4. Immune System and Defence Forces
• Pathogens - Enemies
• Immune response - Operation of War.
• Site of infection - War field.
• Bone marrow - Army head quarter.
• Thymus, Spleen, Lymph node - Training Centres.
• Immune cells - Soldiers.
• Antigen Presenting Cells - Sentries.
• Antibodies, Complements - Arrows and bullets.
5. Major Targets of Defence System
Bacteria
Viruses
Fungi
Protozoans
Helminth Worms
Worn out Cells – RBC
Tissue debris – Injury
Cancer Cells
7. Layered Defence
Physical Barriers – Skin, Coughing, Sneezing –
first line of defense.
Innate Immunity – obtained – birth – natural
defense.
Acquired Immunity – developed – during life
Immunological memory
8. Innate Immunity
Resistance obtained – birth
Natural defense
Inherited – parents – young ones.
Non- specific.
General protective reaction – against any invasion.
Effective – wide range of infectious agents.
9. It operates through following factors
Physical and Mechanical Factors
Biochemical Factors
Cellular Factors
Genetic Factors
Body Temperature
Inflammation
Fever