The document discusses innovation and change, focusing on small and medium Italian enterprises. It argues that collaboration and cooperation, rather than competition, should be at the heart of innovation to tackle problems facing these businesses. As an example, it outlines the "Stand Up to Cancer" initiative in the US that transformed cancer research through collaboration. It then provides statistics on unemployment and poverty in Italy to argue the economic model needs rethinking, and that a collaborative national task force could help innovate markets and trade for small and medium enterprises.