If the characteristic followed in the pedigree is X-linked recessive allele, what is II-I\'s genotype? a. Hemizygous for a dominant allele Hemizygous for a recessive allele Definitely heterozygous Solution 34. Answer: C. Definitely heterozygous two copies of a disease allele on the X chromosome are required for an individual with two X chromosomes (a female) to be affected with an X-linked recessive disease. Affected males transmit the disease allele to all of their daughters, who are then carriers, but to none of their sons..