How are eukaryotic transcription regulators able to affect transcription when their binding sites are far from the promoter? (select all that apply) Group of answer choices by attracting and stabilizing the transcriptin initiation complex via binding to the mediator the looping out of the intervening DNA between their binding site and the promoter allows contact by unwinding the DNA between their binding site and the promoter by attracting RNA polymerase and modifying it before it can bind to the promoter.

1. How are eukaryotic transcription regulators able to affect transcription when their binding sites are
far from the promoter? (select all that apply)
Group of answer choices
by attracting and stabilizing the transcriptin initiation complex via binding to the mediator
the looping out of the intervening DNA between their binding site and the promoter allows contact
by unwinding the DNA between their binding site and the promoter
by attracting RNA polymerase and modifying it before it can bind to the promoter