SlideShare a Scribd company logo
Sickle Cell Disease &
Total Hip Arthroplasty
The three principle
      orthopaedic
     manifestations
• pyogenic infections
• marrow hyperplasia
• osteonecrosis
       J Am Acad Orthop Surg 2005;13:208-217
Organisms

• Staphylococcus aureus
• Streptococcus pneumoniae
• Salmonella typhi,
• Klebsiella pneumoniae
        N Engl J Med 1999;340: 1021-1030
        Clin Orthop 1993;294:140-148
Marrow Hyperplasia


• Increased erythropoiesis
• widening of the medullary canal and
  thinning of the trabeculae and cortices,



        J Bone Joint Surg Br 1989;71: 465-470
Osteonecrosis

• hypoxia-induced erythrocyte sickling, along
    with extravascular compression of the
    intraosseous blood supply caused by
    medullary hyperplasia
•    bone or marrow infarction, focal and
    patchy areas
Patient Evaluation and
   Natural History

• Groin pain
• limited ROM
• Often bilateral
Nonsurgical
         Management

• pain management
• assistive devices
• typically progresses

        J Bone Joint Surg Am 2003;85:500-504
Surgical Management

• disabling hip pain
• severely damaged hip joint
• Medically fit
Surgical Management
• THA
• Core decompression
• Femoral osteotomy
• Arthrodesis
• Hemiarthroplasty
• Resection arthroplasty
• No Level 1 or 2 evidence
• Steinberg stages I and II

       J Am Acad Orthop Surg 2005;13:208-217
• it does not address the primary underlying
  pathophysiology of vaso-occlusion
• femoral head involvement usually is diffuse
  and too large to decompress
• chronic nature of the disease makes future
  infarcts inevitable despite decompression

            Am J Orthop 1995;24:18-24
Preoperative
       Considerations
• preventing sickle cell crises
• paying careful attention to cardiac status
  and fluid balance
• assessing infection
• using preoperative transfusion or
  plasmapheresis
• considering anesthetic modalities and pain
  management technique
Preoperative
      Considerations


• hemoglobin S level < 30%


  Am J Hematol. 1999 Nov;62(3):129-38
Intraoperative
       Considerations

• wide medullary canal an thin cortices
• sclerosis, and canal obliteration
Accetabular
  Preparation &
Component Insertion
• Acetabular bone quality may be poor
• patches of densely sclerotic bone
  (eccentric reaming
• acetabular protrusio ( medial reaming, Bone
  Graft, acetabular support and In-situ
  Osteotomy)
       J Am Acad Orthop Surg 2005;13:208-217
Femoral Canal
         Preparation
• Areas of sclerosis may be so diffuse that
  the canal becomes completely obliterated
• hyperplastic medullary canals, thin cortices
• introducing a drill bit under image
  intensifier until it is possible to insert a
  guidewire for flexible reamers

            Int Orthop 2002;26:157-161
Medical Complications

• excessive bleeding (18%)
• pulmonary complications
• sickle cell crises
• cardiac complications (4%)
• mental status changes
          Am J Hematol 1999;62:129-138
Surgical Complications
• Infection (25%)
 • There are no reported cases of
    Salmonella osteomyelitis complicating a
    THA; therefore, prophylactic
    administration of antibiotics that provide
    coverage for this gram-negative
    microorganism is not recommended
          Am J Orthop 1996;25: 353-356
          Clin Orthop 1993;294:140-148
Surgical Complications


• Hip Dislocation (26%)


          J Arthroplasty 1997;12:420-425

More Related Content

What's hot

MIA in Thoraco-lumbar Trauma (SPINE 2009)
MIA in Thoraco-lumbar Trauma (SPINE 2009)MIA in Thoraco-lumbar Trauma (SPINE 2009)
MIA in Thoraco-lumbar Trauma (SPINE 2009)
Prof. Dr. Mohamed Mohi Eldin
 
Sponk ppt
Sponk pptSponk ppt
Sponk ppt
Lokesh Sharoff
 
IATROGENIC GROIN PSEUDOANEURYSM MANAGEMENT
IATROGENIC GROIN PSEUDOANEURYSM MANAGEMENTIATROGENIC GROIN PSEUDOANEURYSM MANAGEMENT
IATROGENIC GROIN PSEUDOANEURYSM MANAGEMENT
Salvatore Ronsivalle
 
1362462786 amputation in diabetic foot
1362462786 amputation in diabetic foot1362462786 amputation in diabetic foot
1362462786 amputation in diabetic foot
dfsimedia
 
Vertebroplasty Grand Rounds
Vertebroplasty Grand RoundsVertebroplasty Grand Rounds
Vertebroplasty Grand Rounds
Vertebroplasty
 
Nmt631 skeletal anat, phys, bone scinti principles
Nmt631 skeletal anat, phys, bone scinti principlesNmt631 skeletal anat, phys, bone scinti principles
Nmt631 skeletal anat, phys, bone scinti principles
ljmcneill33
 
Calcific Tendinitis of the Rotator Cuff
Calcific Tendinitis of the Rotator Cuff Calcific Tendinitis of the Rotator Cuff
Calcific Tendinitis of the Rotator Cuff
Ade Wijaya
 
Case report iliac aneurysm
Case report iliac aneurysmCase report iliac aneurysm
Case report iliac aneurysm
Mannuel RodriGuez
 
Xlif in the treatment of ddd
Xlif in the treatment of dddXlif in the treatment of ddd
Xlif in the treatment of ddd
nicola zullo
 
Minimal invasive techniques in lumbar degenerative diseases
Minimal invasive techniques in lumbar degenerative diseasesMinimal invasive techniques in lumbar degenerative diseases
Minimal invasive techniques in lumbar degenerative diseases
Prof. Dr. Mohamed Mohi Eldin
 
mandibular orthognathic procedures II- ih
mandibular orthognathic procedures II- ihmandibular orthognathic procedures II- ih
mandibular orthognathic procedures II- ih
itrat hussain
 
Vertebral Augmentation by Vertebroplasty and Kyphoplasty: Introductory concerns
Vertebral Augmentation by Vertebroplasty and Kyphoplasty: Introductory concernsVertebral Augmentation by Vertebroplasty and Kyphoplasty: Introductory concerns
Vertebral Augmentation by Vertebroplasty and Kyphoplasty: Introductory concerns
Prof. Dr. Mohamed Mohi Eldin
 
The Bone Scan
The Bone ScanThe Bone Scan
The Bone Scan
lahollenbeck
 
Management of Femoral Head Osteonecrosis.
Management of Femoral Head Osteonecrosis.Management of Femoral Head Osteonecrosis.
Management of Femoral Head Osteonecrosis.
Dr.Anshu Sharma
 
Ewings sarcoma- BONE TUMORS
Ewings sarcoma- BONE TUMORS Ewings sarcoma- BONE TUMORS
Ewings sarcoma- BONE TUMORS
Dr.Nikhil. S.U
 
urethroplasty
 urethroplasty urethroplasty
urethroplasty
DRTALALBALLOUT
 
Diskitis
DiskitisDiskitis
Diskitis
PratikDhabalia
 
Patients with myelomeningocele and
Patients with myelomeningocele andPatients with myelomeningocele and
Patients with myelomeningocele and
fisioterapia_estudio
 
Aneurysmal Bone Cyst of the Spine | Crimson Publishers
Aneurysmal Bone Cyst of the Spine | Crimson PublishersAneurysmal Bone Cyst of the Spine | Crimson Publishers
Aneurysmal Bone Cyst of the Spine | Crimson Publishers
CrimsonPublishersTNN
 
Peyronie's Disease: a tailored surgical procedure for every patient
Peyronie's Disease: a tailored surgical procedure for every patientPeyronie's Disease: a tailored surgical procedure for every patient
Peyronie's Disease: a tailored surgical procedure for every patient
Men's Health International Surgical Center
 

What's hot (20)

MIA in Thoraco-lumbar Trauma (SPINE 2009)
MIA in Thoraco-lumbar Trauma (SPINE 2009)MIA in Thoraco-lumbar Trauma (SPINE 2009)
MIA in Thoraco-lumbar Trauma (SPINE 2009)
 
Sponk ppt
Sponk pptSponk ppt
Sponk ppt
 
IATROGENIC GROIN PSEUDOANEURYSM MANAGEMENT
IATROGENIC GROIN PSEUDOANEURYSM MANAGEMENTIATROGENIC GROIN PSEUDOANEURYSM MANAGEMENT
IATROGENIC GROIN PSEUDOANEURYSM MANAGEMENT
 
1362462786 amputation in diabetic foot
1362462786 amputation in diabetic foot1362462786 amputation in diabetic foot
1362462786 amputation in diabetic foot
 
Vertebroplasty Grand Rounds
Vertebroplasty Grand RoundsVertebroplasty Grand Rounds
Vertebroplasty Grand Rounds
 
Nmt631 skeletal anat, phys, bone scinti principles
Nmt631 skeletal anat, phys, bone scinti principlesNmt631 skeletal anat, phys, bone scinti principles
Nmt631 skeletal anat, phys, bone scinti principles
 
Calcific Tendinitis of the Rotator Cuff
Calcific Tendinitis of the Rotator Cuff Calcific Tendinitis of the Rotator Cuff
Calcific Tendinitis of the Rotator Cuff
 
Case report iliac aneurysm
Case report iliac aneurysmCase report iliac aneurysm
Case report iliac aneurysm
 
Xlif in the treatment of ddd
Xlif in the treatment of dddXlif in the treatment of ddd
Xlif in the treatment of ddd
 
Minimal invasive techniques in lumbar degenerative diseases
Minimal invasive techniques in lumbar degenerative diseasesMinimal invasive techniques in lumbar degenerative diseases
Minimal invasive techniques in lumbar degenerative diseases
 
mandibular orthognathic procedures II- ih
mandibular orthognathic procedures II- ihmandibular orthognathic procedures II- ih
mandibular orthognathic procedures II- ih
 
Vertebral Augmentation by Vertebroplasty and Kyphoplasty: Introductory concerns
Vertebral Augmentation by Vertebroplasty and Kyphoplasty: Introductory concernsVertebral Augmentation by Vertebroplasty and Kyphoplasty: Introductory concerns
Vertebral Augmentation by Vertebroplasty and Kyphoplasty: Introductory concerns
 
The Bone Scan
The Bone ScanThe Bone Scan
The Bone Scan
 
Management of Femoral Head Osteonecrosis.
Management of Femoral Head Osteonecrosis.Management of Femoral Head Osteonecrosis.
Management of Femoral Head Osteonecrosis.
 
Ewings sarcoma- BONE TUMORS
Ewings sarcoma- BONE TUMORS Ewings sarcoma- BONE TUMORS
Ewings sarcoma- BONE TUMORS
 
urethroplasty
 urethroplasty urethroplasty
urethroplasty
 
Diskitis
DiskitisDiskitis
Diskitis
 
Patients with myelomeningocele and
Patients with myelomeningocele andPatients with myelomeningocele and
Patients with myelomeningocele and
 
Aneurysmal Bone Cyst of the Spine | Crimson Publishers
Aneurysmal Bone Cyst of the Spine | Crimson PublishersAneurysmal Bone Cyst of the Spine | Crimson Publishers
Aneurysmal Bone Cyst of the Spine | Crimson Publishers
 
Peyronie's Disease: a tailored surgical procedure for every patient
Peyronie's Disease: a tailored surgical procedure for every patientPeyronie's Disease: a tailored surgical procedure for every patient
Peyronie's Disease: a tailored surgical procedure for every patient
 

Viewers also liked

Ctev
CtevCtev
Congenital clubfoot
Congenital clubfootCongenital clubfoot
Congenital clubfoot
Yasser Alwabli
 
Total hip replacement in sickle cell disease
Total hip replacement in sickle cell diseaseTotal hip replacement in sickle cell disease
Total hip replacement in sickle cell disease
jatinder12345
 
Elbow arthroplasty associated with distal humerus fracture -spanish - Hovsepian
Elbow arthroplasty associated with distal humerus fracture -spanish - HovsepianElbow arthroplasty associated with distal humerus fracture -spanish - Hovsepian
Elbow arthroplasty associated with distal humerus fracture -spanish - Hovsepian
Jean Michel Hovsepian
 
Management of club foot
Management of club footManagement of club foot
Management of club foot
Hardik Pawar
 
Club foot
Club footClub foot

Viewers also liked (6)

Ctev
CtevCtev
Ctev
 
Congenital clubfoot
Congenital clubfootCongenital clubfoot
Congenital clubfoot
 
Total hip replacement in sickle cell disease
Total hip replacement in sickle cell diseaseTotal hip replacement in sickle cell disease
Total hip replacement in sickle cell disease
 
Elbow arthroplasty associated with distal humerus fracture -spanish - Hovsepian
Elbow arthroplasty associated with distal humerus fracture -spanish - HovsepianElbow arthroplasty associated with distal humerus fracture -spanish - Hovsepian
Elbow arthroplasty associated with distal humerus fracture -spanish - Hovsepian
 
Management of club foot
Management of club footManagement of club foot
Management of club foot
 
Club foot
Club footClub foot
Club foot
 

Similar to Hip

Avn of femoral head
Avn of femoral headAvn of femoral head
Avn of femoral head
BhaskarRaJ14
 
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...
drashraf369
 
Avascular Necrosis of Hip
Avascular Necrosis of HipAvascular Necrosis of Hip
Avascular Necrosis of Hip
Sijan Bhattachan
 
peripherial arterial disease
peripherial arterial diseaseperipherial arterial disease
peripherial arterial disease
Note Noteenote
 
Spinal stenosis
Spinal stenosisSpinal stenosis
Spinal stenosis
Mukhtar Khan
 
Early results of operative management of acetabular fracture
Early results of operative management of acetabular fractureEarly results of operative management of acetabular fracture
Early results of operative management of acetabular fracture
AAU-Sudan/McMaster University/HHSC
 
Avascular necrosis of femoral head 1456920705296
Avascular necrosis of femoral head 1456920705296Avascular necrosis of femoral head 1456920705296
Avascular necrosis of femoral head 1456920705296
Gaurav Singh
 
Chronic osteomyelitis
Chronic osteomyelitisChronic osteomyelitis
Chronic osteomyelitis
Mohamed Jukaku
 
Osteosarcoma.pptx
Osteosarcoma.pptxOsteosarcoma.pptx
Osteosarcoma.pptx
anu aggrawal
 
Foot ankle trauma 2013
Foot ankle trauma 2013Foot ankle trauma 2013
Foot ankle trauma 2013
Winston Rennie
 
Spinal infections
Spinal infectionsSpinal infections
Spinal infections
RejoyceAnto
 
=====CHARCOT NEUROARTHROPATHY===========
=====CHARCOT NEUROARTHROPATHY================CHARCOT NEUROARTHROPATHY===========
=====CHARCOT NEUROARTHROPATHY===========
FairuzKhamzah
 
Anesthetic implications of TOTAL HIP REPLACEMENT and TOTAL KNEE Replacement s...
Anesthetic implications of TOTAL HIP REPLACEMENT and TOTAL KNEE Replacement s...Anesthetic implications of TOTAL HIP REPLACEMENT and TOTAL KNEE Replacement s...
Anesthetic implications of TOTAL HIP REPLACEMENT and TOTAL KNEE Replacement s...
Farooq Yadwad
 
Knee pain
Knee painKnee pain
Knee pain
Apicare Journal
 
Malignant Otitis Externa/ Skull Base osteomyelitis
Malignant Otitis Externa/ Skull Base osteomyelitisMalignant Otitis Externa/ Skull Base osteomyelitis
Malignant Otitis Externa/ Skull Base osteomyelitis
Omar Farooq
 
Cardiac cath complications
Cardiac cath complicationsCardiac cath complications
Cardiac cath complications
Fuad Farooq
 
Avascular necrosis of head of femur.pptx
Avascular necrosis of head of femur.pptxAvascular necrosis of head of femur.pptx
Avascular necrosis of head of femur.pptx
DibashjyotiDutta
 
Avascular Necrosis (AVN)
Avascular Necrosis (AVN)Avascular Necrosis (AVN)
Avascular Necrosis (AVN)
Salihi Abdulmalik
 
Vertebroplasty vs Kyphoplasty
Vertebroplasty vs KyphoplastyVertebroplasty vs Kyphoplasty
Vertebroplasty vs Kyphoplasty
Alexander Bardis
 
Surgical treatment acute dvt
Surgical treatment acute dvtSurgical treatment acute dvt
Surgical treatment acute dvt
uvcd
 

Similar to Hip (20)

Avn of femoral head
Avn of femoral headAvn of femoral head
Avn of femoral head
 
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...
 
Avascular Necrosis of Hip
Avascular Necrosis of HipAvascular Necrosis of Hip
Avascular Necrosis of Hip
 
peripherial arterial disease
peripherial arterial diseaseperipherial arterial disease
peripherial arterial disease
 
Spinal stenosis
Spinal stenosisSpinal stenosis
Spinal stenosis
 
Early results of operative management of acetabular fracture
Early results of operative management of acetabular fractureEarly results of operative management of acetabular fracture
Early results of operative management of acetabular fracture
 
Avascular necrosis of femoral head 1456920705296
Avascular necrosis of femoral head 1456920705296Avascular necrosis of femoral head 1456920705296
Avascular necrosis of femoral head 1456920705296
 
Chronic osteomyelitis
Chronic osteomyelitisChronic osteomyelitis
Chronic osteomyelitis
 
Osteosarcoma.pptx
Osteosarcoma.pptxOsteosarcoma.pptx
Osteosarcoma.pptx
 
Foot ankle trauma 2013
Foot ankle trauma 2013Foot ankle trauma 2013
Foot ankle trauma 2013
 
Spinal infections
Spinal infectionsSpinal infections
Spinal infections
 
=====CHARCOT NEUROARTHROPATHY===========
=====CHARCOT NEUROARTHROPATHY================CHARCOT NEUROARTHROPATHY===========
=====CHARCOT NEUROARTHROPATHY===========
 
Anesthetic implications of TOTAL HIP REPLACEMENT and TOTAL KNEE Replacement s...
Anesthetic implications of TOTAL HIP REPLACEMENT and TOTAL KNEE Replacement s...Anesthetic implications of TOTAL HIP REPLACEMENT and TOTAL KNEE Replacement s...
Anesthetic implications of TOTAL HIP REPLACEMENT and TOTAL KNEE Replacement s...
 
Knee pain
Knee painKnee pain
Knee pain
 
Malignant Otitis Externa/ Skull Base osteomyelitis
Malignant Otitis Externa/ Skull Base osteomyelitisMalignant Otitis Externa/ Skull Base osteomyelitis
Malignant Otitis Externa/ Skull Base osteomyelitis
 
Cardiac cath complications
Cardiac cath complicationsCardiac cath complications
Cardiac cath complications
 
Avascular necrosis of head of femur.pptx
Avascular necrosis of head of femur.pptxAvascular necrosis of head of femur.pptx
Avascular necrosis of head of femur.pptx
 
Avascular Necrosis (AVN)
Avascular Necrosis (AVN)Avascular Necrosis (AVN)
Avascular Necrosis (AVN)
 
Vertebroplasty vs Kyphoplasty
Vertebroplasty vs KyphoplastyVertebroplasty vs Kyphoplasty
Vertebroplasty vs Kyphoplasty
 
Surgical treatment acute dvt
Surgical treatment acute dvtSurgical treatment acute dvt
Surgical treatment acute dvt
 

Recently uploaded

TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
rightmanforbloodline
 
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
bkling
 
CBL Seminar 2024_Preliminary Program.pdf
CBL Seminar 2024_Preliminary Program.pdfCBL Seminar 2024_Preliminary Program.pdf
CBL Seminar 2024_Preliminary Program.pdf
suvadeepdas911
 
Chapter 11 Nutrition and Chronic Diseases.pptx
Chapter 11 Nutrition and Chronic Diseases.pptxChapter 11 Nutrition and Chronic Diseases.pptx
Chapter 11 Nutrition and Chronic Diseases.pptx
Earlene McNair
 
Diabetic nephropathy diagnosis treatment
Diabetic nephropathy diagnosis treatmentDiabetic nephropathy diagnosis treatment
Diabetic nephropathy diagnosis treatment
arahmanzai5
 
Abortion PG Seminar Power point presentation
Abortion PG Seminar Power point presentationAbortion PG Seminar Power point presentation
Abortion PG Seminar Power point presentation
AksshayaRajanbabu
 
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptxEar and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Dr. Rabia Inam Gandapore
 
Aortic Association CBL Pilot April 19 – 20 Bern
Aortic Association CBL Pilot April 19 – 20 BernAortic Association CBL Pilot April 19 – 20 Bern
Aortic Association CBL Pilot April 19 – 20 Bern
suvadeepdas911
 
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachIntegrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Ayurveda ForAll
 
A Classical Text Review on Basavarajeeyam
A Classical Text Review on BasavarajeeyamA Classical Text Review on Basavarajeeyam
A Classical Text Review on Basavarajeeyam
Dr. Jyothirmai Paindla
 
Tests for analysis of different pharmaceutical.pptx
Tests for analysis of different pharmaceutical.pptxTests for analysis of different pharmaceutical.pptx
Tests for analysis of different pharmaceutical.pptx
taiba qazi
 
Ketone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistryKetone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistry
Dhayanithi C
 
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune DiseaseCell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
Health Advances
 
Role of Mukta Pishti in the Management of Hyperthyroidism
Role of Mukta Pishti in the Management of HyperthyroidismRole of Mukta Pishti in the Management of Hyperthyroidism
Role of Mukta Pishti in the Management of Hyperthyroidism
Dr. Jyothirmai Paindla
 
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.GawadHemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
NephroTube - Dr.Gawad
 
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Oleg Kshivets
 
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptxVestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Dr. Rabia Inam Gandapore
 
Efficacy of Avartana Sneha in Ayurveda
Efficacy of Avartana Sneha in AyurvedaEfficacy of Avartana Sneha in Ayurveda
Efficacy of Avartana Sneha in Ayurveda
Dr. Jyothirmai Paindla
 
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
rightmanforbloodline
 
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxDoes Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
walterHu5
 

Recently uploaded (20)

TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
 
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
 
CBL Seminar 2024_Preliminary Program.pdf
CBL Seminar 2024_Preliminary Program.pdfCBL Seminar 2024_Preliminary Program.pdf
CBL Seminar 2024_Preliminary Program.pdf
 
Chapter 11 Nutrition and Chronic Diseases.pptx
Chapter 11 Nutrition and Chronic Diseases.pptxChapter 11 Nutrition and Chronic Diseases.pptx
Chapter 11 Nutrition and Chronic Diseases.pptx
 
Diabetic nephropathy diagnosis treatment
Diabetic nephropathy diagnosis treatmentDiabetic nephropathy diagnosis treatment
Diabetic nephropathy diagnosis treatment
 
Abortion PG Seminar Power point presentation
Abortion PG Seminar Power point presentationAbortion PG Seminar Power point presentation
Abortion PG Seminar Power point presentation
 
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptxEar and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
 
Aortic Association CBL Pilot April 19 – 20 Bern
Aortic Association CBL Pilot April 19 – 20 BernAortic Association CBL Pilot April 19 – 20 Bern
Aortic Association CBL Pilot April 19 – 20 Bern
 
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachIntegrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
 
A Classical Text Review on Basavarajeeyam
A Classical Text Review on BasavarajeeyamA Classical Text Review on Basavarajeeyam
A Classical Text Review on Basavarajeeyam
 
Tests for analysis of different pharmaceutical.pptx
Tests for analysis of different pharmaceutical.pptxTests for analysis of different pharmaceutical.pptx
Tests for analysis of different pharmaceutical.pptx
 
Ketone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistryKetone bodies and metabolism-biochemistry
Ketone bodies and metabolism-biochemistry
 
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune DiseaseCell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
 
Role of Mukta Pishti in the Management of Hyperthyroidism
Role of Mukta Pishti in the Management of HyperthyroidismRole of Mukta Pishti in the Management of Hyperthyroidism
Role of Mukta Pishti in the Management of Hyperthyroidism
 
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.GawadHemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
 
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
 
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptxVestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
 
Efficacy of Avartana Sneha in Ayurveda
Efficacy of Avartana Sneha in AyurvedaEfficacy of Avartana Sneha in Ayurveda
Efficacy of Avartana Sneha in Ayurveda
 
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
 
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxDoes Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
 

Hip

  • 1. Sickle Cell Disease & Total Hip Arthroplasty
  • 2. The three principle orthopaedic manifestations • pyogenic infections • marrow hyperplasia • osteonecrosis J Am Acad Orthop Surg 2005;13:208-217
  • 3. Organisms • Staphylococcus aureus • Streptococcus pneumoniae • Salmonella typhi, • Klebsiella pneumoniae N Engl J Med 1999;340: 1021-1030 Clin Orthop 1993;294:140-148
  • 4. Marrow Hyperplasia • Increased erythropoiesis • widening of the medullary canal and thinning of the trabeculae and cortices, J Bone Joint Surg Br 1989;71: 465-470
  • 5. Osteonecrosis • hypoxia-induced erythrocyte sickling, along with extravascular compression of the intraosseous blood supply caused by medullary hyperplasia • bone or marrow infarction, focal and patchy areas
  • 6. Patient Evaluation and Natural History • Groin pain • limited ROM • Often bilateral
  • 7. Nonsurgical Management • pain management • assistive devices • typically progresses J Bone Joint Surg Am 2003;85:500-504
  • 8. Surgical Management • disabling hip pain • severely damaged hip joint • Medically fit
  • 9. Surgical Management • THA • Core decompression • Femoral osteotomy • Arthrodesis • Hemiarthroplasty • Resection arthroplasty
  • 10. • No Level 1 or 2 evidence • Steinberg stages I and II J Am Acad Orthop Surg 2005;13:208-217
  • 11. • it does not address the primary underlying pathophysiology of vaso-occlusion • femoral head involvement usually is diffuse and too large to decompress • chronic nature of the disease makes future infarcts inevitable despite decompression Am J Orthop 1995;24:18-24
  • 12. Preoperative Considerations • preventing sickle cell crises • paying careful attention to cardiac status and fluid balance • assessing infection • using preoperative transfusion or plasmapheresis • considering anesthetic modalities and pain management technique
  • 13. Preoperative Considerations • hemoglobin S level < 30% Am J Hematol. 1999 Nov;62(3):129-38
  • 14. Intraoperative Considerations • wide medullary canal an thin cortices • sclerosis, and canal obliteration
  • 15. Accetabular Preparation & Component Insertion • Acetabular bone quality may be poor • patches of densely sclerotic bone (eccentric reaming • acetabular protrusio ( medial reaming, Bone Graft, acetabular support and In-situ Osteotomy) J Am Acad Orthop Surg 2005;13:208-217
  • 16. Femoral Canal Preparation • Areas of sclerosis may be so diffuse that the canal becomes completely obliterated • hyperplastic medullary canals, thin cortices • introducing a drill bit under image intensifier until it is possible to insert a guidewire for flexible reamers Int Orthop 2002;26:157-161
  • 17. Medical Complications • excessive bleeding (18%) • pulmonary complications • sickle cell crises • cardiac complications (4%) • mental status changes Am J Hematol 1999;62:129-138
  • 18. Surgical Complications • Infection (25%) • There are no reported cases of Salmonella osteomyelitis complicating a THA; therefore, prophylactic administration of antibiotics that provide coverage for this gram-negative microorganism is not recommended Am J Orthop 1996;25: 353-356 Clin Orthop 1993;294:140-148
  • 19. Surgical Complications • Hip Dislocation (26%) J Arthroplasty 1997;12:420-425