This project is about further developing probe array techniques for life science applications, notably in the context of cancer research. The consortium shows the balance between experts in sensing technology as well as oncology.
IntOGen, Integrative Oncogenomics for Personal Cancer Genomeschristian.perez
IntOGen was presented September, 11th at the CSHL Meeting on Personal Genomes. The talk was given by Christian Perez-Llamas and he presented the main features of the current version and the advances of IntOGen 2.0 to store, analyze and visualize next generation sequencing data from cancer samples.
CSHL Meeting on Personal Cancer Genomes web: http://meetings.cshl.edu/meetings/person10.shtml
This project is about further developing probe array techniques for life science applications, notably in the context of cancer research. The consortium shows the balance between experts in sensing technology as well as oncology.
IntOGen, Integrative Oncogenomics for Personal Cancer Genomeschristian.perez
IntOGen was presented September, 11th at the CSHL Meeting on Personal Genomes. The talk was given by Christian Perez-Llamas and he presented the main features of the current version and the advances of IntOGen 2.0 to store, analyze and visualize next generation sequencing data from cancer samples.
CSHL Meeting on Personal Cancer Genomes web: http://meetings.cshl.edu/meetings/person10.shtml
A SuperMinds 2014 Talk by Tim Verbelen (iMinds - IBCN – UGent).
Currently Cloud Computing is a hot topic in computer science. Recently, with the rising popularity of wearable and smart devices, resources are not only clustered in datacenters, but are also present everywhere around you: Instead of a distant Cloud you are surrounded by a Fog. However, since the beginning of computer networks, people already had the vision of intelligent interconnected devices everywhere. Are we there yet, and what are the challenges still to be tackled?
Dunkin Donuts India - Event & Activation Strategy IdeaSoumitra Roy
The following is an Event and Activation Strategy idea presentation for Dunkin Donuts India made by Advertising and Public Relations students of Indian Institute of Mass Communication, New Delhi
Biofield Sciences has been developing a premedical, non invasive assessment protocol. This preventative approach has led us to imaging the human biofield, where the early warning signs of disease develop. Please visit our website www.biofieldscience.com and have a look at our new Biofield Viewer, www.biofieldviewer.com
A SuperMinds 2014 Talk by Tim Verbelen (iMinds - IBCN – UGent).
Currently Cloud Computing is a hot topic in computer science. Recently, with the rising popularity of wearable and smart devices, resources are not only clustered in datacenters, but are also present everywhere around you: Instead of a distant Cloud you are surrounded by a Fog. However, since the beginning of computer networks, people already had the vision of intelligent interconnected devices everywhere. Are we there yet, and what are the challenges still to be tackled?
Dunkin Donuts India - Event & Activation Strategy IdeaSoumitra Roy
The following is an Event and Activation Strategy idea presentation for Dunkin Donuts India made by Advertising and Public Relations students of Indian Institute of Mass Communication, New Delhi
Biofield Sciences has been developing a premedical, non invasive assessment protocol. This preventative approach has led us to imaging the human biofield, where the early warning signs of disease develop. Please visit our website www.biofieldscience.com and have a look at our new Biofield Viewer, www.biofieldviewer.com
The revolution of nanotechnology in molecular biology gives an opportunity to detect and manipulate atoms and molecules at the molecular and cellular level.
Medical and environmental diagnosis is benefiting from the recent efforts in device miniaturization and nanobiotechnology. Small devices able to analyze minute amounts of patient samples have gone their way in laboratories. Those devices are called "lab on a chip" or "µTAS" (micro total analysis system). Their purpose is a faster and easier detection of cancer markers, pathogens, bacteria, etc ... for healthcare, food analysis and the overall environmental quality. Despite their high potential value, most of designed and fabricated devices are still at the research level and remain as "chips in the lab". This talk will go over the current trends in lab on a chip with a focus on possible blocking agents that prevent them to spread in the wild.
Is the increasing availability of automated image analysis a possibility to strengthen the application of diffusion-MRI as a biometric parameter, and to enhance the future of image biobanks? Or is this evolution threatening the position of radiologists as medical doctors. Is a redefinition of radiologist as computer technicians inevitable?
Picturing Science: An overview of Imaging TechnologiesDr. Sima Salahshor
In the past decades imaging technologies are increasingly used to model the dynamics and structure of biological systems. Biomedical imaging is now an integral part of biological and medical sciences and is used in both clinical practice and research. In this session some of the latest imaging technologies were reviewed.
Dear B.Sc MIT Students,
Attached is an essential document featuring comprehensive Questions & Answers for Nuclear medicine 3 marks questions and answers. We encourage you to utilize this resource to deepen your understanding and excel in your studies. Wishing you all the success in your academic endeavors and future careers.
Best regards,
Start-ups are major engines of economic development, yet they often lack research capacity to solve their key technical innovation challenges. Discover how iMinds arms digital start-ups with the “R” in the R&D equation.
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 4. In this session, we will cover Test Manager overview along with SAP heatmap.
The UiPath Test Manager overview with SAP heatmap webinar offers a concise yet comprehensive exploration of the role of a Test Manager within SAP environments, coupled with the utilization of heatmaps for effective testing strategies.
Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
What will you get from this session?
1. Insights into SAP testing best practices
2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
Topics covered:
Execution from the test manager
Orchestrator execution result
Defect reporting
SAP heatmap example with demo
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Encryption in Microsoft 365 - ExpertsLive Netherlands 2024Albert Hoitingh
In this session I delve into the encryption technology used in Microsoft 365 and Microsoft Purview. Including the concepts of Customer Key and Double Key Encryption.
PHP Frameworks: I want to break free (IPC Berlin 2024)Ralf Eggert
In this presentation, we examine the challenges and limitations of relying too heavily on PHP frameworks in web development. We discuss the history of PHP and its frameworks to understand how this dependence has evolved. The focus will be on providing concrete tips and strategies to reduce reliance on these frameworks, based on real-world examples and practical considerations. The goal is to equip developers with the skills and knowledge to create more flexible and future-proof web applications. We'll explore the importance of maintaining autonomy in a rapidly changing tech landscape and how to make informed decisions in PHP development.
This talk is aimed at encouraging a more independent approach to using PHP frameworks, moving towards a more flexible and future-proof approach to PHP development.
Welocme to ViralQR, your best QR code generator.ViralQR
Welcome to ViralQR, your best QR code generator available on the market!
At ViralQR, we design static and dynamic QR codes. Our mission is to make business operations easier and customer engagement more powerful through the use of QR technology. Be it a small-scale business or a huge enterprise, our easy-to-use platform provides multiple choices that can be tailored according to your company's branding and marketing strategies.
Our Vision
We are here to make the process of creating QR codes easy and smooth, thus enhancing customer interaction and making business more fluid. We very strongly believe in the ability of QR codes to change the world for businesses in their interaction with customers and are set on making that technology accessible and usable far and wide.
Our Achievements
Ever since its inception, we have successfully served many clients by offering QR codes in their marketing, service delivery, and collection of feedback across various industries. Our platform has been recognized for its ease of use and amazing features, which helped a business to make QR codes.
Our Services
At ViralQR, here is a comprehensive suite of services that caters to your very needs:
Static QR Codes: Create free static QR codes. These QR codes are able to store significant information such as URLs, vCards, plain text, emails and SMS, Wi-Fi credentials, and Bitcoin addresses.
Dynamic QR codes: These also have all the advanced features but are subscription-based. They can directly link to PDF files, images, micro-landing pages, social accounts, review forms, business pages, and applications. In addition, they can be branded with CTAs, frames, patterns, colors, and logos to enhance your branding.
Pricing and Packages
Additionally, there is a 14-day free offer to ViralQR, which is an exceptional opportunity for new users to take a feel of this platform. One can easily subscribe from there and experience the full dynamic of using QR codes. The subscription plans are not only meant for business; they are priced very flexibly so that literally every business could afford to benefit from our service.
Why choose us?
ViralQR will provide services for marketing, advertising, catering, retail, and the like. The QR codes can be posted on fliers, packaging, merchandise, and banners, as well as to substitute for cash and cards in a restaurant or coffee shop. With QR codes integrated into your business, improve customer engagement and streamline operations.
Comprehensive Analytics
Subscribers of ViralQR receive detailed analytics and tracking tools in light of having a view of the core values of QR code performance. Our analytics dashboard shows aggregate views and unique views, as well as detailed information about each impression, including time, device, browser, and estimated location by city and country.
So, thank you for choosing ViralQR; we have an offer of nothing but the best in terms of QR code services to meet business diversity!
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
Elevating Tactical DDD Patterns Through Object CalisthenicsDorra BARTAGUIZ
After immersing yourself in the blue book and its red counterpart, attending DDD-focused conferences, and applying tactical patterns, you're left with a crucial question: How do I ensure my design is effective? Tactical patterns within Domain-Driven Design (DDD) serve as guiding principles for creating clear and manageable domain models. However, achieving success with these patterns requires additional guidance. Interestingly, we've observed that a set of constraints initially designed for training purposes remarkably aligns with effective pattern implementation, offering a more ‘mechanical’ approach. Let's explore together how Object Calisthenics can elevate the design of your tactical DDD patterns, offering concrete help for those venturing into DDD for the first time!
Securing your Kubernetes cluster_ a step-by-step guide to success !KatiaHIMEUR1
Today, after several years of existence, an extremely active community and an ultra-dynamic ecosystem, Kubernetes has established itself as the de facto standard in container orchestration. Thanks to a wide range of managed services, it has never been so easy to set up a ready-to-use Kubernetes cluster.
However, this ease of use means that the subject of security in Kubernetes is often left for later, or even neglected. This exposes companies to significant risks.
In this talk, I'll show you step-by-step how to secure your Kubernetes cluster for greater peace of mind and reliability.
5. The evolution of bio-imaging
Weissleder and Pittet. Imaging in the era of molecular oncology. Nature 2008
6. Microscopy & Optical imaging
The human eye can focus from 20cm to
infinity control illumination and resolve to
±100 m however it can’t magnify
The Nimrud Lens
Babylon750-710 BC
The British Museum
7. Molecular Biology
Genomics
Proteomics
Metabolomics
The ‘omics’ is very trendy today in daily science
8. Molecular Biology
Translation
DNA mRNA Proteins Metabolites
±25000 genes ±500000 Nx107 Nx106
Transcription
Effect of the environment (life style)
Genomics
Gene
≠
Proteomics Blueprint
Metabolomics
9. The evolution of bio-imaging
Weissleder and Pittet. Imaging in the era of molecular oncology. Nature 2008
10. The Bridge
Small Animal Imaging
Molecular Biology Medical Imaging
11. The evolution of bio-imaging
Weissleder and Pittet. Imaging in the era of molecular oncology. Nature 2008
12. In the beginning there was …
Wilhelm Röntgen 22 December 1895 23 January 1896
Nobel Prize Physics 1901 Hand of Anna Berthe Hand of Albert von Kölliker,
Discovery of X-rays a famous anatomist
13. … the first medical image ?
The hand of a 12-year-old boy who had shot
himself one month before his hand was
examined by x-rays in 1896 at at Columbia
University.
14. … the first medical image ?
Find Fight Follow
Up
Diagnosis Treatment Follow-up
The hand of a 12-year-old boy who had shot
himself one month before his hand was
examined by x-rays in 1896 at at Columbia
University.
15. The medical imaging timeline
Weissleder and Pittet. Imaging in the era of molecular oncology. Nature 2008
16. The medical imaging timeline
1900 1910 1920 1930 1940 1950 1960 1970 1980 1990 2000 2010
X-ray CT
MRI
Fiber optics
SPECT
PET
17. The medical imaging timeline
1900 1910 1920 1930 1940 1950 1960 1970 1980 1990 2000 2010
X-ray CT
MRI
Fiber optics
SPECT
Find Fight Follow
Up PET
Diagnosis Treatment Follow-up
28. Imaging Analogue: Functional imaging
Carrier or Agent Label
Specific moiety Moiety for detection
Moiety for localization of specific process Moiety for imaging signal
37. The role of molecular biology
Genomics Cancer
Proteomics Alzheimer
Metabolomics CAD
38. Biomarkers
The FDA defines a biomarker as, "A characteristic that is
objectively measured and evaluated as an indicator of normal
biologic processes, pathogenic processes, or pharmacologic
responses to a therapeutic intervention".
Agent
Optical label (in vitro)
Radioactive label (in vivo) Target
41. MICAD
List contains today 5076 items !!
Probably not complete
Only 236 FDA Approved
From which 123 Discontinued
Thus 113 still available
47 SPECT and PET Tracers
3357 SPECT and PET tracers
(66%)
47 FDA Approved
42. Biomarker development
Multi-disciplinary
R. Weissleder, B.D. Ross, A. Rehemtulla, S.G. Gambhir (Eds.), Molecular Imaging: Principles and Practice.
43. Biomarker development
In-vitro
In-vivo
R. Weissleder, B.D. Ross, A. Rehemtulla, S.G. Gambhir (Eds.), Molecular Imaging: Principles and Practice.
44. Biomarker development
Cellular / Molecular level Cell culture
Molecular Biology
In-vitro
Preclinical imaging
Clinical imaging
In-vivo
Human Small animal
45. Small animal imaging
70 kg 250 g
280x smaller in volume
±6.5 times smaller / direction
1 mm 150 µm
46. Small animal imaging
70 kg 20 g
3500x smaller in volume
±15 times smaller / direction
1 mm 66 µm
49. Small animal imaging
Disease Progression
imaging
quantitative parameters
therapy
Response to Therapy
50. Small animal imaging
Modality Study time Resolution Intrinsic Probe Dynamic Radiation Cost
Contrast Sensitivity Imaging Dose
SPECT 30-90 min 0.5-2 mm None <pM Yes 10-100cGy 700K
PET 5-60 min 1-2 mm None <pM Yes 10-100cGy 700K
MRI ±60 min <100 µm High µM - mM Yes - 1M
CT 10-15 min <200 µm Low mM No 10-20cGy 350K
US ±60 min <100 µm Low ? Yes - 200K
BLI ±5 min ±1 cm None nM Yes - 250K
FLI ±5 min <5 mm Variable nM No - 150K
NIR ±10 min <5 mm None pM No - 250K
Multi-modality imaging
