Harish Sharma completed an industrial training report at Naxpar Pharmaceuticals in Baddi, Himachal Pradesh, India to fulfill requirements for his B.Pharm degree. The report provides details about Naxpar's production processes, equipment, quality control procedures, and storage and distribution operations. It describes the company's manufacturing of tablets including active and inactive ingredients, unit operations like wet and dry granulation, and tableting. Quality control testing and standard operating procedures are also outlined. The training gave Harish valuable experience in pharmaceutical production and distribution that he can apply to further his career.

1. Industrial Training Report
For partial fulfillment of B.Pharm 6TH
Semester
Session 2018-19
Dr. A.P.J Abdul Kalam Technical University
Lucknow
Ashoka Institute Of Technology And Management
Varanasi
Submitted By:
Name: HARISH SHARMA
Roll no: 1564150022

2. CERTIFICATE
This is to certify that Mr. HARISH SHARMA has submitted the report on Industrial training
for partial fulfilment of B. Pharm 6th Semester, session 2018-2019. The contents of the report do
not form the basis for the award of any other degree to the candidate or to anybody else from this
or any other University/Institution.
Dr. BRIJESH SINGH
(Industrial Training Incharge)
AITM Varanasi
HEAD OF DEPARTMENT......................................................................................
EXTERNAL EXAMINER........................................................................................
DIRECTOR OF PHARMACY.................................................................

3. ACKNOWLEDGEMENT
The training opportunity I had with Naxpar Pharmaceutical Baddi Himachal Pradesh, was a
great chance for learning and professional development. Therefore, I consider myself as a very
lucky individual as I was provided with an opportunity to be a part of it. I am also grateful for
having a chance to meet so many wonderful people and professionals who led me though this
training period.
I am using this opportunity to express my deepest gratitude and special thanks to Ashoka
Institute of Technology and Management varanasi who in spite of being extraordinarily busy
with their duties gave us an opportunity so that we could learn something so important.
I express my deepest thanks to Mr.Mathew John (General Manager) of Naxpar
Pharmaceutical Baddi Himachal Pradesh and Mr.Jitesh Sharma (Production supervisior) for
taking part in useful decision & giving necessary advices and guidance and arranged all facilities
to make life easier. I choose this moment to acknowledge his contribution gratefully.
I perceive as this opportunity as a big milestone in my career development. I will strive to use
gained skills and knowledge in the best possible way, and I will continue to work on their
improvement.
Thanking You . HARISH SHARMA
B.PHARM 3RD YEAR
ROLLNO. 1564150022

4. CONTENTS
1. INTRODUCTION…………………………………………………1
1.1. Products………………………………………………………1
1.2. Services…………………………………………………….....1
1.3. Infrastructure……………………………………………….…3
1.4. Clients…………………………………………………………3
2. PRODUCTION SECTION…………………………………………3
A. Active Ingredients…………………………………………………….3
B. Non active Ingredient……………………………………………….. 3
3. UNIT OPERATION…………………………………………………………...4
a. Wet granulation………………………………………………………….4
b. Dry granulation…………………………………………………………..4
c. Direct compression……………………………………………………....4
4. EQUIPMENTS……………………………………………………………6
 Sifter …………………………………………………………………6
 Planetary mixer……………………………………………………….6
 Mass Mixer……………………………………………………………6
 Multi mill……………………………………………………………..6
 Fluidized bed dryer……………………………………………………6
 Tray Dryer…………………………………………………………….6
 Compression…………………………………………………………..7
 Tablet Presses…………………………………………………………7
5. Coating………………………………………………………………………..8
 Sugar Coating………………………………………………………………….8
 Film Coating…………………………………………………………………...8
 Organic film coating……………………………………………………………8
 Aqueous film coating…………………………………………………………...8
6. Packaging and labeling of tablets……………………………………………9
A. Packaging……………………………………………………………….9
B. Package labeling or labeling……………………………………………9
Types of packaging……………………………………………………………………9
 Blister packing………………………………………………………………….9

5.  Strip packing……………………………………………………………………..10
7. Quality control section…………………………………………………………10
8. SOPs (STANDARD OPERATING PROCEDURE)…………………………15
A. SOPs for Compression Machine…………………………………………15
B. SOPs for Blister Packing Machine……………………………………….16
C. SOPs for Disintegration Test Apparatus…………………………………17
D. SOPs for Friability Test Apparatus……………………………………….17
9. BATCH MANUFACTURING RECORD (BMR)……………………………….18
a. Batch records bill of Material………………………………………………………..18
b. General instruction for manufacturing……………………………………………….18
c. Equipment cleaning record…………………………………………………………..19
d. Yield………………………………………………………………………………….19
e. Abbreviations…………………………………………………………………………19
10.R.M & P.M Area (WAREHOUSE)……………………………………………………..19
 PRINCIPLES OF WAREHOUSE LAYOUTPRINCIPLES OF WAREHOUSE
LAYOUT DESIGNDESIGN……………………………………………………………19
 STOCK LOCATION Objectives ………………………………………………………20
 PHYSICAL CONTROL & SECURITY ELEMENTS…………………………………20
11. STORAGE AND DISTRIBUTION……………………………………21
A. RESPONSIBILITIES……………………………………………………………21
B. LABELING CONSIDERATIONS FOR DRUG PRODUCTS…………………22
C. STORAGE LOCATIONS AND PROCESSES…………………………………23
D. STORAGE IN BUILDINGS AND FACILITIES……………………………….23
E. RECEIVING AND TRANSFERRING DRUG PRODUCTS…………………..23

6. F. REFRIGERATORS AND FREEZERS………………………………………..24
G. PACKAGING FOR THE DISTRIBUTION AND TRANSPORTATION
PROCESSES……………………………………………………………………25
12.CONCLUSION ……………………………………………………….30
13.REFERENCES ………………………………………………………..31