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INFECTION CONTROL
INFECTION CONTROL
 Health care associated infection
greatest risk a patient faces on
admission to a hospital
A QUICK SURVEY
How many of you
 Have encountered Nosocomial
Infections?
 Have disclosed to families that
it is a NI?
 Analyzed root cause of NI?
 Optimized your efforts to
prevent it?
LET’S FACE REALITY
 Who pays for morbidity and additional
costs related to NI?
 What happens if third party payment is
denied for NI?
Medicare in USA
 Do we have benchmarks?
BIG FOUR…
 Urinary tract infection
 Surgical site infection
 Pneumonia
 Blood stream infection
 Prevention better than cure
 20% can be prevented
 Infection control is the foundation
WHERE TO LOOK FOR?
 Tubes- ETT, RT, Foley, TT
 Lines- peripheral, central and arterial
 Personnel-doctors,nurses, care givers
HOW DO WE GO ABOUT…
 Standard precaution
 Transmission barrier
 Education
 Surveillance
ALCOHOL BASED HAND RUB-GOLD
STANDARD
1. Terminates out breaks
2. Decreases transmission of MRSA
3. Gloves is not the answer
4. Allergic contact dermatitis
5. Generates more time
Routine Hand Hygiene
Ref; ISCCM 2003 guidelines
The scrub should be performed
for a minimum of 2-3 minutes
Procedural Hand HygiEne
Ref; ISCCM 2003 guidelines
The scrub should be
performed for a
minimum of 2-3 minutes
Hand drying - use sterile
(autoclaved) towels
LINES
 Peripheral
 Central
 Arterial
INSERTION OF PERIPHERAL IV
CATHETERS
Ref; ISCCM 2003
Guidelines
once prepared, the site of insertion should not be palpated
FLUSHING PERIPHERAL
LINES
CENTRAL LINE
 Insertion
 Maintenance
 Replacement
INSERTION
 Empowerment
 Insertion cart or kit
 Maximal sterile barrier
 Site
CENTRAL LINE INSERTION
BUNDLE
 Hand Hygiene
 Maximal Sterile Barrier Precautions
 Chlorhexidine Skin Asepsis
 Optimal Catheter Site Selection
MAINTENANCE
 Dressing
 Any role for systemic antibiotics
 Topical antibiotic
 Anticoagulant flush/ heparin lock
CENTRAL LINE MAINTENANCE
BUNDLE
 Daily review of Central Line necessity and
prompt removal of unnecessary lines
 Dedicated lumen for TPN
 Accessing the lumens aseptically
 Checking entry site during every dressing
change
HAND HYGIENE
strictly followed (even when gloves are worn) before and after
injection, blood sampling, dressing or any contact with the CVC or
insertion site
Ref; ISCCM 2003 Guidelines
TECHNIQUE OF BLOOD
SAMPLING
Gauze dressing
Transparent
dressing
MAINTENANCE OF CENTRAL
LINES - DRESSING CHANGE
POORLY MAINTAINED
CENTRAL LINE BUNDLE
COMPLIANCE
Intervention Compliance
Hand Hygiene 62%
Chlorhexidine antiseptic at
procedure site
100%
Draped entire patient in a sterile
fashion
85%
Used cap, mask & sterile gown 92%
Used Sterile gloves 100%
Sterile dressing applied 100%
REPLACEMENT
 Routine line change not needed
 Purulence
 If not needed- plastic is out
 Over the guidewire exchange- No, No
 Emergency line< 48 hrs
CARE OF PRESSURE MONITORING
SYSTEM
 Closed continuous flush system
 No dextrose containing solution
 Minimal manipulation
 No antibiotic lock technique
REPLACEMENT….
 Disposable transducer system- 96 hours
 Reusable transducer system- 48 hours
Chlorhexidine versus Povidone-
Iodine Solution
Ref; Chlorhexidine Compared with Povidone-Iodine Solution for Vascular Catheter–Site Care: A Meta-Analysis Nathorn
Chaiyakunapruk, PharmD, PhD; David L. Veenstra, PharmD, PhD; Benjamin A. Lipsky, MD; and Sanjay Saint, MD, MPH
Ann Intern Med. 2002;136:792-801.
Chlorhexidine is superior
 blood, serum, and other
protein-rich biomaterials can
deactivate the microbicidal
effect of povidone-iodine but
not chlorhexidine
 the residual effect defined as
the long-term antimicrobial
suppressive activity is
prolonged (at least 6 hours)
 reduces the colony counts of
coagulase-negative
staphylococci
URINARY CATHETER
 CAUTI – What does it mean?
 40% of all nosocomial infections
 Types of catheter
1. Short term
2. Long term indwelling
CAUTI
 Infection!! Why?
 Common mechanism
1. Extraluminal
2. Intraluminal
PREVENTION
 Closed drainage system
 Restricted catheter use
 Aseptic technique
 Unobstructed urine flow
 Catheter size
WHAT CAN WE DO?
 Catheter management
 Taping and anchorage
 Cleaning
 Disinfectant!!!
 Collection bag
 Discontinuation
 Transport
 Suprapubic catheter
 Bladder irrigation
 Antimicrobial coated catheter
 Condom catheter
WHEN DO YOU REPLACE?
 Suspected UTI
 Decreases bacterial load
 Antibiotic penetrate biofilm poorly
URINARY CATHETER
Urine sample collection
 Urine can be aspirated
from the catheter itself
or through a port
designed specifically for
that purpose, but should
not be taken from the
collection bag.
 Remove an indwelling
catheter and sample urine
using a new catheter,
when possible Ref: Thomas Fekete UpToDate 2008
ENDOTRACHEAL TUBE MANAGEMENT
Orogastric tubes also
preferred
over nasogastric
Nasal tubes obstruct
maxillary antral drainage
The orotracheal route is
preferred for intubation
Nasal route
only
as an
exception
SECURING THE ET TUBE
Method 1: Using standard sticking plaster
(eg. Johnsonplast®
)
Apply short strip to long 1” strip
“ sticky” side up
tails
Tail secures
tube
Tail
fixes to lip
Method 2: Using twill tape tie
“Cow hitch”
“Clove Hitch”
Method 3:
Commercially
manufactured holders
are now available
SECURING THE ET TUBE
CONFIRMING TUBE POSITION
Besides auscultation, always confirm ET tube
position on a chest radiograph
Remember! Neck position affects
ET tube tip movement.
ET tip about 4cms above carina; level of aortic knob
Always note the distance of the tube at the incisor teeth
VENTILATOR ASSOCIATED PNEUMONIA
 48-72 hours of ventilation
 Progressive new infiltrates in CXR
 Leukocytosis and purulent
tracheobronchial secretions
HOW DO YOU PREVENT
 Patient positioning
30-45 º
Semi-recumbent position
SUPRAGLOTTIC CARE
Continuous aspiration of supraglottic collection
will reduce VAP rates (needs special tube)
Accumulation of supraglottic
secretions; may be aspirated
with pressures not > 20 cm H2O.
Specialised tube with a channel
opening above the balloon
ORAL CARE
Regular mouth care to clear oral secretions &
administer antiseptics (chlorhexidine)
Preferably 8 hourly
Remove oral airway
Move ET tube to opposite corner
Clear mouth of all secretions
Paint mouth with 2% chlorhexidine
Reduces rates of VAP
 No evidence to prefer CSS over OSS
 Cuff pressure
 Heated Vs unheated circuit
 Artificial nose Vs humidification
 Stress ulcer prophylaxis
Contact isolation
 For patients with multi-drug resistant bacteria
 Consists of standard precautions plus unsterile
gloves whenever patient is touched, then
handwashing or hand rub immediately
 Plastic gowns if extensive patient contact likely
 Dedicated equipment eg stethoscope, BP apparatus
 Sign at head of bed
 Single room or cohort nursing
 One on one nursing essential
CONTACT ISOLATION
 Standard precautions plus contact precautions
plus:
 Private room or sharing of room with anyone
with a similar illness; if not feasible, patients
should be minimum of 3 feet apart
 Surgical masks for anyone who goes within 3
feet of patient
 Patient masked when transported outside room
 For respiratory viruses
DROPLET ISOLATION
 For PTb, Varicella, Rubella
 Spreads beyond 3ft
 Separate room with ante-
room
& negetive pressure
 No re-circulation of air
 6–12 exchanges per hour
 One per 100 beds
 Proper mask – N95
AIRBORNE ISOLATION
FUTURE IS LOOKING….
 Dramatic proliferation of MDR
organisms
 No new antibiotic in the horizon
 Mushrooming of ICUs in smaller towns
 Lack of strict adherence to protocols
MAY DAY! MAY DAY!
ZERO RESISTANCE – SPANISH
ARMADA
 Zero VAP and zero bacteremia
 Dedicated intensivist
 Exclusive infection control nurse
 Active surveillance
 Standardised cleaning protocol
 Built in educational modules
TAKE HOME MESSAGE
 Alcohol based hand rub is an eye opener
 Routine line change not needed
 Prophylactic antibiotic- definite NO
 Closed drainage system is a must
 30-40º semi-recumbent position
 Breaking myths , beliefs and barriers
 Advocating zero tolerance
 Rationale outlook towards local needs
YES WE CAN
THANK YOU

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Infection control

  • 2. INFECTION CONTROL  Health care associated infection greatest risk a patient faces on admission to a hospital
  • 3. A QUICK SURVEY How many of you  Have encountered Nosocomial Infections?  Have disclosed to families that it is a NI?  Analyzed root cause of NI?  Optimized your efforts to prevent it?
  • 4. LET’S FACE REALITY  Who pays for morbidity and additional costs related to NI?  What happens if third party payment is denied for NI? Medicare in USA  Do we have benchmarks?
  • 5. BIG FOUR…  Urinary tract infection  Surgical site infection  Pneumonia  Blood stream infection
  • 6.  Prevention better than cure  20% can be prevented  Infection control is the foundation
  • 7. WHERE TO LOOK FOR?  Tubes- ETT, RT, Foley, TT  Lines- peripheral, central and arterial  Personnel-doctors,nurses, care givers
  • 8. HOW DO WE GO ABOUT…  Standard precaution  Transmission barrier  Education  Surveillance
  • 9. ALCOHOL BASED HAND RUB-GOLD STANDARD 1. Terminates out breaks 2. Decreases transmission of MRSA 3. Gloves is not the answer 4. Allergic contact dermatitis 5. Generates more time
  • 10. Routine Hand Hygiene Ref; ISCCM 2003 guidelines The scrub should be performed for a minimum of 2-3 minutes
  • 11. Procedural Hand HygiEne Ref; ISCCM 2003 guidelines The scrub should be performed for a minimum of 2-3 minutes Hand drying - use sterile (autoclaved) towels
  • 13. INSERTION OF PERIPHERAL IV CATHETERS Ref; ISCCM 2003 Guidelines once prepared, the site of insertion should not be palpated
  • 15. CENTRAL LINE  Insertion  Maintenance  Replacement
  • 16. INSERTION  Empowerment  Insertion cart or kit  Maximal sterile barrier  Site
  • 17. CENTRAL LINE INSERTION BUNDLE  Hand Hygiene  Maximal Sterile Barrier Precautions  Chlorhexidine Skin Asepsis  Optimal Catheter Site Selection
  • 18. MAINTENANCE  Dressing  Any role for systemic antibiotics  Topical antibiotic  Anticoagulant flush/ heparin lock
  • 19. CENTRAL LINE MAINTENANCE BUNDLE  Daily review of Central Line necessity and prompt removal of unnecessary lines  Dedicated lumen for TPN  Accessing the lumens aseptically  Checking entry site during every dressing change
  • 20. HAND HYGIENE strictly followed (even when gloves are worn) before and after injection, blood sampling, dressing or any contact with the CVC or insertion site Ref; ISCCM 2003 Guidelines
  • 22. Gauze dressing Transparent dressing MAINTENANCE OF CENTRAL LINES - DRESSING CHANGE
  • 24. CENTRAL LINE BUNDLE COMPLIANCE Intervention Compliance Hand Hygiene 62% Chlorhexidine antiseptic at procedure site 100% Draped entire patient in a sterile fashion 85% Used cap, mask & sterile gown 92% Used Sterile gloves 100% Sterile dressing applied 100%
  • 25. REPLACEMENT  Routine line change not needed  Purulence  If not needed- plastic is out  Over the guidewire exchange- No, No  Emergency line< 48 hrs
  • 26. CARE OF PRESSURE MONITORING SYSTEM  Closed continuous flush system  No dextrose containing solution  Minimal manipulation  No antibiotic lock technique
  • 27. REPLACEMENT….  Disposable transducer system- 96 hours  Reusable transducer system- 48 hours
  • 28. Chlorhexidine versus Povidone- Iodine Solution Ref; Chlorhexidine Compared with Povidone-Iodine Solution for Vascular Catheter–Site Care: A Meta-Analysis Nathorn Chaiyakunapruk, PharmD, PhD; David L. Veenstra, PharmD, PhD; Benjamin A. Lipsky, MD; and Sanjay Saint, MD, MPH Ann Intern Med. 2002;136:792-801. Chlorhexidine is superior  blood, serum, and other protein-rich biomaterials can deactivate the microbicidal effect of povidone-iodine but not chlorhexidine  the residual effect defined as the long-term antimicrobial suppressive activity is prolonged (at least 6 hours)  reduces the colony counts of coagulase-negative staphylococci
  • 29. URINARY CATHETER  CAUTI – What does it mean?  40% of all nosocomial infections  Types of catheter 1. Short term 2. Long term indwelling
  • 30. CAUTI  Infection!! Why?  Common mechanism 1. Extraluminal 2. Intraluminal
  • 31. PREVENTION  Closed drainage system  Restricted catheter use  Aseptic technique  Unobstructed urine flow  Catheter size
  • 32. WHAT CAN WE DO?  Catheter management  Taping and anchorage  Cleaning  Disinfectant!!!  Collection bag  Discontinuation  Transport
  • 33.  Suprapubic catheter  Bladder irrigation  Antimicrobial coated catheter  Condom catheter
  • 34. WHEN DO YOU REPLACE?  Suspected UTI  Decreases bacterial load  Antibiotic penetrate biofilm poorly
  • 35. URINARY CATHETER Urine sample collection  Urine can be aspirated from the catheter itself or through a port designed specifically for that purpose, but should not be taken from the collection bag.  Remove an indwelling catheter and sample urine using a new catheter, when possible Ref: Thomas Fekete UpToDate 2008
  • 37. Orogastric tubes also preferred over nasogastric Nasal tubes obstruct maxillary antral drainage The orotracheal route is preferred for intubation Nasal route only as an exception
  • 38. SECURING THE ET TUBE Method 1: Using standard sticking plaster (eg. Johnsonplast® ) Apply short strip to long 1” strip “ sticky” side up tails Tail secures tube Tail fixes to lip
  • 39. Method 2: Using twill tape tie “Cow hitch” “Clove Hitch” Method 3: Commercially manufactured holders are now available SECURING THE ET TUBE
  • 40. CONFIRMING TUBE POSITION Besides auscultation, always confirm ET tube position on a chest radiograph Remember! Neck position affects ET tube tip movement. ET tip about 4cms above carina; level of aortic knob Always note the distance of the tube at the incisor teeth
  • 41. VENTILATOR ASSOCIATED PNEUMONIA  48-72 hours of ventilation  Progressive new infiltrates in CXR  Leukocytosis and purulent tracheobronchial secretions
  • 42. HOW DO YOU PREVENT  Patient positioning 30-45 º Semi-recumbent position
  • 43. SUPRAGLOTTIC CARE Continuous aspiration of supraglottic collection will reduce VAP rates (needs special tube) Accumulation of supraglottic secretions; may be aspirated with pressures not > 20 cm H2O. Specialised tube with a channel opening above the balloon
  • 44. ORAL CARE Regular mouth care to clear oral secretions & administer antiseptics (chlorhexidine) Preferably 8 hourly Remove oral airway Move ET tube to opposite corner Clear mouth of all secretions Paint mouth with 2% chlorhexidine Reduces rates of VAP
  • 45.  No evidence to prefer CSS over OSS  Cuff pressure  Heated Vs unheated circuit  Artificial nose Vs humidification  Stress ulcer prophylaxis
  • 46. Contact isolation  For patients with multi-drug resistant bacteria  Consists of standard precautions plus unsterile gloves whenever patient is touched, then handwashing or hand rub immediately  Plastic gowns if extensive patient contact likely  Dedicated equipment eg stethoscope, BP apparatus  Sign at head of bed  Single room or cohort nursing  One on one nursing essential CONTACT ISOLATION
  • 47.  Standard precautions plus contact precautions plus:  Private room or sharing of room with anyone with a similar illness; if not feasible, patients should be minimum of 3 feet apart  Surgical masks for anyone who goes within 3 feet of patient  Patient masked when transported outside room  For respiratory viruses DROPLET ISOLATION
  • 48.  For PTb, Varicella, Rubella  Spreads beyond 3ft  Separate room with ante- room & negetive pressure  No re-circulation of air  6–12 exchanges per hour  One per 100 beds  Proper mask – N95 AIRBORNE ISOLATION
  • 49. FUTURE IS LOOKING….  Dramatic proliferation of MDR organisms  No new antibiotic in the horizon  Mushrooming of ICUs in smaller towns  Lack of strict adherence to protocols MAY DAY! MAY DAY!
  • 50. ZERO RESISTANCE – SPANISH ARMADA  Zero VAP and zero bacteremia  Dedicated intensivist  Exclusive infection control nurse  Active surveillance  Standardised cleaning protocol  Built in educational modules
  • 51. TAKE HOME MESSAGE  Alcohol based hand rub is an eye opener  Routine line change not needed  Prophylactic antibiotic- definite NO  Closed drainage system is a must  30-40º semi-recumbent position
  • 52.  Breaking myths , beliefs and barriers  Advocating zero tolerance  Rationale outlook towards local needs YES WE CAN