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Copyright © 2015 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chapter 20
Metabolism, Nutrition,
and Body Temperature
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Overview
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Key Terms
anabolism glycogen metabolic rate
basal metabolism glycolysis mineral
catabolism hypothalamus oxidation
cellular respiration hypothermia pyrogen
fever kilocalorie vitamin
glucose malnutrition
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Metabolism
Learning Objectives
1. Differentiate between catabolism
and anabolism.
2. Differentiate between the anaerobic
and aerobic phases of glucose
catabolism and give the end products
and the relative amount of energy
released by each.
3.Define metabolic rate and name six
factors that affect it.
4. Explain how carbohydrates,
fats, and proteins are metabolized for
energy.
5. Compare the energy contents of
carbohydrates, fats, and proteins.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines
Learning Objectives
6.List the recommended percentages of
carbohydrate, fat, and protein in the diet.
7. Distinguish between simple and
complex carbohydrates, giving examples
of each.
8.Compare saturated and unsaturated
fats.
9. Define essential amino acid.
10. Explain the roles of minerals and
vitamins in nutrition and give examples
of each.
11. List six adverse effects of alcohol
consumption.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Disorders
Learning Objective
12. Describe four nutritional
disorders.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Body Temperature
Learning Objectives
13. Explain how heat is produced
and lost in the body.
14. Describe the role of the hypothalamus
in regulating body temperature.
15. Explain the role of fever in disease.
16. Describe responses to excessive heat
and cold.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Case Study
Learning Objective
17. Using the case study
and the text, define
anorexia nervosa, and list
some of its adverse effects.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Word Anatomy
Learning Objective
18. Show how word parts are used to build words
related to metabolism, nutrition, and body
temperature.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Metabolism
Types of Metabolic Activities
•Catabolism
– Breaks down complex compounds into simpler
compounds
•Anabolism
– Builds simple compounds into needed substances
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Metabolism (cont.)
Cellular Respiration
•Glucose catabolism: anaerobic phase (glycolysis)
– Location: Cytoplasm
– Yield: 2 ATP per glucose molecule
– End product: Pyruvic acid
•Glucose catabolism: Aerobic phase
– Location: Mitochondria
– Yield: 32 ATP per glucose molecule
– End products: CO2 and H2O
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Metabolism (cont.)
Cellular Respiration (cont.)
•Cellular respiration of fatty acids and amino acids
– Oxidized to generate energy through aerobic
mechanisms
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Figure 20-1 Cellular respiration.
What does pyruvic acid produce when it is metabolized
anaerobically? What does it produce when metabolized
completely using oxygen?
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Metabolism (cont.)
Metabolic Rate
•Rate at which cellular respiration converts nutrients into
ATP
•Decreases with age
•Basal metabolism
•Measured in kilocalories (kcal)
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Metabolism (cont.)
Nutrient Metabolism
•Carbohydrates
– Glucose is the major energy source for cells.
– Glycogen is storage form of carbohydrates.
• Glycogen broken down to yield glucose.
– Excess glucose converted to fat and stored.
•Fats
– Fatty acids can be used for energy.
– Fatty acids are a highly concentrated energy source.
– Store excess calories.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Metabolism (cont.)
Nutrient Metabolism (cont.)
•Proteins
– No specialized storage forms for protein.
– Specific proteins are synthesized to meet specific
body needs.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Metabolism (cont.)
✓
Checkpoints
20-1 What are the two types of activities that make
up metabolism?
20-2 What name is given to the series of cellular
reactions that releases energy from nutrients?
20-3 What is the organic end product of glycolysis?
20-4 What element is required for aerobic cellular
respiration but not for glycolysis?
20-5 What is removed from amino acids before they are
metabolized for energy?
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines
Learning Objectives
6.List the recommended percentages of
carbohydrate, fat, and protein in the diet.
7. Distinguish between simple and
complex carbohydrates, giving examples
of each.
8.Compare saturated and unsaturated
fats.
9. Define essential amino acid.
10. Explain the roles of minerals and
vitamins in nutrition and give examples
of each.
11. List six adverse effects of alcohol
consumption.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Percentage of Calories in Daily Diet
•Carbohydrate: 55% to 60%
•Fat: 30% or less
•Protein: 15% to 20%
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Carbohydrates
•Types
– Simple sugars (monosaccharides)
– Complex carbohydrates (polysaccharides)
• Starches
• Fibers
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Fats
•Moderate amounts are necessary.
•Essential fatty acids:
–Linoleic acid
–Alpha-linolenic acid
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Fats (cont.)
•Saturated and unsaturated fats
– Saturated fats
• Most are from animal sources.
• Solid at room temperature.
– Unsaturated fats
• Derived from plants
• Liquid at room temperature
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Figure 20-2 Saturated and
unsaturated fats.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Proteins
•Essential amino acids
– Most animal proteins supply all of the essential
amino acids (complete).
•Nonessential amino acids
– Can be synthesized by the body
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Figure 20-3 Combining foods to obtain the essential
amino acids.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Minerals and Vitamins
•Minerals are chemical elements necessary for:
– Body structure
– Fluid balance
– Muscle contraction
– Nerve impulse conduction
– Blood clotting
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Minerals and Vitamins (cont.)
•Vitamins are complex organic substances.
– Water soluble
– Fat soluble
•Some are antioxidants.
– Stabilize free radicals
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Minerals and Vitamins (cont.)
•Vitamin and mineral supplements
– Supplements are controversial.
– Some populations may benefit from them.
– Some vitamins cause toxic effects when taken in
excess.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
USDA Guidelines
•MyPlate updated guidelines in 2011
•ChooseMyPlate.gov
– Guidelines for individual variation
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Figure 20-4 USDA dietary guidelines.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
Alcohol
•Not a nutrient
•Interferes with metabolism
•Should be consumed only in moderation
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Guidelines (cont.)
✓
Checkpoints
20-6 What is the term for how rapidly a food raises the
blood glucose level?
20-7 What is meant when an amino acid or a fatty acid is
described as essential?
20-8 What is the difference between saturated and
unsaturated fats?
20-9 What is the difference between vitamins and
minerals?
20-10 How much pure alcohol can the average person
metabolize per hour?
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Disorders
Learning Objective
12. Describe four nutritional
disorders.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Disorders (cont.)
Food Allergies
•Allergens can be food or food additives.
•Allergic reactions usually involve the:
– Skin
– Respiratory tract
– Gastrointestinal tract
•Reactions can be fatal in extremely sensitive individuals.
Nonallergic Adverse Food Reactions
– Result of enzyme deficiency
– Gastrointestinal symptoms
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Disorders (cont.)
Malnutrition
•Can occur from missing nutrients or eating too much of
wrong foods
•Protein–energy malnutrition (PEM)
•Marasmus
•Kwashiorkor
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Figure 20-5 Effects of kwashiorkor.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Disorders (cont.)
Weight Control
•Body mass index (BMI)
•Overweight and obesity
– Measured by body mass index (BMI)
• Overweight is BMI of 25 to 30.
• Obese is BMI greater than 30.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Disorders (cont.)
Weight Control (cont.)
•Underweight
– BMI less than 18.5
– May result from:
• Eating disorders (anorexia, bulimia)
• Rapid growth
• Allergies
• Illness
• Psychological factors
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Figure 20-6 Calculation of body mass index (BMI).
What is the BMI of a man 5′10″ in height who weighs 170
pounds? (Round off to one decimal place.)
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutritional Disorders (cont.)
✓
Checkpoints
20-11 What condition results from lack of any specific
nutrient in the diet?
20-12 What does the abbreviation BMI stand for?
20-13 What term applies to any chronic loss of appetite?
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Nutrition and Aging
• Nutritional deficiencies may develop.
• Senses of smell and taste decline.
• Ability to synthesize vitamin D and calcium declines.
• Medications may interfere with appetite and absorption.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Body Temperature
Learning Objectives
13. Explain how heat is produced
and lost in the body.
14. Describe the role of the hypothalamus
in regulating body temperature.
15. Explain the role of fever in disease.
16. Describe responses to excessive heat
and cold.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Body Temperature (cont.)
• Heat is by-product of chemical activities in body tissues.
• Regulatory devices keep body temperature constant
within narrow limits.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Body Temperature (cont.)
Heat Production
Heat production directly correlates with tissue activity.
•Muscle cell activity and heat production increase with
exercise.
•Food intake augments heat production.
•Hormone production.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Body Temperature (cont.)
Heat Loss
•Mechanisms of heat loss :
– Radiation
– Convection
– Evaporation
– Conduction
•Prevention of heat loss
– Volume of tissue compared with amount of skin
surface is a factor.
– Natural insulation.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Figure 20-7 Mechanisms of heat loss.
What will happen in (B) if the fan speed is increased?
What will happen in (C) as environmental humidity
increases?
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Body Temperature (cont.)
Temperature Regulation
Integrating center for heat regulation is the hypothalamus.
•Responses to cold conditions
– Vasoconstriction
– Shivering
– Behavioral responses
•Responses to hot conditions
– Vasodilation
– Evaporation of sweat
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Figure 20-8 Thermoregulation.
Is blood flow in the skin higher under cold conditions or hot
conditions?
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Temperature Regulation (cont.)
•Age factors
– Newborns and elderly
• Reduced ability to produce heat
• Reduced ability to regulate overheating
• Should be protected from extreme temperatures
•Normal body temperature
– Normal range is 36.2°C to 37.6°C (97°F to 100°F).
– Varies with time of day.
– Varies by body part.
Body Temperature (cont.)
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Fever
•Higher than normal body temperature (febrile)
•Causes:
– Infection
– Malignancies
– Brain injuries
– Toxic reactions
– Vaccine reactions
– Central nervous system diseases
Body Temperature (cont.)
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Fever (cont.)
•Increase in metabolism proportional to the fever’s
intensity
•Crisis
– Profuse perspiration
– Muscular relaxation
– Vasodilation
•Lysis
•Antipyretic
Body Temperature (cont.)
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Responses to Excessive Heat
•Heat cramps
– Localized muscle cramping
•Heat exhaustion
– Heat retention and fluid loss
•Heat stroke
– A medical emergency that can be fatal
Body Temperature (cont.)
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Body Temperature (cont.)
Responses to Excessive Cold
•Hypothermia
– Excessively low body temperature
– Cellular metabolism slows
•Frostbite
– Can cause permanent local tissue damage.
– Likely areas are face, ears, extremities.
– Young and elderly and those with circulatory
disorders are susceptible to cold injuries.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Body Temperature (cont.)
✓
Checkpoints
20-14 What part of the brain is responsible for regulating
body temperature?
20-15 What does an antipyretic drug do?
20-16 What change occurs in cutaneous blood vessels
under cold conditions? Under hot conditions?
20-17 What is the term for excessively low body
temperature?
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Case Study
Learning Objective
17. Using the case study
and the text, define
anorexia nervosa, and list
some of its adverse effects.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Case Study (cont.)
Anorexia Nervosa
•Psychological disorder
•Desire to be excessively thin
– Starvation
•Body resorts to breaking down proteins to produce
energy
•Results of the unhealthy eating behavior:
– Loss of bone protein
– Loss of cardiac muscle
– Loss of skeletal muscle protein
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Word Anatomy
Learning Objective
18. Show how word parts are used to build words related
to metabolism, nutrition, and body temperature.
Copyright © 2015 Wolters Kluwer • All Rights Reserved
Word Anatomy (cont.)
Copyright © 2015 Wolters Kluwer • All Rights Reserved

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HBHD 13e Ch20

  • 1. Copyright © 2015 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 20 Metabolism, Nutrition, and Body Temperature
  • 2. Copyright © 2015 Wolters Kluwer • All Rights Reserved Overview
  • 3. Copyright © 2015 Wolters Kluwer • All Rights Reserved Key Terms anabolism glycogen metabolic rate basal metabolism glycolysis mineral catabolism hypothalamus oxidation cellular respiration hypothermia pyrogen fever kilocalorie vitamin glucose malnutrition
  • 4. Copyright © 2015 Wolters Kluwer • All Rights Reserved Metabolism Learning Objectives 1. Differentiate between catabolism and anabolism. 2. Differentiate between the anaerobic and aerobic phases of glucose catabolism and give the end products and the relative amount of energy released by each. 3.Define metabolic rate and name six factors that affect it. 4. Explain how carbohydrates, fats, and proteins are metabolized for energy. 5. Compare the energy contents of carbohydrates, fats, and proteins.
  • 5. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines Learning Objectives 6.List the recommended percentages of carbohydrate, fat, and protein in the diet. 7. Distinguish between simple and complex carbohydrates, giving examples of each. 8.Compare saturated and unsaturated fats. 9. Define essential amino acid. 10. Explain the roles of minerals and vitamins in nutrition and give examples of each. 11. List six adverse effects of alcohol consumption.
  • 6. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Disorders Learning Objective 12. Describe four nutritional disorders.
  • 7. Copyright © 2015 Wolters Kluwer • All Rights Reserved Body Temperature Learning Objectives 13. Explain how heat is produced and lost in the body. 14. Describe the role of the hypothalamus in regulating body temperature. 15. Explain the role of fever in disease. 16. Describe responses to excessive heat and cold.
  • 8. Copyright © 2015 Wolters Kluwer • All Rights Reserved Case Study Learning Objective 17. Using the case study and the text, define anorexia nervosa, and list some of its adverse effects.
  • 9. Copyright © 2015 Wolters Kluwer • All Rights Reserved Word Anatomy Learning Objective 18. Show how word parts are used to build words related to metabolism, nutrition, and body temperature.
  • 10. Copyright © 2015 Wolters Kluwer • All Rights Reserved Metabolism Types of Metabolic Activities •Catabolism – Breaks down complex compounds into simpler compounds •Anabolism – Builds simple compounds into needed substances
  • 11. Copyright © 2015 Wolters Kluwer • All Rights Reserved Metabolism (cont.) Cellular Respiration •Glucose catabolism: anaerobic phase (glycolysis) – Location: Cytoplasm – Yield: 2 ATP per glucose molecule – End product: Pyruvic acid •Glucose catabolism: Aerobic phase – Location: Mitochondria – Yield: 32 ATP per glucose molecule – End products: CO2 and H2O
  • 12. Copyright © 2015 Wolters Kluwer • All Rights Reserved Metabolism (cont.) Cellular Respiration (cont.) •Cellular respiration of fatty acids and amino acids – Oxidized to generate energy through aerobic mechanisms
  • 13. Copyright © 2015 Wolters Kluwer • All Rights Reserved Figure 20-1 Cellular respiration. What does pyruvic acid produce when it is metabolized anaerobically? What does it produce when metabolized completely using oxygen?
  • 14. Copyright © 2015 Wolters Kluwer • All Rights Reserved Metabolism (cont.) Metabolic Rate •Rate at which cellular respiration converts nutrients into ATP •Decreases with age •Basal metabolism •Measured in kilocalories (kcal)
  • 15. Copyright © 2015 Wolters Kluwer • All Rights Reserved Metabolism (cont.) Nutrient Metabolism •Carbohydrates – Glucose is the major energy source for cells. – Glycogen is storage form of carbohydrates. • Glycogen broken down to yield glucose. – Excess glucose converted to fat and stored. •Fats – Fatty acids can be used for energy. – Fatty acids are a highly concentrated energy source. – Store excess calories.
  • 16. Copyright © 2015 Wolters Kluwer • All Rights Reserved Metabolism (cont.) Nutrient Metabolism (cont.) •Proteins – No specialized storage forms for protein. – Specific proteins are synthesized to meet specific body needs.
  • 17. Copyright © 2015 Wolters Kluwer • All Rights Reserved Metabolism (cont.) ✓ Checkpoints 20-1 What are the two types of activities that make up metabolism? 20-2 What name is given to the series of cellular reactions that releases energy from nutrients? 20-3 What is the organic end product of glycolysis? 20-4 What element is required for aerobic cellular respiration but not for glycolysis? 20-5 What is removed from amino acids before they are metabolized for energy?
  • 18. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines Learning Objectives 6.List the recommended percentages of carbohydrate, fat, and protein in the diet. 7. Distinguish between simple and complex carbohydrates, giving examples of each. 8.Compare saturated and unsaturated fats. 9. Define essential amino acid. 10. Explain the roles of minerals and vitamins in nutrition and give examples of each. 11. List six adverse effects of alcohol consumption.
  • 19. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Percentage of Calories in Daily Diet •Carbohydrate: 55% to 60% •Fat: 30% or less •Protein: 15% to 20%
  • 20. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Carbohydrates •Types – Simple sugars (monosaccharides) – Complex carbohydrates (polysaccharides) • Starches • Fibers
  • 21. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Fats •Moderate amounts are necessary. •Essential fatty acids: –Linoleic acid –Alpha-linolenic acid
  • 22. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Fats (cont.) •Saturated and unsaturated fats – Saturated fats • Most are from animal sources. • Solid at room temperature. – Unsaturated fats • Derived from plants • Liquid at room temperature
  • 23. Copyright © 2015 Wolters Kluwer • All Rights Reserved Figure 20-2 Saturated and unsaturated fats.
  • 24. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Proteins •Essential amino acids – Most animal proteins supply all of the essential amino acids (complete). •Nonessential amino acids – Can be synthesized by the body
  • 25. Copyright © 2015 Wolters Kluwer • All Rights Reserved Figure 20-3 Combining foods to obtain the essential amino acids.
  • 26. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Minerals and Vitamins •Minerals are chemical elements necessary for: – Body structure – Fluid balance – Muscle contraction – Nerve impulse conduction – Blood clotting
  • 27. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Minerals and Vitamins (cont.) •Vitamins are complex organic substances. – Water soluble – Fat soluble •Some are antioxidants. – Stabilize free radicals
  • 28. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Minerals and Vitamins (cont.) •Vitamin and mineral supplements – Supplements are controversial. – Some populations may benefit from them. – Some vitamins cause toxic effects when taken in excess.
  • 29. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) USDA Guidelines •MyPlate updated guidelines in 2011 •ChooseMyPlate.gov – Guidelines for individual variation
  • 30. Copyright © 2015 Wolters Kluwer • All Rights Reserved Figure 20-4 USDA dietary guidelines.
  • 31. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) Alcohol •Not a nutrient •Interferes with metabolism •Should be consumed only in moderation
  • 32. Copyright © 2015 Wolters Kluwer • All Rights Reserved
  • 33. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Guidelines (cont.) ✓ Checkpoints 20-6 What is the term for how rapidly a food raises the blood glucose level? 20-7 What is meant when an amino acid or a fatty acid is described as essential? 20-8 What is the difference between saturated and unsaturated fats? 20-9 What is the difference between vitamins and minerals? 20-10 How much pure alcohol can the average person metabolize per hour?
  • 34. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Disorders Learning Objective 12. Describe four nutritional disorders.
  • 35. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Disorders (cont.) Food Allergies •Allergens can be food or food additives. •Allergic reactions usually involve the: – Skin – Respiratory tract – Gastrointestinal tract •Reactions can be fatal in extremely sensitive individuals. Nonallergic Adverse Food Reactions – Result of enzyme deficiency – Gastrointestinal symptoms
  • 36. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Disorders (cont.) Malnutrition •Can occur from missing nutrients or eating too much of wrong foods •Protein–energy malnutrition (PEM) •Marasmus •Kwashiorkor
  • 37. Copyright © 2015 Wolters Kluwer • All Rights Reserved Figure 20-5 Effects of kwashiorkor.
  • 38. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Disorders (cont.) Weight Control •Body mass index (BMI) •Overweight and obesity – Measured by body mass index (BMI) • Overweight is BMI of 25 to 30. • Obese is BMI greater than 30.
  • 39. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Disorders (cont.) Weight Control (cont.) •Underweight – BMI less than 18.5 – May result from: • Eating disorders (anorexia, bulimia) • Rapid growth • Allergies • Illness • Psychological factors
  • 40. Copyright © 2015 Wolters Kluwer • All Rights Reserved
  • 41. Copyright © 2015 Wolters Kluwer • All Rights Reserved Figure 20-6 Calculation of body mass index (BMI). What is the BMI of a man 5′10″ in height who weighs 170 pounds? (Round off to one decimal place.)
  • 42. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutritional Disorders (cont.) ✓ Checkpoints 20-11 What condition results from lack of any specific nutrient in the diet? 20-12 What does the abbreviation BMI stand for? 20-13 What term applies to any chronic loss of appetite?
  • 43. Copyright © 2015 Wolters Kluwer • All Rights Reserved Nutrition and Aging • Nutritional deficiencies may develop. • Senses of smell and taste decline. • Ability to synthesize vitamin D and calcium declines. • Medications may interfere with appetite and absorption.
  • 44. Copyright © 2015 Wolters Kluwer • All Rights Reserved Body Temperature Learning Objectives 13. Explain how heat is produced and lost in the body. 14. Describe the role of the hypothalamus in regulating body temperature. 15. Explain the role of fever in disease. 16. Describe responses to excessive heat and cold.
  • 45. Copyright © 2015 Wolters Kluwer • All Rights Reserved Body Temperature (cont.) • Heat is by-product of chemical activities in body tissues. • Regulatory devices keep body temperature constant within narrow limits.
  • 46. Copyright © 2015 Wolters Kluwer • All Rights Reserved Body Temperature (cont.) Heat Production Heat production directly correlates with tissue activity. •Muscle cell activity and heat production increase with exercise. •Food intake augments heat production. •Hormone production.
  • 47. Copyright © 2015 Wolters Kluwer • All Rights Reserved Body Temperature (cont.) Heat Loss •Mechanisms of heat loss : – Radiation – Convection – Evaporation – Conduction •Prevention of heat loss – Volume of tissue compared with amount of skin surface is a factor. – Natural insulation.
  • 48. Copyright © 2015 Wolters Kluwer • All Rights Reserved Figure 20-7 Mechanisms of heat loss. What will happen in (B) if the fan speed is increased? What will happen in (C) as environmental humidity increases?
  • 49. Copyright © 2015 Wolters Kluwer • All Rights Reserved Body Temperature (cont.) Temperature Regulation Integrating center for heat regulation is the hypothalamus. •Responses to cold conditions – Vasoconstriction – Shivering – Behavioral responses •Responses to hot conditions – Vasodilation – Evaporation of sweat
  • 50. Copyright © 2015 Wolters Kluwer • All Rights Reserved Figure 20-8 Thermoregulation. Is blood flow in the skin higher under cold conditions or hot conditions?
  • 51. Copyright © 2015 Wolters Kluwer • All Rights Reserved Temperature Regulation (cont.) •Age factors – Newborns and elderly • Reduced ability to produce heat • Reduced ability to regulate overheating • Should be protected from extreme temperatures •Normal body temperature – Normal range is 36.2°C to 37.6°C (97°F to 100°F). – Varies with time of day. – Varies by body part. Body Temperature (cont.)
  • 52. Copyright © 2015 Wolters Kluwer • All Rights Reserved Fever •Higher than normal body temperature (febrile) •Causes: – Infection – Malignancies – Brain injuries – Toxic reactions – Vaccine reactions – Central nervous system diseases Body Temperature (cont.)
  • 53. Copyright © 2015 Wolters Kluwer • All Rights Reserved Fever (cont.) •Increase in metabolism proportional to the fever’s intensity •Crisis – Profuse perspiration – Muscular relaxation – Vasodilation •Lysis •Antipyretic Body Temperature (cont.)
  • 54. Copyright © 2015 Wolters Kluwer • All Rights Reserved Responses to Excessive Heat •Heat cramps – Localized muscle cramping •Heat exhaustion – Heat retention and fluid loss •Heat stroke – A medical emergency that can be fatal Body Temperature (cont.)
  • 55. Copyright © 2015 Wolters Kluwer • All Rights Reserved Body Temperature (cont.) Responses to Excessive Cold •Hypothermia – Excessively low body temperature – Cellular metabolism slows •Frostbite – Can cause permanent local tissue damage. – Likely areas are face, ears, extremities. – Young and elderly and those with circulatory disorders are susceptible to cold injuries.
  • 56. Copyright © 2015 Wolters Kluwer • All Rights Reserved Body Temperature (cont.) ✓ Checkpoints 20-14 What part of the brain is responsible for regulating body temperature? 20-15 What does an antipyretic drug do? 20-16 What change occurs in cutaneous blood vessels under cold conditions? Under hot conditions? 20-17 What is the term for excessively low body temperature?
  • 57. Copyright © 2015 Wolters Kluwer • All Rights Reserved Case Study Learning Objective 17. Using the case study and the text, define anorexia nervosa, and list some of its adverse effects.
  • 58. Copyright © 2015 Wolters Kluwer • All Rights Reserved Case Study (cont.) Anorexia Nervosa •Psychological disorder •Desire to be excessively thin – Starvation •Body resorts to breaking down proteins to produce energy •Results of the unhealthy eating behavior: – Loss of bone protein – Loss of cardiac muscle – Loss of skeletal muscle protein
  • 59. Copyright © 2015 Wolters Kluwer • All Rights Reserved Word Anatomy Learning Objective 18. Show how word parts are used to build words related to metabolism, nutrition, and body temperature.
  • 60. Copyright © 2015 Wolters Kluwer • All Rights Reserved Word Anatomy (cont.)
  • 61. Copyright © 2015 Wolters Kluwer • All Rights Reserved