Mitral regurgitation in hypertrophic cardiomyopathy is most often eccentric, as the primary mechanism is related to the faulty angle of attachment between the papillary muscles and mitral valve leaflets. If systolic anterior motion of the mitral valve is the cause, the jet of regurgitation will be directed posteriorly. The murmur of mitral regurgitation in hypertrophic cardiomyopathy is rarely pansystolic, as the mechanism of regurgitation begins after systole has started. It can be difficult to differentiate the murmur of mitral regurgitation from that of left ventricular outflow tract obstruction.