This document discusses several patient cases that raise issues around infection control and antimicrobial stewardship in hospitals. It addresses challenges like limited isolation room availability, proper use and charging of personal protective equipment, prompt notification of multidrug-resistant organism results, pre-operative antimicrobial timing, HIV screening consent and confidentiality, opportunistic infection precautions, and establishing effective communication between nurses, doctors and pharmacists regarding antibiotic duration. The document uses these case examples to illustrate common problems encountered in infection prevention and antibiotic stewardship in hospital settings.