This document discusses host-plant resistance to pathogens. It describes the different types of resistance as monogenic or polygenic. Vertical resistance is controlled by a single gene while horizontal resistance is controlled by multiple genes. The gene-for-gene hypothesis proposes that for each resistance gene in the host there is a corresponding avirulence gene in the pathogen. Elicitors are molecules associated with pathogens that can bind to plant cell receptors to trigger defense responses. Gene pyramiding involves combining resistance genes from multiple parents into an elite variety. R genes allow plants to recognize specific pathogens. Components of disease resistance include pathogen detection, signal transduction, and defense responses.

1. Host-plant
resistance
Vedant Gautam
PhD Scholar
Department of Mycology and
Plant Pathology
Banaras Hindu University,
Varanasi

2. Resistance is the ability of a host plant to resist the growth or establishment of a
pathogen.
 Many plant pathogenic microorganisms are specific to certain host plants.
 The plant species and cultivars vary widely in their capacity to resist the
establishment of a pathogen.
 When a pathogen enters the host, it must overcome several barriers before
establishing itself.
 Sometimes the host reacts to the entrance of the pathogen or alters growth of the
pathogen and thus effectively checks the establishment of the disease.
 There is great variation in the degree of resistance of a plant to a given parasite.
 This is influenced by various factors, involving the host, parasite and environment.
Disease resistance

3. Resistance to diseases is also a genetically controlled character. Plants possess two different types
of resistance :
 Monogenic- It is controlled by specific single gene. This type possesses high resistance to a
given strain or race of the pathogen but it susceptible to other races.
 Polygenic- It is controlled by many genes and is not so high but at the same time does not
easily breakdown due to the evolution of new races. This is also referred to as
durable resistance.
 Vertical resistance:- Vertical resistance is the resistance of plants against pathogens that is
controlled by a single gene. The term vertical resistance is commonly used in plant selection. It
was first used by J.E. Vander Plank in 1963 to describe single-gene resistance.
 Horizontal resistance:- Horizontal resistance is the resistance of plants against pathogens that
is controlled by many genes. It is sometimes called generalized resistance. This term also was
first used by J.E. Vander Plank in 1963. J.E. Horizontal resistance is stable and durable.
Types of resistance

4. Difference between Vertical and horizontal resistance
Horizontal resistance Vertical resistance
Multigenic Oligogenic
Race nonspecific Race specific
Durable Less durable
Quantitative resistance Qualitative resistance
Environmentally influenced Environmentally not influenced
Often effective against Often effective against biotrophs
necrotrophs Complete
Partial (r=0 to 1) (r=0 or 1)

5. Gene for gene hypothesis
 It was first proposed by Flor (1942, 1945) as the simplest explanation of the result of
studies of the inheritance of resistance and pathogenicity flax-rust host-pathogen
system, and now applies to most of the combinations.
 According to this hypothesis, “for a resistance gene in the host there is a
complementary avirulence gene in the pathogen.”
 The coexistence of host plant and pathogen side by side in nature indicate that they
have co-evolved; and changes in virulence of pathogen have been continuously
governed by the changes in host or vice versa.
 This concept has been shown to operate in many other diseases like rusts, smuts,
apple scab, late blight of potato and many other fungal , bacterial , virus and higher
parasitic plant diseases.

6. Gene for gene hypothesis
 Generally, but not always in the host, gene for resistance is dominant (R) and gene for
susceptibility is recessive (r).
 In pathogen, however, gene for avirulence that have inability to infect is dominant (A)
and for virulence it is recessive (a).
 Thus plant variety when carrying gene for resistance (R) for certain pathogen and
other lacking gene (R) i.e. carrying gene for susceptibility (r) are inoculated with two
races of pathogen, one of which carries a gene for avirulence (A) and other carrying
the gene for virulence (a) against (R); it gives a 4 gene combinations as below:

7. Gene for gene hypothesis

8. Elicitor recognition
Elicitors in plant biology are extrinsic or foreign molecules often associated with plant
pests, diseases or synergistic organisms. Elicitor molecules can attach to special
receptor proteins located on plant cell membranes.
Example of elicitors:-

9. Elicitor recognition

10. Gene pyramiding
Gene pyramiding is mainly defined as a process of combing two or more genes from multiple
parents to develop elite lines and varieties. This leads to the simultaneous expression of more
than one gene in a variety. For pyramiding genes, breeders must calculate the probability of an
individual plant containing the desired combination of alleles.

11. “R” gene concept
Plants have evolved R genes (resistance genes) whose products mediate resistance to specific
virus, bacteria, oomycete, fungus, nematode or insect strains. R gene products are proteins that
allow recognition of specific pathogen effectors, either through direct binding or by recognition of the
effector's alteration of a host protein.

12. “R” gene concept
Location of 5 classes of R gene receptors in the cell

13. Components of disease resistance
Components of disease
resistance are:-
1. Pathogen detection
2. Signal transduction
3. Defence response
PRR: Pattern recognition
receptors;
WAK: wall-associated
kinases;
NLR: nucleotide-binding
domains and leucine-rich
repeats;
PDR: pathogen-derived
resistance;
HR: hypersensitive response;
TIR: N-terminal
Toll/interleukin-1 receptor-like;
CC: coiled-coil;
SA: salicylic acid;
JA: jasmonic acid.