bone scan  Spot views  Three phase bone scan  SPECT bone scan BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 8. BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 9. INDICATIONS for BONE SCAN • Oncology • Orthopedics • Others BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 10. INDICATIONS for BONE SCAN/ ONCOLOGY • Primary bone tumors • Skeletal Metastasis (staging) • Extension of soft tissue neoplasms to bone • Treatment Response evaluation BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 11. INDICATIONS for BONE SCAN/ ORTHOPEDICS • Trauma • Fractures • Prosthesis evaluation • Infectious bone diseases • Bone viability BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 12. INDICATIONS for BONE SCAN/ others • Metabolic bone disease • Paget’s disease • A-symmetric mandibular growth • Un-explained bone pain BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU
  • 13. BANNU INSTITUTE OF NUCLEAR MEDICINE, ONCOLOGY & RADIOTHERAPY, BANNU