IC-SDV 2019: BizInt

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New reports and visualizations
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Patents & IP Sequences | Clinical Trials | Drug Pipelines
IC-SDV 2019 – Nice, France
8 April, 2019
John Willmore, Product Development

© 2019 BizInt Solutions, Inc | www.bizint.com 2
Reports integrating data from multiple sources

choosing content by rules…

linking unique content…

…and summarizing data elements.

Piano Chart (from clinical trials data)

Event timeline (from clinical trials data)

Structure oriented “Index of Hit Structures”
Each hit substance
identified
Links to references
for each structure
Multiple images
(continuation)
or mixtures
Structures with
annotations

Piano Chart (from drug pipeline data)
Merkel cell carcinoma (MCC) pipeline: Phase for MCC and type of molecule
Biological Testing
Merkel cell carcinoma
therapies
Vironika
Preclinical
CK-301
TG Therapeutics
ETBX-051
NantWorks
ETBX-061
NantWorks
ipilimumab
Bristol-Myers Squibb Co
LTvax
APCure
Merkel cell polyomavirus
inhibitors
Vironika
Phase I
BGB-A317
Celgene
ID-G100
Immune Design
pasireotide
Novartis
SIRPa-Fc
Trillium Therapeutics
utomilumab
Pfizer
Phase II
ALT 803
Altor BioScience Corporation
cabozantinib S-malate
Exelixis
CST-101
NantWorks
F16-IL2
Philogen
MCPyV vaccine
Fred Hutchinson Cancer
Research Center
nivolumab
Ono Pharmaceutical Co Ltd
pazopanib
GlaxoSmithKline plc
pembrolizumab
Merck & Co
PEN-221
Tarveda Therapeutics
sapanisertib
Intellikine
talimogene laherparepvec
BioVex Inc
tavokinogene telsaplasmid
OncoSec Medical
Launched
avelumab
Merck KGaA
Discontinued
lorvotuzumab mertansine
ImmunoGen
No Development Reported
ATN-161
Attenuon
tivantinib
ArQule
Type of molecule
Antibody
Biological, other
Cell & gene therapy
Protein & peptide
Small molecule therapeutic
Vaccine
Drugs color-coded by a
chosen field
Labeled by drug name and
a chosen field
Option for hyperlink
to pipeline record
Each column contains
the drugs in that phase

amatuximab
ARGX-110
atezolizumab
BGB-A317
brentuximab vedotin
CAT-5001
CK-301
durvalumab
durvalumab + tremelimumab
ipilimumab
nivolumab
pembrolizumab
tremelimumab
YSCMA
CRS-207
galinpepimut-S
JTCR-016
K562/GM-CSF
MesoPher
TroVax
WT1 vaccine
aglatimagene besadenovec
anti-mesothelin CAR
gene therapy
MesoCART
miR-15/16 mimics
MTG-201
MTG-202
GL-ONC1
HSV-1716
MV-NIS
MV-NIS therapy
ONCOS-102
CBP-501
FP-1039
LMB-100
NGR-hTNF
pegargiminase
AEOL-10150
AZD-4547
BNC-105P
carfilzomib
CB-839
dasatinib
defactinib
gemcitabine prodrug
imatinib
lurbinectedin
LY-3023414
Minerval
napabucasin
nintedanib
pemetrexed
pevonedistat
porfimer sodium
raltitrexed
roniciclib
sunitinib
tazemetostat
trabectedin
trametinib
TRC-102
vinorelbine
zoledronic acid
Small molecules
Cell/Gene therapies
Antibodies
Peptides/Proteins
Cancer vaccines
Oncolytic viruses
Mesothelioma – Bulls-Eye created for PowerPoint
Marketed
Phase 3
Phase 2
Phase 1

Patent Databases
Provide data on patents filed worldwide
• STN – Classic (including STNext) & New STN
• Questel Orbit.com (including FULLPAT)
• Minesoft PatBase
• Innovation, Cortellis IP, Integrity Patents
• LexisNexis TotalPatent
• GQ LifeSciences LifeQuest

IP Sequence Databases
Provide data on sequences filed in patents
• GenomeQuest (Geneseq, GQ-PAT)
• STN (USGENE, DGENE, PCTGEN

Literature Databases
Provide data on technical and scientific publications
• Biomedical (Embase, Biosis, Medline)
• Scientific (SciSearch, Chemical Abstracts,
PQSciTech, etc)
• Technical (INSPEC, RAPRA, GEOREF, etc.)
• Hosts: STN (Classic & New),
ProQuest Dialog, Ovid, PubMed

• Citeline Pharmaprojects
• IMS R&D Focus
• Adis R&D Insight
• Clarivate Cortellis
• Clarivate Integrity
• And, support for Infodesk PipelinePlus
Drug Pipeline Databases
Provide data on drugs in development worldwide

Clinical Trials Databases
Provide data on drug trials worldwide
• Commercial: Citeline TrialTrove
Adis Clinical Trials Insight
Cortellis Trials Intelligence
• Public: ClinicalTrials.gov, WHO ICTRP,
EU Clinical Trials (EudraCT)
• Biomedical literature on Ovid, PubMed,
ProQuest Dialog, STN

VantagePoint – Smart Charts Edition (VP-SCE)
• Customized version of VantagePoint
software from Search Technology.
• Clean-up, filter and visualize data
from BizInt Smart Charts reports.
• Version 11 just released –
new ribbon interface, more
powerful list cleanup, etc.

Enhanced literature support coming soon
• Identify Common Document tool
• Additional fields for analysis (year, first author,
author/affiliation linkage)
• Additional databases on STN
• Additional databases on ProQuest Dialog
• Literature support in all products

Link from DOI’s to articles

Support for Reaxys coming soon
STNextComing Soon!

Support for CAS BioSequences coming soon
• Adding support for CAS BioSequence data on
Aptean GenomeQuest, including additional CAS
sequence indexing fields
• Adding support for CAS BioSequence data on STN
(via the BLAST tool)
• Investigating support for HITSEQ reports

• Five customers share their experiences on
Tuesday afternoon and Wednesday morning.
• Keynotes and workshops on Wednesday.
• Still time to register!
• See us or go to bizint.com/avm for more details

Visit us in the exhibit
hall to learn more!
www.bizint.comdoxifun.com/puppies
Patents & IP Sequences | Clinical Trials | Drug Pipelines

IC-SDV 2019: BizInt

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