This document discusses the experiences of an Indonesian company in developing and commercializing ECVT and ECCT technologies for cancer diagnosis and therapy. It provides an overview of the company's milestones in developing electrical capacitance volume tomography (ECVT) and electro-capacitive cancer therapy (ECCT) technologies. Key applications of ECVT discussed include industrial process imaging, brain imaging, and breast cancer scanning. ECCT is presented as a non-contact cancer therapy approach. Comparisons of ECVT and other imaging modalities for various applications are also provided.

1. BUILDING TECHNOLOGY
COMPANY IN INDONESIA
EXPERIENCES IN DEVELOPINGAND
COMMERCIALIZING ECVT& ECCTTECHNOLOGIES
FORCANCER DIAGNOSIS &THERAPY
DEN HAAG,THE NETHERLANDS
14 SEPT2013
WARSITO PTARUNO
TheEngineofTomorrow
CTECH LABS
EDWARTECHNOLOGY
CTECH LABS
EDWARTECHNOLOGY

2. TERMINOLOGI
ECVT (ELECTRICAL
CAPACITANCEVOLUME
TOMOGRAPHY):
4DTOMOGRAPHY UNTUK
APLIKASI INDUSTRI DAN
MEDIS
ECCT (ELECTRO-
CAPACITIVECANCER
THERAPY):
Terapi Kanker berbasis
gelombang listrik bertenaga
sangat lemah dalam bentuk
peralatan baju listrik

3. The MilestonesBSResearchstart:USSensorfor
3-phasereactorinstrumentation
World’sFirstUSTomography
for3-PhaseReactorImaging
World’sFirstUSTechniquefor3-
PhaseReactorMeasurement
CapacitiveTomographyforreal
time3-PhaseReactorImaging
ImageReconstructionAlgorithm
forCapacitiveTomography
PatentGranted
4DElectricalCapacitance
VolumeTomography
(ECVT)PatentGranted
FirstGenerationECVTSystem
(DAS);
SONACTXforCNGCylinder
ScannerDeveloped
2.5GenerationECVTSystem
(DAS)
World’sFirst4DECVTBrain
ActivityScanner
ElectroCapacitiveCancer
Therapy(ECCT)Invented;
World’sFirstECVTBreast
CancerScanner
Shizuoka University, JPN Ohio State University, US
CTECH Laboratories The Center forTomography Research
EDWARTECHNOLOGY
Technology Users: Ohio State University (USA), NASA, Univ. of Cambridge
(UK); B&W (USA); US DoE; BBG (INA), National Univ. of Malaysia,Univ. of Malaya
(MLY), KAU (KSA)
1992 1997 1999 2001 2003 2006 2008 2009 2010 2012

4. PrincipleofECVT
STEP 1: Capacitance measurement
STEP 2: Reconstructing 3D permittivity distribution
E

V

V
ECVT system consists of sensor system, data acquisition system
and computer system for control, image reconstruction and display




 d
V
C
nE ˆ
PCT, WO 2006/102388 (Warsito et al.,2006)
US PTO 6577700 (Warsito & Fan,
CTECH LABS EDWAR TECHNOLOGY

5. Industrial Scale Applications
Realtime 3D (4D) image of industrial reactor
B&W Project, Akron, OH, USA
ECVT Imaging of spray column of water-solid catalysts
system I.D. = 5ft (1.65m)
CTECH LABS EDWAR TECHNOLOGY

6. ECVTApplications:ECVTvs.SuperComputerSimulation
US Dept of Energy Project on Advanced Research to Support
Development of Next-Generation Power Plants
ECVT (Real)
Super Computer (Simulation)
CTECH LABS EDWARTECHNOLOGY

7. DoEProject
Simulation
vs.
ECVT

8. ECVT Brain Function
2010—

9. FunctionalECVT
4DBrainActivity
32-electrode Brain Scanner ECVT System

11. 4DBrain
ActivityMap

12. ECVThasbeensuccessfullyappliedtomonitoractivityofhumanbrainduringdifferentstimulations.Electricalsignalsmeasuredfromcapacitanceelectrodesshowed
significantdifferenceswhenthebrainisinrestandinhightask.TheECVTgeneratesrealtimeandvolumetricimageofthehumanbrainduringtheactivity.The
systemhelpsscientiststostudythehumanbrainactivity,andpossiblydetectabnormalitiesinthehumanbrain.
Electrical
signal
monitoring of
human brain
during
different
stimulations
Snapshot of real-time volumetric images of human brain
activity during stimulations
32-electrode Brain
Scanner ECVT Sensor
4D Scanner of Human Brain ActivityWORLD’S FIRST CTECH LABS EDWARTECHNOLOGY

13. ECVT vs. PET-CTECVT vs. MRI

14. 12/3/13
19/3/13
CASE: AMNESIA
Kaki lumpuh,
didorong dengan
kursi roda,
komunikasi sedikit
masih bisa; MRI tak
terdeteksi kelainan.
CASE: AMNESIA
Kaki sedikit membaik,
komunikasi sama-
sekali hampir ‘blank’.
Fungsi motorik
lemah
Fungsi Bahasa
lemah
CASE: Amnesia
MRI (3/3/13):
Tak terdeteksi abnormalitas

15. ECVT BreastCancer
2011—

16. ECVTforBreastScanner CTECH LABS EDWAR TECHNOLOGY

17. WORLD’S FIRST
4D BREAST CANCER SCANNER

18. ECVT
ECVT
BenignTumor
Malignant Cancer
Mammography
Mammography

19. MRI 3T
MRI 3T
A. Breast with early cancerous mass
development
B. Breast with significant cancerous mass
C. Normal Breast
CTECH LABS EDWAR TECHNOLOGY

20. ECVTvs.
Mammography
(MalignantCancers)

21. ECVTvs.
Mammography
(BenignTumors)

22. ComparisonsofPET-CT
ImageandECVTImageof
BreastCancer
ECVT Image
PET-CT Image
CTECH LABS EDWAR TECHNOLOGY

23. ECCT
ElectroCapacitiveCancerTherapy
2010–

24. ECCT(Electro-CapacitiveCancerTherapy):
ConvertingPoisson’sequationintofashionforcancertherapy
CTECH LABS EDWAR TECHNOLOGY

25. WhatdifferencewithKirson&PaltiMethod?
ECCT
 Capacitive
 Completely Non-contact
 Penetrating through air layers
 Low voltages (<30V)
 Good for lung and colon-rectum CA and
working to almost all type of cancers
including lymphoma and leukemia
NovaCure
 Quasi-Electrostatic (quasi-conductive)
 Using high-conductive ceramic
electrodes with direct contact to skin
 No-air layer permitted
 High voltages (>50V)
 Not possible for air-contact cancerous
mass (in fact work only to brain cancer)
NovaCure

26. Computation
FashionElectronics
ECCT
APPAREL
WIRED & COMPUTED SUIT

27. po
CTECH LABS EDWAR TECHNOLOGY
-
-
-
-
-
-
-
+
+
+
+
+
+
+

28. Researchoneffectofelectricalfieldoncancercellgrowths
(Highvoltage,usingquasi-conductiveelectrode)
- Electrical
field
inhibiting cell
growth (A)
- Splitting cell
destroyed
under
electrical field
(B,C)
CTECH LABS EDWAR TECHNOLOGY

29. Effect of electrical
field to breast cancer
cell MCF-7
Effect of electrical
field to Fibroblast
Vero Cell
CTECH LABS EDWAR TECHNOLOGY

30. A. Before ECCTTherapy;
B. 1 Month after ECCT
Therapy;
C. 1.5 Month after ECCT
Therapy
A
B C
CTECH LABS EDWAR TECHNOLOGYProgressofBreastCancerMass
withECCTimagedbyECVT

31. BeforeTherapy
After 2 Months of ECCTTherapy (PET-CT)
After ECCTTherapy (ECVT Image)
FDG
Activities
of Breast
Cancer
IMAGE of Breast
Cancer Before and
after ECCT
Treatment

32. Innovation Thresholds:
Being able of making a thing DOES NOT guarantee a business
Basic research
& technology
development,
research project,
limited production
of highly
customized
products
Product
development
(R&D),
Manufacturing
and distribution
Activity
End user/
customer service
based business
RESEARCH PRODUCT
MANUFACTURING
BUSINESS
Free
Imagination,
Serendipity
QA & Delivery
Known Risks,
Effective Strategy,
Timely Decision
DISCIPLINEDMIND
CHALLENGINGMIND

33. Research/
Technology
Development
Cycles
Product
Development
/Production
Cycles
Product
utilization/
Business
Cycles
RESEARCH MANUFACTURING
BUSINESS/
UTILIZATION
BUILDING INNOVATION CAPACITY IN SME
EDWAR
TECHNOLOGY
CTECH
Laboratories
Open Innovation
Strategic
Partnership
Business
Alliance

34. 1. NETWORKING
1. International links to global value change
is crucial
2. Active interaction with users (industries)
to learn demand/market
2. RESOURCES:
1. State of Mind: Strong motivation
2. Basic infrastructure: Computer, internet,
workshop, access to knowledge sources such as
digital library.
3. Basic financial: salary for full-time staffs (24/7)
3. INSTITUTION
1. Institutional legal for receiving PO
International
Scientific
Forum
International
Industrial
Linkage
Basic
Infrastructure
Basic Financial
Support
Legal formal,
venture capital

35. CLOSURE
 Open innovation and strategic partnership provide benefit
for SMEs to upgrade its capacity in innovation, but the
cooperation must stem from supply and demand
relationship (win-win solution), otherwise it will not work.
 Technology development and utilization/commercialization
must continue in parallel, otherwise the innovation will not
sustain.
 Technology business requires a completely different state
of mind, i.e. taking risk, which usually researchers do not
have; researchers need partners to commercialize their
technology.
 Funding is not always an issue for a researcher to
innovate, but cooperation is.