HANDI Summit 18 - Introducing HANDI-HOPD - Dr Ian McNicollHANDI HEALTH
NHS England hosted the HANDI-HOPD Summit in London on the 18th September. This was attended by an invited audience of around 40 people to discuss plans to take the HANDI-HOPD platform forward to the NHS England Open Source Open Day on the 26th of November in Newcastle-Upon-Tyne where is will be launched as the Platform for NHS Code4Health.
Dr Ian McNicoll, gave an overview of how the platform worked and a description of the key open standards and how the could be used by developers to rapidly build interoperable health and care software. He also described how the platform provided a rigorous process fro the development, curation and publication of clinical content models and facilitated the easy engagement of clinicians in the process.
Google Cloud healthcare data platform and FHIR APIs by Kalyan PamarthyHealthDev
Kalyan Pamarthy, product management for the FHIR® and HL7 v2 data platform within Google Cloud AI.
"Google Cloud healthcare data platform and FHIR® APIs"
This presentation will provide a high-level view of the Google Cloud healthcare data platform, managed FHIR® APIs, and capabilities that support end-end customer use cases for healthcare data interoperability. It will also cover key themes around the adoption of FHIR and implementation patterns followed by Google Cloud's customers transitioning to FHIR®.
CMS Interoperability and Patient Access final rule and Health Samurai FHIR pl...HealthDev
Pavel Smirnov, CEO of Health Samurai.
CMS Interoperability and Patient Access final rule for health plans
CMS has released Patient Access final rule for health plans. By July 1, 2021, health plans must allow their members to access their claims and encounter information over standards-based secure API (FHIR® 4.0.1). Pavel analyzed the rule in detail and share the checklist that any health plan can use. Then he explained the technology that Health Samurai has built to allow health plans comply with the rule.
Pavel Smirnov, Health Samurai - FHIR business opportunitiesHealthDev
Pavel analyzes and explains business opportunities created by the FHIR standard such as Patient Access to Data, Extending existing health records solutions, Development of new FHIR-first solutions, Data Analytics, and FHIR tooling.
He also makes an introduction to the FHIR meetups in the Bay Area.
HANDI Summit 18 - Introducing HANDI-HOPD - Dr Ian McNicollHANDI HEALTH
NHS England hosted the HANDI-HOPD Summit in London on the 18th September. This was attended by an invited audience of around 40 people to discuss plans to take the HANDI-HOPD platform forward to the NHS England Open Source Open Day on the 26th of November in Newcastle-Upon-Tyne where is will be launched as the Platform for NHS Code4Health.
Dr Ian McNicoll, gave an overview of how the platform worked and a description of the key open standards and how the could be used by developers to rapidly build interoperable health and care software. He also described how the platform provided a rigorous process fro the development, curation and publication of clinical content models and facilitated the easy engagement of clinicians in the process.
Google Cloud healthcare data platform and FHIR APIs by Kalyan PamarthyHealthDev
Kalyan Pamarthy, product management for the FHIR® and HL7 v2 data platform within Google Cloud AI.
"Google Cloud healthcare data platform and FHIR® APIs"
This presentation will provide a high-level view of the Google Cloud healthcare data platform, managed FHIR® APIs, and capabilities that support end-end customer use cases for healthcare data interoperability. It will also cover key themes around the adoption of FHIR and implementation patterns followed by Google Cloud's customers transitioning to FHIR®.
CMS Interoperability and Patient Access final rule and Health Samurai FHIR pl...HealthDev
Pavel Smirnov, CEO of Health Samurai.
CMS Interoperability and Patient Access final rule for health plans
CMS has released Patient Access final rule for health plans. By July 1, 2021, health plans must allow their members to access their claims and encounter information over standards-based secure API (FHIR® 4.0.1). Pavel analyzed the rule in detail and share the checklist that any health plan can use. Then he explained the technology that Health Samurai has built to allow health plans comply with the rule.
Pavel Smirnov, Health Samurai - FHIR business opportunitiesHealthDev
Pavel analyzes and explains business opportunities created by the FHIR standard such as Patient Access to Data, Extending existing health records solutions, Development of new FHIR-first solutions, Data Analytics, and FHIR tooling.
He also makes an introduction to the FHIR meetups in the Bay Area.
Nick Radov, Payer/Provider - Interoperability & HL7 Da Vinci Project.HealthDev
The HL7 Da Vinci Project is an industry initiative to develop payer/provider interoperability use cases based on FHIR for value-based care. Da Vinci members write free implementation guides and create open-source reference implementations which any healthcare organization can use. This presentation will cover the project history, give a summary of current use cases, explain the development process, and dive into the technical aspects of a few key use cases. We will also cover how UnitedHealthcare has leveraged Da Vinci Project in our EMR Integration Service Layer (EISL) which acts as a gateway between that payer’s internal systems and their network providers.
Pavel Smirnov. FHIR-first application development.HealthDev
Besides enabling interoperability FHIR can power the innovation and development of new healthcare solutions via providing a solid data model, modern API, a lot of open-source and commercial tooling, and an active community. Pavel will introduce FHIR-first application development, explain its benefits, and difference.
IHE product selection and acceptance testingCor Loef
IHE, Integrating the Healthcare Enterprise, creates solutions for interoperability problems in healthcare by developing standards based interface specifications. Healthcare ICT products that have implemented the IHE specifications make the integration efforts for an eHealth solution much easier. Conformity assessment in the deployment process towards an operational application portfolio is supported by a proven test methodology and Open Source test tools.
Patient portals and personal health apps in New ZealandAlastair Kenworthy
Trusted personal health apps will have access to patient portals for the secure exchange of information recorded about the person and their health care.
AAPAT utilizes advanced RFID technology to track in real time the location of patients and associated mobile hospital assets (clinical staff, beds, pumps, monitors, etc.).
Anish Arora - Playing With FHIR - A Practical ApproachHealthDev
Is FHIR truly the holy grail of interoperability in Healthcare? Learn about common pitfalls in real-world enterprise-scale FHIR implementations and how to approach them pragmatically — also a look at some exciting new developments in the works.
The newly developed electronic health system can play a vital role in the remote regions of emerging and developing countries although sometimes it seems difficult due to the lack of communication infrastructure. E-Health can be a promising aspect for providing public health benefits if it integrates with the conventional medical system. More strategic approaches are necessary for the planning, development, and evaluation of e-Health. This article is written to depict the existing and future opportunities of e-Health in the health support system.
[WSO2 Summit Americas 2020] Towards Greater Interoperability With A Proven In...WSO2
Healthcare records are increasingly becoming digitized. As patients move around the healthcare ecosystem, their electronic health records must be available, discoverable, and understandable. Further, to support automated clinical decisions and other machine-based processing, the data must also be structured and standardized. This is becoming a matter of interest for institutes such as government agencies and regional bodies, and we are already seeing rules and regulations come into action.
Fast Healthcare Interoperability Resources (FHIR®) is a next-generation standard framework created by HL7 combining the best features of previous HL7 standards. FHIR® leverages the latest web standards and focuses on ease of implementability.
In this deck, Nirmal will introduce WSO2 Healthcare Integration Platform and demonstrate how it boosts developer productivity when exposing FHIR® APIs.
Code4Health, pop up uni, 2pm, 2 september 2015NHS England
Expo is the most significant annual health and social care event in the calendar, uniting more NHS and care leaders, commissioners, clinicians, voluntary sector partners, innovators and media than any other health and care event.
Expo 15 returned to Manchester and was hosted once again by NHS England. Around 5000 people a day from health and care, the voluntary sector, local government, and industry joined together at Manchester Central Convention Centre for two packed days of speakers, workshops, exhibitions and professional development.
This year, Expo was more relevant and engaging than ever before, happening within the first 100 days of the new Government, and almost 12 months after the publication of the NHS Five Year Forward View. It was also a great opportunity to check on and learn from the progress of Greater Manchester as the area prepares to take over a £6 billion devolved health and social care budget, pledging to integrate hospital, community, primary and social care and vastly improve health and well-being.
More information is available online: www.expo.nhs.uk
The document outlines KMGs capabilities in the Health IT sector. Key Management Group (KMG) provides software services to Hospitals, Billing Companies, EMR Companies, Transcription Companies & Physicians. View more details at www.kmgus.com
Combining Healthcare Standards with Other RESTful APIsBrad Genereaux
Understand the value in connecting non-healthcare REST APIs
Understand the general methods to accomplish this
Understand the risks and mitigation strategies in doing this
Aziz Boxwala, MD, Ph.D. SMART-on-FHIR specification & Sapphire demo.HealthDev
Aziz Boxwala will provide an overview of the SMART-on-FHIR specification for creating apps that integrate with electronic health record systems, describe how these apps can be used to meet different workflow needs and provide clinical decision support. He will demonstrate Sapphire, a tool for assembling SMART-on-FHIR apps rapidly using a drag-and-drop interface.
HANDI Summit 18 - Introducing HANDI-HOPD - Ewan DavisHANDI HEALTH
NHS England hosted the HANDI-HOPD Summit in London on the 18th September. This was attended by an invited audience of around 40 people to discuss plans to take the HANDI-HOPD platform forward to the NHS England Open Source Open Day on the 26th of November in Newcastle-Upon-Tyne where is will be launched as the Platform for NHS Code4Health.
HANDI-HOPD The HANDI Open Platform Demonstrator provides an experimental platform to demonstrate the power of emerging open standards and APIs to deliver the transformational power of the Internet to support digital health and care.
Ewan Davis introduced the HOPD, described where it fitted in the global development of open health platforms what had already been deployed and our plans for it’s development.
Nick Radov, Payer/Provider - Interoperability & HL7 Da Vinci Project.HealthDev
The HL7 Da Vinci Project is an industry initiative to develop payer/provider interoperability use cases based on FHIR for value-based care. Da Vinci members write free implementation guides and create open-source reference implementations which any healthcare organization can use. This presentation will cover the project history, give a summary of current use cases, explain the development process, and dive into the technical aspects of a few key use cases. We will also cover how UnitedHealthcare has leveraged Da Vinci Project in our EMR Integration Service Layer (EISL) which acts as a gateway between that payer’s internal systems and their network providers.
Pavel Smirnov. FHIR-first application development.HealthDev
Besides enabling interoperability FHIR can power the innovation and development of new healthcare solutions via providing a solid data model, modern API, a lot of open-source and commercial tooling, and an active community. Pavel will introduce FHIR-first application development, explain its benefits, and difference.
IHE product selection and acceptance testingCor Loef
IHE, Integrating the Healthcare Enterprise, creates solutions for interoperability problems in healthcare by developing standards based interface specifications. Healthcare ICT products that have implemented the IHE specifications make the integration efforts for an eHealth solution much easier. Conformity assessment in the deployment process towards an operational application portfolio is supported by a proven test methodology and Open Source test tools.
Patient portals and personal health apps in New ZealandAlastair Kenworthy
Trusted personal health apps will have access to patient portals for the secure exchange of information recorded about the person and their health care.
AAPAT utilizes advanced RFID technology to track in real time the location of patients and associated mobile hospital assets (clinical staff, beds, pumps, monitors, etc.).
Anish Arora - Playing With FHIR - A Practical ApproachHealthDev
Is FHIR truly the holy grail of interoperability in Healthcare? Learn about common pitfalls in real-world enterprise-scale FHIR implementations and how to approach them pragmatically — also a look at some exciting new developments in the works.
The newly developed electronic health system can play a vital role in the remote regions of emerging and developing countries although sometimes it seems difficult due to the lack of communication infrastructure. E-Health can be a promising aspect for providing public health benefits if it integrates with the conventional medical system. More strategic approaches are necessary for the planning, development, and evaluation of e-Health. This article is written to depict the existing and future opportunities of e-Health in the health support system.
[WSO2 Summit Americas 2020] Towards Greater Interoperability With A Proven In...WSO2
Healthcare records are increasingly becoming digitized. As patients move around the healthcare ecosystem, their electronic health records must be available, discoverable, and understandable. Further, to support automated clinical decisions and other machine-based processing, the data must also be structured and standardized. This is becoming a matter of interest for institutes such as government agencies and regional bodies, and we are already seeing rules and regulations come into action.
Fast Healthcare Interoperability Resources (FHIR®) is a next-generation standard framework created by HL7 combining the best features of previous HL7 standards. FHIR® leverages the latest web standards and focuses on ease of implementability.
In this deck, Nirmal will introduce WSO2 Healthcare Integration Platform and demonstrate how it boosts developer productivity when exposing FHIR® APIs.
Code4Health, pop up uni, 2pm, 2 september 2015NHS England
Expo is the most significant annual health and social care event in the calendar, uniting more NHS and care leaders, commissioners, clinicians, voluntary sector partners, innovators and media than any other health and care event.
Expo 15 returned to Manchester and was hosted once again by NHS England. Around 5000 people a day from health and care, the voluntary sector, local government, and industry joined together at Manchester Central Convention Centre for two packed days of speakers, workshops, exhibitions and professional development.
This year, Expo was more relevant and engaging than ever before, happening within the first 100 days of the new Government, and almost 12 months after the publication of the NHS Five Year Forward View. It was also a great opportunity to check on and learn from the progress of Greater Manchester as the area prepares to take over a £6 billion devolved health and social care budget, pledging to integrate hospital, community, primary and social care and vastly improve health and well-being.
More information is available online: www.expo.nhs.uk
The document outlines KMGs capabilities in the Health IT sector. Key Management Group (KMG) provides software services to Hospitals, Billing Companies, EMR Companies, Transcription Companies & Physicians. View more details at www.kmgus.com
Combining Healthcare Standards with Other RESTful APIsBrad Genereaux
Understand the value in connecting non-healthcare REST APIs
Understand the general methods to accomplish this
Understand the risks and mitigation strategies in doing this
Aziz Boxwala, MD, Ph.D. SMART-on-FHIR specification & Sapphire demo.HealthDev
Aziz Boxwala will provide an overview of the SMART-on-FHIR specification for creating apps that integrate with electronic health record systems, describe how these apps can be used to meet different workflow needs and provide clinical decision support. He will demonstrate Sapphire, a tool for assembling SMART-on-FHIR apps rapidly using a drag-and-drop interface.
HANDI Summit 18 - Introducing HANDI-HOPD - Ewan DavisHANDI HEALTH
NHS England hosted the HANDI-HOPD Summit in London on the 18th September. This was attended by an invited audience of around 40 people to discuss plans to take the HANDI-HOPD platform forward to the NHS England Open Source Open Day on the 26th of November in Newcastle-Upon-Tyne where is will be launched as the Platform for NHS Code4Health.
HANDI-HOPD The HANDI Open Platform Demonstrator provides an experimental platform to demonstrate the power of emerging open standards and APIs to deliver the transformational power of the Internet to support digital health and care.
Ewan Davis introduced the HOPD, described where it fitted in the global development of open health platforms what had already been deployed and our plans for it’s development.
Today's Electronic Health Record (EHR) offerings inhibit the ability to develop the next generation of clinical applications for providers to provide the best possible care and patients to become more engaged. Such offerings are designed as monolithic silos of storage and end-user experience that use proprietary methods for accessing key functionality. While large health care providers typically have physical control over their data, they lack in having functional control. This barrier makes it virtually impossible for data to be easily accessed by other applications without very costly and time-consuming migration strategies. As a result, the pace of innovation is greatly stymied by closed systems that appear to be all-too-prevalent in the healthcare industry. This session presents a strategy of vendor-neutral, public, open Application Programming Interfaces (APIs) and advocates for their use in developing open platforms for healthcare applications.
Data Harmonization for a Molecularly Driven Health SystemWarren Kibbe
Seminar for Dr. Min Zhang's Purdue Bioinformatics Seminar Series. Touched on learning health systems, the Gen3 Data Commons, the NCI Genomic Data Commons, Data Harmonization, FAIR, and open science.
Introduction to the 2012 Indivo X Users' Conference, including a history of Indivo and Personal Health Records, a discussion of the reasons for Google Health's demise, and how Indivo's open architecture might provide a solution.
By Kenneth Mandl, MD MPH, Faculty, Boston Children's Hospital Informatics Program.
NHS England share Code4Health ChallengeHANDI HEALTH
The NHS England Open Source Programme is creating a diverse range of solutions to increase choice, improve clinical practice and enhance patient engagement, including EHR, ePrescribing, departmental systems such as electronic observations, ophthalmology and integrated cross community portal solutions.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
1. Supporting the health ‘apps’ revolution
Software apps to support health and care - Supporting the app paradigm –
Creating a community of interest - That's HANDI
www.handihealth.org
Dr Ian McNicoll
HANDIHealth
openEHR Foundation
freshEHR Clinical Informatics
2. INTRODUCTION
2
Ian McNicoll
Former Glasgow GP
Health informatics
Director openEHR Foundation
freshEHR Clinical Informatics
Ocean Informatics UK
HANDIHealth
Commercial software developer
‘GP Accounts’
3. HANDI Health CIC
• A not-for-profit Community Enterprise
Company
• There to support:
– Developers
– Health and care professionals
– Patients, service users and carers
4. Apps: Lightweight Digital Tools
Not just about mobile
Narrow scope,a “connected thing”
Makes heavy use of pre-existing components
and services
Built using a well defined development and
deployment framework
Order of magnitude(s) faster and cheaper to
develop and deploy
Allows niche solutions and “fail fast”
5. What does HANDI do?
• Lobby for an environment (technical, cultural
and commercial) in which apps can flourish
interoperate and be orchestrated
6. HANDI is agnostic
• About
– Platforms
– Business models
– Standards
– Tools, services and approaches
• Show the community the possibilities and let
individuals decide
7. ‘open’
• Open data
– Analytics, quality monitoring
• Open APIs / standards
• ITK, GP2GP
• SMARTPlatform, FHIR
• Open source
– openEyes, Wardware
– Leeds Care Record
– Spine2
– “Safer Wards” Fund
7
8. Time for ‘open Platforms’?
• USA
• SMARTPlatforms
• Healthcare Services Collaboration Platform
• Intermountain, Cerner, Harris Healthcare
• GP Systems of Choice (GPSOC) refresh
• Phase 1 GP systems open APIs
• Phase 2 GP systems Common APIs
• De-facto ‘open platform’
8
13. The ‘HANDI Vision’
13
Apps
EPR
EHR PHR
PHR EMR
Meds
Repository
Drug KB
Terminology
Server
Service
Directory
CDS Service Pathways KB
Services/Repositories
Infrastructural Services
PDS/Record Discovery EWS ESB/Spine
Security
Broker
14. ‘Closed’ eHealth Platform
Proprietary Clinical Content / API
Proprietary value-
add components
Proprietary Querying and Persistence
Terminology
Server
Pathways KBESB/SpineITK Integration component
15. An open standards platform?
Closed OSS ClosedOSS
Vendor DVendor B Vendor CVendor A
API and messaging content based on open
source clinical content definitions
OSS
components
Vendor
solutions
Terminology
Server Pathways KB
ESB/SpineITK Integration component
Commit
Retrieve
16. ‘openEHR’ open Standards platform
Closed
source
Open
source
Open
source
openEHR
CDR
Vendor DVendor B Vendor CVendor A
Open source Archetype-based clinical
content information / querying model
OSS Value-add
components
Vendor
solutions
Terminology
Services Pathways KBESB/SpineITK Integration component
Commit
Retrieve
Query
17. Interoperability is not a tech problem
• Interoperability is a clinical problem
– Diverse recording practice (sometimes arbitrary)
– Diverse recording requirements
– Complexity / contextual nature of health data
– Lack of clinical involvement in standards development
• Too technical, too philosophical
• Too time-consuming, too slow
17
18. Current clinical content
standards methodology
• Antithesis of ‘agile’ development
– Inaccessible to clinicians
– Slow to develop, difficult to implement
– CDA implementation mostly ‘dumb documents’
– SNOMED has key role but ? oversold as whole solution
• Uncontrolled
– Multiple definitions of technical messaging models
• Approx 20 definitions of ‘allergy’ across UK
– No clear change request / problem report mechanism
18
19. Formal standards development
• “Arguably standards just get in the
way”
– Ewan Davis, HANDI
• Technical (ISB / ISO)
– Still largely a paper and
committee- bound process
• No clear problem
report/change request
mechanism
• Slow review cycles
• Professional (RCP ?PRSB)
– Aspirational guidelines
– Divorced from implementation
19
20. openEHR
Repository
(vendor #1)
openEHR
Repository [10]
(open source)
openEyes
(Moorfields)
“Safer Wards” Orsini
openEHR
Repository
(vendor #2)
openEHR API openEHR API
Local
SQL DB
openEHR API
Wardware2
(Kings)
NHS API
ESB / ITK / Spine components [2]
NHS Reporting
API
NHS
Care API
LCR apps
(Leeds)
openENT
(UCLP)
Clinical content
openEHR API integration [7]
EHRPaaS [9]
NHS API-
openEHR
Adaptors [8]
Professional
Records
Standards
Board
Professional oversight
21. open, shared data models: Archetypes
• Clinically-led + collaboratively authored
– open-source ‘crowd-sourcing’ methodology
– Shared open repository ‘CC-BY-SA’ licence
• Agility in response to continually changing clinical
demand
– Clear ownership, change request mechanism
– Tight version control
21
22.
23. Leeds NHS Care Record: open
Platform
openEHR Foundation accredited
Open Standards CDR Service layer
N3
hosted
ESB/Spine ITK Integration component
Commit
Retrieve
Query
OpenEHR Clinical Content “Archetypes”:
• Medication, allergies (GP2GP/ RCP/NHSS)
• Problems, procedures (international)
• End of Life content (ISB)
• Vital Signs, NEWS (international)
SMARTPlatforms
Open
APIs:
Leeds Clinical Portal via
SMARTPlatform APIs
‘OceanEHR’ Clinical
data repository
25. 25
SMARTPlatforms
Pluggable Webapp
API
HL7
Clinical Content
Exchange NHS API
inVivo
Datastore API
Detailed
Clinical Content
Development
Clinical leadership PRSB
Terminology
Centre
HSCIC
Non
openEHR
systems
Archetype+ SNOMED Clinical
Content definitions
A new mobile app
developer requires
plug in for care
record to test pulse
app functionality.
ITK+N3
29. NICE guidance on medicines reconciliation
Medication data models (RCP / GP2GP based)
Dummy Patient Health Record with realistic data
Data accessible via RESTful API
30. What did we set out to do?
• Create a patient-facing web-page for medication
reconciliation
• Populate existing medication list from GP system or
other source
• Enable patient to mark each item as
– Taking as prescribed / Changed dose
– No longer taking / Add new medication
• Save reconciled record back to server for onwards
transmission to GP
30
38. next tech steps for HANDI-HOPD
SMART and HL7 FHIR support
More openEHR providers
Cross provider querying demos
Cross provider transfers
Focus for openEHR ‘in-vivo’ API alignment
discussions
38
39. next steps for HANDI-HOPD?
• Direct discussion with NHS England
• possible use by Code4Health
• possible direct support for the ‘open
standards platform’ approach
• HOPD-HACKD hackday event in
September
39
40. Links
• twitter: @ianmcnicoll
• HANDI-HOPD handi-hopd.org/demo
• Ehrscape: dev.ehrscape.com
• Leeds Innovation Lab Health Platform : http://leedslabplatform.com
• openEHR Foundation : www.openehr.org
• International archetype repository: www.openehr.org/ckm
• UK archetype repository: www.clinicalmodels.org.uk