This document provides an overview of imaging of the wrist joint. It begins with an introduction to the anatomy of the wrist joint and the role of x-ray and MRI in evaluation. Specific anatomical structures are then described such as the carpal arcs, axes, angles, ligaments and neurovascular structures. Common pathologies are discussed including tears of the triangular fibrocartilage complex (TFCC), scapholunate dissociation, lunate dislocations, and Kienbock's disease. Imaging appearances of these conditions on x-ray, ultrasound and MRI are presented. Other topics covered include ulnar variance, carpal tunnel syndrome, Guyon's canal syndrome, and intersection syndromes.
Anatomy and imaging of wrist joint (MRI AND XRAY)Kajal Jha
Anatomy and imaging of wrist joint (xray and MRI).
this ppt was made as the class presentation by Kajal Jha as the part of the course of BSC MIT at BPKIHS,Dharan . It covers the part of syllabus of third year of BSC MIT of this institution.
Anatomy and imaging of wrist joint (MRI AND XRAY)Kajal Jha
Anatomy and imaging of wrist joint (xray and MRI).
this ppt was made as the class presentation by Kajal Jha as the part of the course of BSC MIT at BPKIHS,Dharan . It covers the part of syllabus of third year of BSC MIT of this institution.
MRI ANATOMY OF WRIST AND ELBOW ; special emphasis on TFCC, planning of wrist and elbow mri, intrinsic and extrinsic ligaments, compartments of wrist, neurovascular anatomy of elbow and wrist,
71-Dr Ahmed Esawy imaging oral board of MRI hip joint part IAHMED ESAWY
71-Dr Ahmed Esawy imaging oral board of MRI hip joint part I
Clicking hip
Labral tears
Osteoid osteoma
Avascular necrosis
Transient bone marrow oedema
Synovial proliferative disorder
Osteoarthritis
Bursitis
Osteoarthritis
Occult fracture
congenital hip dislocation
congenital hip dysplasia
72-Dr Ahmed Esawy imaging oral board of MRI hip joint part IIAHMED ESAWY
72-Dr Ahmed Esawy imaging oral board of MRI hip joint part II
Clicking hip
Labral tears
Osteoid osteoma
Avascular necrosis
Transient bone marrow oedema
Synovial proliferative disorder
Osteoarthritis
Bursitis
Osteoarthritis
Occult fracture
congenital hip dislocation
congenital hip dysplasia
Radiological anatomy of Knee joint.pptxAlauddin Md
Radiological anatomy of Knee joint , this is prepared by me for my presentation at department. if someone is benefitted that will be a great pleasure for me.
MRI ANATOMY OF WRIST AND ELBOW ; special emphasis on TFCC, planning of wrist and elbow mri, intrinsic and extrinsic ligaments, compartments of wrist, neurovascular anatomy of elbow and wrist,
71-Dr Ahmed Esawy imaging oral board of MRI hip joint part IAHMED ESAWY
71-Dr Ahmed Esawy imaging oral board of MRI hip joint part I
Clicking hip
Labral tears
Osteoid osteoma
Avascular necrosis
Transient bone marrow oedema
Synovial proliferative disorder
Osteoarthritis
Bursitis
Osteoarthritis
Occult fracture
congenital hip dislocation
congenital hip dysplasia
72-Dr Ahmed Esawy imaging oral board of MRI hip joint part IIAHMED ESAWY
72-Dr Ahmed Esawy imaging oral board of MRI hip joint part II
Clicking hip
Labral tears
Osteoid osteoma
Avascular necrosis
Transient bone marrow oedema
Synovial proliferative disorder
Osteoarthritis
Bursitis
Osteoarthritis
Occult fracture
congenital hip dislocation
congenital hip dysplasia
Radiological anatomy of Knee joint.pptxAlauddin Md
Radiological anatomy of Knee joint , this is prepared by me for my presentation at department. if someone is benefitted that will be a great pleasure for me.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
2. Introduction
• This joint is a complex joint in upper limb
• Consists of articulations of Radius, ulna,
carpus and carpo-metacarpal bones
• To evaluate and interpret wrist images one
should be fully aware of the anatomy
• X ray serves as basic tool while MRI serves to
answer the issues of soft tissues
3. Anatomy
• Wrist joint is formed by
Distal radio-ulnar joint,
Radio-carpal and Mid-
carpal joint
• Sigmoid notch of radius
articulates with ulna
5. Parallelism and symmetry
• Joint spaces of wrist joint
are more or less
symmetrical
• Average width of joint
spaces are 2mm or less
• Capitato-lunate serves
as standard space to
which others should be
compared.
6. Carpal arcs
• Three arcs should be
drawn
• 1st is formed by
convexities of Scaphoid,
lunate and Triquitrum
bones
• 2nd is formed by inner
concavities of same bones
• 3rd is formed by proximal
curvature of Capitate and
hamate.
7. Asymmetry
• Any asymmetry in the
joint space and loss of
parallelism points that
some disruption has
occurred
• Depending on which
arch or which joint
space is widened,
pathology lies in the
same compartment
9. Angles and Axes of Carpals
• Scaphoid axis : is formed
by proximal and distal
poles
• Lunate axis : is drawn
perpendicular to proximal
convex and distal concave
surface
• Capitato-lunate angle : >
30 is abnormal
• Scapho-lunate angle: 30-
60 is normal; 60-80 is
questionable and > 80 is
abnormal
11. Flexor retinaculum
• Is a rectangular fibrous
band and forms roof of
carpal tunnel
• Radially attached to
ridge of trapezium and
on ulnar aspect to hook
of hamate
• On ulnar aspect it forms
Guyon canal
13. Guyon’s canal
• Is a fibro-osseous
tunnel that contains
ulnar neuro-vascular
bundle
• Landmarks are deep to
FCU, Lateral to Pisiform
and at the hook of
hamate
14. Extensor Tendons
• On dorsal aspect,
tendons are divided
into 6 compartments
• Lister tubercle is
important landmark
that separates II and III
compartment.
15.
16. Triangular Fibro-Cartilage complex
• It is a complex structure
has various parts :
Triangular fibro-
cartilage ; Radio-ulnar ;
ulno-carpal; Meniscal
homologue; ECU
tendon and ulnar
collateral ligament.
21. Inter-carpal ligaments
• These are stabilizers of the wrist joint and are
divided into extrinsic and intrinsic parts.
• Intrinsic : Scapho-lunate, Luno-triquetral are
important ones .
TFCC.
• Extrinsic: volar, Dorsal, RCL and UCL
22. Inter-carpal ligaments
• The two important
ligaments are in the
proximal row : scapho-
lunate and luno-
triquitrum.
• The first one is
pyramidal and latter is
horse shoe in shape
24. TFCC Tear
• It can be traumatic in
young in radial end and
degenerative in elderly at
ulnar end
• Presents with ulnar side
wrist pain
• Seen as fluid intensity
signal along the ulna
• Discontinuity of complex
is seen on MR
arthrogram.
27. Palmer classification
• class 1
a) central perforation
b) Ulnar avulsion with or
without ulnar fracture
c) Avulsion of Ulno-
triquetral and ulno-
ilunate ligament
d) Radial avulsion of TFCC
• Class 2
a) TFCC wear with thinning
without perforation
b) TFCC wear with
ulnar/lunate/triquetral
chondromalacia
c) TFCC perforation with
chondromalacia
d) Luno-triquetral perf with
2a/2b or 2c
e) Any of above with ulno-
carpal arthritis
28. Scapho-lunate dissociation
• Is aka rotatory
subluxation of scaphoid.
• Refers to abnormal
orientation of scaphoid
and lunate and is due to
injury to the scapho-
lunate ligament
• Relative flexion of
scaphoid with relative
extension of lunate is
typical pattern
• On x ray widened
Scapho-lunate interval
of >4mm is seen
• Increase in Scapho-
lunate angle >60 degree
• On MRI examination, It
is seen as discontinuity
of the Scapho-lunate
ligament along with
joint effusion.
31. Lunate Dislocations
• These are uncommon traumatic wrist
injuries .
• Lunate is displaced and rotated volarly.
• Occurs due to fall on out-stretched hand.
• Lunate shows “Piece of Pie sign”
• Rest of the bones are well aligned with
maintained symmetry.
33. Peri-lunate dislocation
• Are potentially closed wrist injuries and
involve the carpus relative to lunate
• involves scapho-lunate and Luno-
triquetral ligaments
• In this pathology, the Capitate (apple)
doesn’t sit in the concavity of Lunate
(Cup)
34.
35. Dorsal and Volar intercalated
segment instability
• DISI is the form of
instability involving
wrist joint in which
Lunate is displaced
dorsally.
• Disruption of the
scapho-lunate ligament
• Due to wrist trauma
• SL angle of >60 degree
• CL angle >30 degree
• VISI is less common
in which lunate is
displaced palmarly
• Ligament injured is
Luno-triquetral
ligament
• SL <30 degrees
• CL >30 degree
38. Ulnar variance
• It is defined as the relative length of distal end of ulna
wrt radius
• If ulna is shorter than radius it is called Negative ulnar
variance
• If ulna is longer than radius it is called positive ulnar
variance
• If both are equal it is called neutral variance
• On radiographs Positive variance is when the level of
the ulna is >2.5 mm beyond the radius margin at the
distal radio-ulnar joint and negative variance is when
the ulna is ≤2.5 mm than the radius at the DRUJ
40. Ulnar impaction syndrome
• Occurs in association with
positive ulnar variance
• May occur with distal
radial fracture
• Consequent bone signal
changes are seen in distal
ulna, radial side of
triquetrum and ulnar side
of lunate
• TFCC and luno-triquetrum
tear is seen on MRI
42. Ulnar impingement syndrome
• Occurs in association with
Negative ulnar variance
• shortened distal ulna
results in contraction of
the extensor pollicis
brevis, abductor pollicis
longus, and pronator
quadratus muscles which
prevents normal
buttressing of the
radioulnar joint.
• Seen as edema where
ulna converges on radius
44. AVN of Scaphoid bone
• Trauma of scaphoid
bone leads to AVN
• It has peculiar blood
supply where in
proximal pole receives
blood supply in
retrograde fashion
• It mnifests as sclerosis
of bone on wrist
radiographs
46. Kienbock disease
• Is associated with negative ulnar variance
together with a susceptible blood vessel
• Is defined as osteonecrosis of the lunate
where cortical blood supply is compromised
and results in infarction of the bone with
surrounding hyperemia
• Sclerosis with negative ulnar variance is seen
• Bone signal changes are seen along the central
and radial aspect of lunate
48. Stahl classification of Kienbock disease
• stage I: normal radiograph
• stage II: increased radio density of the lunate
with possible decrease of lunate height on the
radial side only
• stage III
– IIIa: lunate collapse, no scaphoid rotation
– IIIb: lunate collapse, fixed scaphoid rotation
• stage IV: degenerative changes around lunate
50. Carpal coalition
• Refers to failure of separation of two or more
carpal bones
• Lunate and triquetrum are most common
• It may be osseous, cartilaginous or fibrous
• Associated with Holt oram, turner syndrome
etc
52. Carpal Tunnel Syndrome
• Results from the compression of Median Nerve in carpal tunnel
• Nocturnal ascending pain emanating from the wrist, is typical
• sensory symptoms affect the first three digits and, depending on
innervation patterns, the radial aspect of the fourth digit
• Positive Tinel test: paresthesias elicited by tapping the median
nerve at the wrist
• Occurs due to
mechanical overuse (considered the most common association)
osteoarthritis
trauma
acromegaly
• Ganglion cysts, primary nerve sheath tumors
synovial hypertrophy in rheumatoid arthritis
53. USG CTS
criteria
• Palmar bowing of Flexor
retinaculum of >2mm
• Flattening of nerve distally
with increased thickness
proximally
• Normal Cross section area is
9-11mm sq
• Difference of > 2mm sq at
CT and pronator quadratus
has high sensitivity
Image
56. MRI for CTS
• In carpal tunnel syndrome, MRI can demonstrate
palmar bowing of the flexor retinaculum,
enlargement of the median nerve at the level of
the pisiform, and flattening of the median nerve
at the level of the hook of hamate.
• Other signs are edema or loss of fat within the
carpal tunnel, and increased size or edema of the
nerve on fluid-sensitive sequences, and, in some
cases, contrast enhancement of the nerve
60. Fibrolipomatous hamartoma of MN
• It is a benign neoplasm
of median nerve
• Proliferation of fibro-
adipose tissue of sheath
• Imaging features are co-
axial cable like
appearance on axial and
spaghetti like on
coronal images
61.
62. Guyon’s canal syndrome
• Results from compression
of ulnar nerve.
• Hook of hamate fracture,
Ganglion cyst are its
causes.
• On x ray hook of hamate
fracture is seen.
• On USG ganglion cyst,
lipoma or ulnar artery
thrombus is seen and on
MRI these findings are
seen with better accuracy
63. De Quervain TS
• Aka washerwoman’s
sprain
• Occurs due to
inflammation of EPB
and APL tendons
• On USG Thickening of
tendons with fluid in
extensor compartment
and increased flow on
CDI in peri-tendonous
region
64.
65. MRI
• More sensitive and
specific
• Increased fluid in
tendon sheath
• Thickened edematous
retinaculum with peri
tendenous edema
• Sometimes features of
tendonosis are also
seen
66. Proximal intersection syndrome
• Is overuse tenosynovitis around the
intersection of 1st and 2nd compartment
extensor tendons
• Seen in weight lifters, skiers etc
• Fluid is seen within the involved tendons with
loss of hyper echoic plane between the
tendon compartments
• On MRI peri tendenous edema is noted 4cm
proximal to lister’s tubercle
68. Distal intersection syndrome
• Relates to teno-synovitis of EPL tendon where
it crosses the ECRB and ECRL tendon
• Crossover is located just distal to lister’s
tubercle
• Over us, trauma and RA are etiologic factors
• Edema is noted in peri-tendenous region at
intersection point
70. Ganglion cyst
• is a non malignant
cystic mass and result
from myxoid
degenration of
connective tissue
assoiated with joint
capsule and tendon
sheath
• Seen as anechoic cyst
with PAE on USG and
cystic signal on MRI
71.
72. Value of axial and coronal images
Axial
• Distal RU joint
• Carpal tunnel and contents
• Flexor and extensor tendons
• Ulnar nerve and median
nerve pathologies
Coronal
• TFCC
• Ulnar Variance
• Scapho-lunate and Luno-
triquetral ligaments
• Fractures
• AVN
• Arthropathies
73. Summary
History and clinical findings should be available
Assess the congruity of bones on bones, Look for
any asymmetry
Look for ulnar variance
Look for any bone marrow edema/effusion
Asses inter-carpal ligaments and TFCC
Look carefully for any pathology of
carpal/Guyon’s canal
Findings should be noted to reach to a specific
diagnosis