This document provides guidance on how to select a research topic and conduct research. It outlines important steps like identifying a problem, formulating research questions, deciding if the topic is worth investigating, defining exposures and outcomes, and designing a study. Key factors for selecting a feasible topic are relevance, specificity, being analytical and original. Important sources of research questions are advisors, literature, conferences, and funded projects. When considering a topic, researchers should think about who, what, when, where, and why questions. Objectives for descriptive and analytical studies should be clearly defined. Overall, research should solve an existing problem, fill knowledge gaps, and be innovative. The process of conducting research involves framing the topic, obtaining ethics approval,