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HC 177: Biotechnology & Art

The Human Chloroplast Project
Caryn Brenn
Physiological Science Major
Abstract

       The Human Chloroplast Project takes the properties of
 photosynthesis used by plants and places them into individuals.
 The project allows humans to make their own food (glucose) using
 energy from the sun and carbon dioxide waste. Chloroplasts will
 be concentrated into a microchip and implanted into an
 individuals’ hand. The glucose will be transported into the blood
 and used to make energy via metabolic respiration. The goal of
 the project is not only create a work of bioart but also to help
 alleviate the global problem of hunger and starvation. The future of
 this project holds promise of transgenic insertion. Possible
 complications include cultural sensitivity, affordability, and issues
 of vitamins and nutrition.
World Hunger
      Everyday, all around the world people are dying from
hunger. To be more precise, every 3.6 seconds someone
dies of hunger. The World Health Organization estimates that
one-third of the world is well-fed, one-third is under-fed one-
third is starving. While it is often assume that starvation is only
occurring in under-developed countries, it is the unfortunate
truth that it is happening here is the US as well. One out of
every eight children under the age of twelve in the U.S.
goes to bed hungry every night.
      Carbohydrates are organic compounds that are rich in
starch and make up a essential part of the human diet. This
includes cereals, bread, pasta, and simple sugars. During
digestion, carbohydrates that we consume are broken down
into monosaccharides, such as glucose, and are used by our
cells for energy production.
Chloroplasts and Photosynthesis

  Chloroplasts are organelles found in plant cells that carry out
  photosynthesis. They use energy from the sun to convert
  carbon dioxide and water into glucose and oxygen.
                       Photosynthesis



  Humans use cellular respiration, converting monosaccharides
  and oxygen into energy and carbon dioxide waste.
                         Respiration
The Human Chloroplast Project

     My project will take chloroplasts from
 plants, concentrate them into a microchip, and
 implant them into individuals. Individuals will then be
 able to carry out both photosynthesis and cellular
 respiration on their own, essentially creating their
 own food.



                              +
The Human Chloroplast Project

      The chloroplasts will be
 hooked up to the portal
 system, removing carbon
 dioxide and water from the
 blood and adding oxygen and
 glucose. Ideally, the chip
 would be placed. near the
 lungs where carbon dioxide is
 exchanged for oxygen.
 However, in order to reduce
 invasiveness and make
 exposure to light easier, the
 chip will be placed in the hand
 or forearm of the individual.
The Human Chloroplast Project

 The project will initially involve implantation of a microchip and
 if success could evolve into a transgenic implantation. The
 chloroplast gene will be inserted into the DNA of specific
 cells, not the whole individual (we don’t want green humans!!).
 Transgenic cells will be located in an area that can be easily
 exposed to light. Transgenic mutation would also be more
 efficient in that the chloroplasts would be located within the
 cells, spatially near the mitochondria.
Conclusion

  The Human Chloroplast Project will implant chloroplasts into
  humans allowing them to create their own glucose using
  sunlight and hopefully reducing hunger across the world. This
  project will impact the food industry by reducing demand for
  grains and carbohydrates and increasing demands and
  allowing for more resources to be focused on production of
  produce and meats.


Possible Complications
-Cultural Sensitivity
-Affordability
-Nutrition, Vitamins
References

   Eduardo Kac, GFP Bunny
   KAC. Eduardo Kac. Web. 12 Feb. 2010.
    <http://www.ekac.org/>.
   Laura Cinti, Cactus Hair
   "C-lab | THE CACTUS PROJECT." C-lab | INTO THE LABS.
    Web. 12 Feb. 2010. <http://c-
    lab.co.uk/default.aspx?id=9&projectid=2>.
   Outlaw Biology, UCLA
   OUTLAW BIOLOGY? Web. 12 Feb. 2010.
    <http://outlawbiology.net/>.
Bibliography
   "Cell Organelles: The Chloroplast." Home of CELLS alive! Web. 12 Feb. 2010.
    <http://www.cellsalive.com/cells/chloropl.htm>.
   DIYbio. Jason Bobe. Web. 12 Feb. 2010. <http://diybio.org/>.
   "The Ecological Impacts of Agricultural Biotechnology (ActionBioscience)."
    ActionBioscience - promoting bioscience literacy. Web. 12 Feb. 2010.
    <http://www.actionbioscience.org/biotech/altieri.html>.
   Guo, H., Yang, H., Mockler, T., Lin, C., (1998) "Regulation of Flowering Time by
    Arabidopsis Photoreceptors." Science 279:1360-1363.
   Horton, Sue, Harold Alderman, and Juan Rivera. "Hunger and Malnutrition." Copenhagen
    Consensus 2008 Challenge Paper (2008). World Health Organization. Web.
    <http://www.who.int/pmnch/topics/maternal/hunger_malnutrition/en/>.
   "The New York Times Log In." The New York Times. Web. 12 Feb. 2010.
    <http://www.nytimes.com/2008/10/04/opinion/04sat3.html?_r=1>.
   "PHOTOSYNTHESIS." Www.estrellamountain.edu. Web. 12 Feb. 2010.
    <http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookPS.html>.
   "What are transgenic foods? (EUFIC)." The European Food Information Council (EUFIC) :
    Your guide to food safety & quality and health & nutrition for a balanced diet and healthy
    lifestyle. Web. 12 Feb. 2010. <http://www.eufic.org/page/en/faqid/transgenic-foods/>.
   "WHO | Biotechnology (GM foods) and nanotechnology." Web. 12 Feb. 2010.
    <http://www.who.int/foodsafety/biotech/en/>.
   "The world hunger problem: Facts, figures and statistics." Oracle ThinkQuest Library. Web.
    12 Feb. 2010. <http://library.thinkquest.org/C002291/high/present/stats.htm>.

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HC 177: Biotechnology & Art - "Human Chloroplast Project

  • 1. HC 177: Biotechnology & Art The Human Chloroplast Project Caryn Brenn Physiological Science Major
  • 2. Abstract The Human Chloroplast Project takes the properties of photosynthesis used by plants and places them into individuals. The project allows humans to make their own food (glucose) using energy from the sun and carbon dioxide waste. Chloroplasts will be concentrated into a microchip and implanted into an individuals’ hand. The glucose will be transported into the blood and used to make energy via metabolic respiration. The goal of the project is not only create a work of bioart but also to help alleviate the global problem of hunger and starvation. The future of this project holds promise of transgenic insertion. Possible complications include cultural sensitivity, affordability, and issues of vitamins and nutrition.
  • 3. World Hunger Everyday, all around the world people are dying from hunger. To be more precise, every 3.6 seconds someone dies of hunger. The World Health Organization estimates that one-third of the world is well-fed, one-third is under-fed one- third is starving. While it is often assume that starvation is only occurring in under-developed countries, it is the unfortunate truth that it is happening here is the US as well. One out of every eight children under the age of twelve in the U.S. goes to bed hungry every night. Carbohydrates are organic compounds that are rich in starch and make up a essential part of the human diet. This includes cereals, bread, pasta, and simple sugars. During digestion, carbohydrates that we consume are broken down into monosaccharides, such as glucose, and are used by our cells for energy production.
  • 4. Chloroplasts and Photosynthesis Chloroplasts are organelles found in plant cells that carry out photosynthesis. They use energy from the sun to convert carbon dioxide and water into glucose and oxygen. Photosynthesis Humans use cellular respiration, converting monosaccharides and oxygen into energy and carbon dioxide waste. Respiration
  • 5. The Human Chloroplast Project My project will take chloroplasts from plants, concentrate them into a microchip, and implant them into individuals. Individuals will then be able to carry out both photosynthesis and cellular respiration on their own, essentially creating their own food. +
  • 6. The Human Chloroplast Project The chloroplasts will be hooked up to the portal system, removing carbon dioxide and water from the blood and adding oxygen and glucose. Ideally, the chip would be placed. near the lungs where carbon dioxide is exchanged for oxygen. However, in order to reduce invasiveness and make exposure to light easier, the chip will be placed in the hand or forearm of the individual.
  • 7. The Human Chloroplast Project The project will initially involve implantation of a microchip and if success could evolve into a transgenic implantation. The chloroplast gene will be inserted into the DNA of specific cells, not the whole individual (we don’t want green humans!!). Transgenic cells will be located in an area that can be easily exposed to light. Transgenic mutation would also be more efficient in that the chloroplasts would be located within the cells, spatially near the mitochondria.
  • 8. Conclusion The Human Chloroplast Project will implant chloroplasts into humans allowing them to create their own glucose using sunlight and hopefully reducing hunger across the world. This project will impact the food industry by reducing demand for grains and carbohydrates and increasing demands and allowing for more resources to be focused on production of produce and meats. Possible Complications -Cultural Sensitivity -Affordability -Nutrition, Vitamins
  • 9. References  Eduardo Kac, GFP Bunny  KAC. Eduardo Kac. Web. 12 Feb. 2010. <http://www.ekac.org/>.  Laura Cinti, Cactus Hair  "C-lab | THE CACTUS PROJECT." C-lab | INTO THE LABS. Web. 12 Feb. 2010. <http://c- lab.co.uk/default.aspx?id=9&projectid=2>.  Outlaw Biology, UCLA  OUTLAW BIOLOGY? Web. 12 Feb. 2010. <http://outlawbiology.net/>.
  • 10. Bibliography  "Cell Organelles: The Chloroplast." Home of CELLS alive! Web. 12 Feb. 2010. <http://www.cellsalive.com/cells/chloropl.htm>.  DIYbio. Jason Bobe. Web. 12 Feb. 2010. <http://diybio.org/>.  "The Ecological Impacts of Agricultural Biotechnology (ActionBioscience)." ActionBioscience - promoting bioscience literacy. Web. 12 Feb. 2010. <http://www.actionbioscience.org/biotech/altieri.html>.  Guo, H., Yang, H., Mockler, T., Lin, C., (1998) "Regulation of Flowering Time by Arabidopsis Photoreceptors." Science 279:1360-1363.  Horton, Sue, Harold Alderman, and Juan Rivera. "Hunger and Malnutrition." Copenhagen Consensus 2008 Challenge Paper (2008). World Health Organization. Web. <http://www.who.int/pmnch/topics/maternal/hunger_malnutrition/en/>.  "The New York Times Log In." The New York Times. Web. 12 Feb. 2010. <http://www.nytimes.com/2008/10/04/opinion/04sat3.html?_r=1>.  "PHOTOSYNTHESIS." Www.estrellamountain.edu. Web. 12 Feb. 2010. <http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookPS.html>.  "What are transgenic foods? (EUFIC)." The European Food Information Council (EUFIC) : Your guide to food safety & quality and health & nutrition for a balanced diet and healthy lifestyle. Web. 12 Feb. 2010. <http://www.eufic.org/page/en/faqid/transgenic-foods/>.  "WHO | Biotechnology (GM foods) and nanotechnology." Web. 12 Feb. 2010. <http://www.who.int/foodsafety/biotech/en/>.  "The world hunger problem: Facts, figures and statistics." Oracle ThinkQuest Library. Web. 12 Feb. 2010. <http://library.thinkquest.org/C002291/high/present/stats.htm>.