HVP Country Node: Democratic Republic of Congo - Aimé Lumaka Zola

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Human genetics in the Democratic Republic of Congo has evolved rapidly in recent decades. Initially there were no genetic services in the country until 1966 when a laboratory was established at KUL to study Down Syndrome. Since then genetic services have expanded, including undergraduate and medical training, genetic clinics in Kinshasa and Lubumbashi, a DNA extraction facility, and the creation of the Congolese Society for Human Genetics. Current activities include clinical genetics clinics, laboratory testing for conditions like sickle cell disease and albinism, regional networking of geneticists, and ongoing research projects. Genetics has grown to address the high needs in DR Congo, such as the prevalence of sickle cell disease.

Science

HUMAN GENETICS IN DR CONGO:
A RAPIDLY EVOLVING STORY
Prof LUKUSA TSHILOBO Prosper, MD, PhD
President of the Congolese Society for Human Genetics (CoSHG)
Prof LUMAKA ZOLA Aimé, MD, PhD
Centre for Human Genetics, UNIKIN

DR Congo
• Second biggest African country: 2.345.409 km2
• The most populated French speaking country:
– ± 80.000.000 inhabitants
• Kinshasa: ± 10 millions inhabitants
• 3 main Universities and 1 Biomedical research
center

Enormous needs for genetic services
• High prevalence of sickle cell disease (SCD):
– 25-34% AS
– 2% SS new-borns
– 80% death < 5 years
• Albinism: cutaneous carcinoma in 33%
• Intellectual disability: 27 % with genetic defects

1966
Today
History of genetics in DR Congo

Prof. H Van den Bergh et al. from KUL, laboratory
and research activities (Down Syndrome)
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

No genetic service
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

Prosper Lukusa, from KU Leuven:
• Genetics back to UNIKIN
• Conferences for practitioners
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

• Undergraduate courses
1966
Today
1978
2007
2011
2013
2015
2008
2009
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• Courses for interns and professors
• Genetic clinics
1966
Today
1978
2007
2011
2013
2015
2008
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• Extension to Lubumbashi
1966
Today
1978
2007
2011
2013
2015
2008
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• Constitution of genetic team at Lubumbashi
and Kinshasa for clinic and research
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

• Implementation of DNA extraction facility
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

• Prosper Lukusa appointed as fulltime Professor
of human genetic at Kinshasa and visiting
professor at Lubumbashi
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

• Creation of the Congolese Society for Human
Genetics
• HVP country node in 2013
• 1st congress of the CoSHG
• 2nd congress of the CoSHG
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

• In and out-clinics:
– Developmental delay
– malformations
– SCD
– Albinism
– others
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

• Laboratory: molecular testing for SCD and1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

• Regional networking: constitution of network
of geneticists from French speaking countries
since 2013
1966
Today
1978
2007
2011
2013
2015
2008
2009
2010

• Research: 10 ongoing projects + publications
1966
Today
1978
2007
2011
2013
2015
2008
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2010

ЗАЯВЛЕНИЕ об отмене решения Организационного комитета по проведению предварительного голосования по кандидатурам для последующего выдвижения от Партии «ЕДИНАЯ РОССИЯ» кандидатов в депутаты Законодательного Собрания Пермского края третьего созыва об аннулировании результатов предварительного голосования по одномандатному избирательному округу № 22

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HVP Country Node: Democratic Republic of Congo - Aimé Lumaka Zola

1. HUMAN GENETICS IN DR CONGO: A RAPIDLY EVOLVING STORY Prof LUKUSA TSHILOBO Prosper, MD, PhD President of the Congolese Society for Human Genetics (CoSHG) Prof LUMAKA ZOLA Aimé, MD, PhD Centre for Human Genetics, UNIKIN

3. DR Congo • Second biggest African country: 2.345.409 km2 • The most populated French speaking country: – ± 80.000.000 inhabitants • Kinshasa: ± 10 millions inhabitants • 3 main Universities and 1 Biomedical research center

4. Enormous needs for genetic services • High prevalence of sickle cell disease (SCD): – 25-34% AS – 2% SS new-borns – 80% death < 5 years • Albinism: cutaneous carcinoma in 33% • Intellectual disability: 27 % with genetic defects

5. History of genetics in DR Congo

6. 1966 Today History of genetics in DR Congo

7. Prof. H Van den Bergh et al. from KUL, laboratory and research activities (Down Syndrome) 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

8. No genetic service 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

9. Prosper Lukusa, from KU Leuven: • Genetics back to UNIKIN • Conferences for practitioners 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

10. • Undergraduate courses 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

11. • Courses for interns and professors • Genetic clinics 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

12. • Extension to Lubumbashi 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

13. • Constitution of genetic team at Lubumbashi and Kinshasa for clinic and research 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

14. • Implementation of DNA extraction facility 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

15. • Prosper Lukusa appointed as fulltime Professor of human genetic at Kinshasa and visiting professor at Lubumbashi 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

16. • Creation of the Congolese Society for Human Genetics • HVP country node in 2013 • 1st congress of the CoSHG • 2nd congress of the CoSHG 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

17. • In and out-clinics: – Developmental delay – malformations – SCD – Albinism – others 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

18. • Laboratory: molecular testing for SCD and1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

19. • Regional networking: constitution of network of geneticists from French speaking countries since 2013 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

20. • Research: 10 ongoing projects + publications 1966 Today 1978 2007 2011 2013 2015 2008 2009 2010

21. Thank You

HVP Country Node: Democratic Republic of Congo - Aimé Lumaka Zola

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HVP Country Node: Democratic Republic of Congo - Aimé Lumaka Zola