The document discusses two pig blood-derived products - Hide (meat) Glue and Spray Dried Porcine Plasma (SDPP). Hide glue is used to bind pieces of meat and is derived from cattle and pig blood but is not tested for hepatitis E virus (HEV). A study found that 100% of tested SDPP batches contained HEV antibodies and 22.4% tested positive for HEV RNA, posing risks for HEV transmission. The Dutch Food Safety Authority plans to incorporate HEV into food safety plans and start monitoring projects for Hide Glue in 2016.

1. “Hide(meat) Glue”
●Used for glueing pieces of meat:
› Steaks, Ham, Beefsteak, Pork tenderloin
●Thrombine and Fibrinogen derived from Cattle/Pig blood.
Dutch FSA approved animals (not-tested for HEV)
●No HEV-inactivating production step
●Endproduct not tested for HEV
●Risk-control: now (erronously) retailer/consumer
●Mandatory on productwrapper “Pig Protein” “Varkenseiwit”
●Production 2014: 175.000 kg
ECDC- HEV-Exp meeting , Stockholm, 9,10 Dec 2015

2. Spray Dried Porcine Plasma (SDPP)
● Hide (meat) Glue ≠ SDPP
● SDPP production (spray drying ~15 seconds 220 – 80 C):
Inactivation HEV?
● SDPP is used for:
● binding fats and water
● colouring food products
● Animal feed (piglets)
● Total production 2014 SDPP (1 big producer):
13.000.000 kg
ECDC- HEV-Exp meeting , Stockholm, 9,10 Dec 2015

3. Spray Dried Porcine Plasma (SDPP)
● Pujols et al. Virology Journal 2014, 11:232:
› 100 % tested SDPP batches HEV AB present
› 22,4% HEV RNA +
› HEV RNA in SDPP batches fed to pigs: no HEV seroconversion…….
– Meaning for Hide/Meat Glue and other pig blood derived
products?
Action plan Dutch FSA, Hide Glue:
●HEV incorporating in the “foodsafetyplan”
●Monitoring-project, starting in 2016
ECDC- HEV-Exp meeting , Stockholm, 9,10 Dec 2015